Kusiyana Pakati pa CMC ndi HPMC

Carboxymethyl cellulose (CMC) ndi hydroxypropyl methylcellulose (HPMC) ndi mitundu iwiri ya zotumphukira zama cellulose zomwe zimagwiritsidwa ntchito kwambiri m'mafakitale azakudya, azamankhwala, komanso chisamaliro chamunthu. Ngakhale onsewa amagwiritsidwa ntchito ngati zonenepa, zolimbitsa thupi, ndi zopangira ma emulsifiers, pali kusiyana kofunikira pakati pa CMC ndi HPMC komwe kumawapangitsa kukhala oyenera kugwiritsa ntchito zosiyanasiyana. M'nkhaniyi, tikambirana kusiyana pakati pa CMC ndi HPMC malinga ndi kapangidwe kake ka mankhwala, katundu, ntchito, ndi chitetezo.

1. Kapangidwe ka Chemical

CMC ndi polima yosungunuka m'madzi yomwe imachokera ku cellulose, yomwe ndi polima yachilengedwe yomwe imapezeka m'makoma a cellulose. Mapangidwe a mankhwala a CMC amadziwika ndi magulu a carboxymethyl (-CH2-COOH) omwe amamangiriridwa ku msana wa cellulose. Digiri ya substitution (DS) ya CMC imatanthawuza kuchuluka kwa magulu a carboxymethyl omwe amapezeka pa anhydroglucose unit (AGU) ya cellulose backbone. DS ya CMC imatha kuchoka pa 0.2 mpaka 1.5, ndi ma DS apamwamba omwe akuwonetsa kuchuluka kwa m'malo.

HPMC ndi polima madzi sungunuka kuti zimachokera mapadi. Komabe, mosiyana ndi CMC, HPMC imasinthidwa ndi magulu a hydroxypropyl ndi methyl. Magulu a hydroxypropyl (-OCH2CHOHCH3) amalumikizidwa kumagulu a hydroxyl pamsana wa cellulose, pomwe magulu a methyl (-CH3) amamangiriridwa kumagulu a hydroxypropyl. Mlingo wolowa m'malo mwa HPMC umatanthawuza kuchuluka kwa magulu a hydroxypropyl ndi methyl omwe amapezeka pa AGU ya msana wa cellulose. Ma DS a HPMC amatha kuyambira 0.1 mpaka 3.0, ndi ma DS apamwamba akuwonetsa kuchuluka kwa m'malo.

2. Katundu

CMC ndi HPMC ali ndi zinthu zosiyanasiyana zomwe zimawapangitsa kukhala oyenera ntchito zosiyanasiyana. Zina mwazinthu zazikulu za CMC ndi HPMC zalembedwa pansipa:

a. Kusungunuka: CMC imasungunuka kwambiri m'madzi ndipo imapanga mayankho omveka bwino, owoneka bwino. HPMC imasungunukanso kwambiri m'madzi, koma njira zake zitha kukhala zaphokoso kutengera kuchuluka kwa m'malo.

b. Rheology: CMC ndi zinthu za pseudoplastic, zomwe zikutanthauza kuti zimawonetsa kumeta ubweya wa ubweya. Izi zikutanthauza kuti kukhuthala kwa CMC kumachepa pamene kumeta ubweya kumawonjezeka. HPMC, kumbali ina, ndi zinthu za Newtonian, zomwe zikutanthauza kuti kukhuthala kwake kumakhalabe kosalekeza mosasamala kanthu za kumeta ubweya.

c. Zopangira mafilimu: CMC ili ndi zinthu zabwino zopangira mafilimu, zomwe zimapangitsa kuti zikhale zoyenera kugwiritsidwa ntchito popaka ndi mafilimu. HPMC ilinso ndi zinthu zopangira mafilimu, koma mafilimu amatha kukhala osasunthika komanso osavuta kusweka.

d. Kukhazikika: CMC ndi yokhazikika pamitundu yosiyanasiyana ya pH ndi kutentha. HPMC imakhazikikanso pamitundu yambiri ya pH, koma kukhazikika kwake kumatha kukhudzidwa ndi kutentha kwambiri.

3. Ntchito

CMC ndi HPMC amagwiritsidwa ntchito m'mafakitale osiyanasiyana azakudya, zamankhwala, ndi zosamalira anthu. Zina mwazofunikira za CMC ndi HPMC zalembedwa pansipa:

a. Makampani azakudya: CMC imagwiritsidwa ntchito ngati chowonjezera, chokhazikika, ndi emulsifier muzakudya monga ayisikilimu, mavalidwe a saladi, ndi zinthu zophika. HPMC imagwiritsidwanso ntchito ngati thickener ndi stabilizer mu zakudya, koma amagwiritsidwa ntchito kwambiri ngati ❖ kuyanika zinthu confectionery monga maswiti gummy ndi chokoleti.

b. Makampani opanga mankhwala: CMC imagwiritsidwa ntchito ngati binder, disintegrant, ndi mapiritsi ❖ kuyanika pakupanga mankhwala. HPMC amagwiritsidwanso ntchito ngati binder, disintegrant, ndi piritsi ❖ kuyanika wothandizira mu mankhwala formulations.