Etherification Synthetic Principle of Hydroxypropyl Methyl Cellulose (HPMC)

Hydroxypropyl methylcellulose (HPMC), yaiwisi mapadi, akhoza woyengedwa thonje kapena matabwa zamkati, m'pofunika kwambiri kuphwanya pamaso alkalization kapena pa alkalization, ndi kuphwanya ndi kudzera mawotchi mphamvu Kuwononga akaphatikiza dongosolo la mapadi zopangira kuchepetsa mlingo wa crystallinity ndi polymerization, kuonjezera padziko m'dera potero kuwongolera kupezeka ndi mankhwala anachita mphamvu zimene reagent kwa magulu atatu hydroxyl pa shuga mphete gulu la mapadi macromolecule.

Hydroxypropyl methylcellulose (HPMC) imagwiritsidwa ntchito ngati gawo lapansi lopangira mafuta, lomwe limatha kuzindikira kugwiritsa ntchito shuga okwana, kuwongolera kuchuluka kwa magwiritsidwe azinthu zopangira, kuchepetsa gawo lotsalira la gawo lapansi mumtsuko, ndikuchepetsa mtengo wamadzi onyansa. chithandizo. Izi hydroxypropyl methylcellulose Makhalidwe a methylcellulose ndi othandiza kukhathamiritsa kwa mtanda, kudyetsedwa-mtanda ndi mosalekeza nayonso mphamvu njira, kupewa mndandanda wa mavuto monga kulamulira zikuchokera sing'anga ndi dilution mlingo; zimathandizanso kuwongolera njira yowotchera. Popeza ntchito ya hydroxypropyl methylcellulose (HPMC) ndi yofanana ndi ma ether ena osungunuka m'madzi, imatha kugwiritsidwa ntchito mu utoto wa latex ndi zigawo za penti zosungunuka m'madzi monga filimu yopanga filimu, thickener, emulsifier ndi stabilizer, etc. kukana bwino kuvala, kusanja ndi kumamatira, ndipo kwasintha kugwedezeka kwapamwamba, kukhazikika kwa asidi ndi zamchere, komanso kugwirizana ndi inki yachitsulo.

Hydroxypropyl methylcellulose (HPMC) imakhala ndi zotsatira zabwino ngati zokhuthala za utoto woyera wa polyvinyl acetate. Mlingo wa m'malo mwa cellulose ether ukuwonjezeka, ndipo kukana kukokoloka kwa bakiteriya kumakulitsidwanso.

Ngakhale mfundo ya kaphatikizidwe ka etherification ya hydroxypropyl methyl cellulose (HPMC) sizovuta, imayenera kukhala alkali, zopangira pulverized, ndi alkaliized. Chilengedwe chilichonse cha etherification, zosungunulira zosungunulira, centrifugation, kutsuka ndi kuyanika kumaphatikizapo matekinoloje ambiri ofunikira komanso chidziwitso chochuluka.

Kwa mitundu yosiyanasiyana yazinthu, chilengedwe chilichonse chimakhala ndi zowongolera zaposachedwa, monga kutentha, nthawi, kupanikizika komanso kuwongolera kwazinthu. Zida zothandizira ndi zida zowongolera ndizotsimikizira zabwino zamtundu wokhazikika wazinthu komanso machitidwe odalirika opanga.