Hydroxypropyl methylcellulose (HPMC) ndi polima wosunthika yemwe amapeza ntchito zambiri m'mafakitale osiyanasiyana kuphatikiza mankhwala, chakudya, zodzoladzola, ndi zomangamanga. Chimodzi mwazinthu zapadera ndi kuthekera kwake kupanga ma gels pansi pamikhalidwe yapadera. Kumvetsetsa kutentha kwa gelation kwa HPMC ndikofunikira pakuwongolera kugwiritsa ntchito kwake pazinthu zosiyanasiyana.
Chiyambi cha HPMC:
Hydroxypropyl methylcellulose (HPMC) ndi semi-synthetic, inert, viscoelastic polima yochokera ku cellulose. Amagwiritsidwa ntchito ngati thickener, stabilizer, emulsifier, ndi filimu kale chifukwa cha luso lake lopanga mafilimu komanso luso losintha machitidwe amadzimadzi. HPMC ndi sungunuka m'madzi ozizira, ndi yankho mamasukidwe akayendedwe zimatengera zinthu monga molecular kulemera, digiri ya m'malo, ndi ndende.
Njira ya Gelation:
Gelation imatanthawuza njira yomwe yankho limasintha kukhala gel, kusonyeza khalidwe lolimba lokhala ndi mphamvu yosunga mawonekedwe ake. Pankhani ya HPMC, gelation imachitika kudzera munjira yotenthetsera kapena powonjezera zinthu zina monga mchere.
Zomwe Zimakhudza Gelation:
Kukhazikika kwa HPMC: Kuchulukira kwa HPMC nthawi zambiri kumapangitsa kuti madzi asungunuke mwachangu chifukwa cha kuyanjana kwa polima ndi polima.
Kulemera kwa Mamolekyulu: Ma polima apamwamba kwambiri a HPMC amatha kupanga ma gels mosavuta chifukwa chakuchulukirachulukira komanso kuyanjana kwapakati.
Digiri ya Kusinthana: Kuchuluka kwa kusintha, komwe kumasonyeza kukula kwa hydroxypropyl ndi methyl m'malo mwa cellulose msana, kumakhudza kutentha kwa gelation. Madigiri apamwamba olowa m'malo amatha kuchepetsa kutentha kwa gelation.
Kukhalapo kwa Mchere: Mchere wina, monga alkali metal chlorides, ukhoza kulimbikitsa kusungunuka mwa kuyanjana ndi maunyolo a polima.
Kutentha: Kutentha kumagwira ntchito yofunika kwambiri mu gelation. Kutentha kumawonjezeka, maunyolo a polima amapeza mphamvu ya kinetic, zomwe zimathandizira kukonzanso kwa maselo kofunika kuti gel apangidwe.
Kutentha kwa Gelation kwa HPMC:
Kutentha kwa gelation kwa HPMC kumatha kusiyanasiyana kutengera zinthu zingapo zomwe tazitchula kale. Nthawi zambiri, ma gels a HPMC pa kutentha pamwamba pa kutentha kwake kwa gelation, komwe kumakhala kuyambira 50 ° C mpaka 90 ° C. Komabe, izi zitha kusiyanasiyana kutengera mtundu wa HPMC, kuchuluka kwake, kulemera kwa maselo, ndi zina zomwe zimapangidwira.
Kugwiritsa ntchito Gels HPMC:
Mankhwala: Ma gels a HPMC amagwiritsidwa ntchito kwambiri m'mapangidwe amankhwala kuti atulutse mankhwala olamuliridwa, ma topical applications, komanso monga ma viscosity modifiers mumitundu yamadzimadzi.
Makampani a Chakudya: M'makampani azakudya, ma gels a HPMC amagwiritsidwa ntchito ngati zolimbitsa thupi, zolimbitsa thupi, ndi zopangira ma gelling pazinthu zosiyanasiyana monga sosi, zokometsera, ndi mkaka.
Zomangamanga: Ma gels a HPMC amapeza ntchito muzomangamanga monga matope a simenti, komwe amakhala ngati othandizira posungira madzi, kuwongolera magwiridwe antchito komanso kumamatira.
Zodzoladzola: Magelisi a HPMC amaphatikizidwa muzodzoladzola zodzoladzola monga mafuta opaka, mafuta odzola, ndi zinthu zosamalira tsitsi chifukwa chakukula kwawo komanso kukhazikika.
kutentha kwa gelation kwa HPMC kumadalira zinthu zosiyanasiyana kuphatikizapo ndende, kulemera kwa maselo, digiri ya m'malo, ndi kukhalapo kwa zowonjezera monga mchere. Ngakhale kutentha kwa gelation nthawi zambiri kumakhala mkati mwa 50 ° C mpaka 90 ° C, kumatha kusiyanasiyana kutengera zomwe mukufuna. Kumvetsetsa machitidwe a gelation a HPMC ndikofunikira kuti agwiritse ntchito bwino ntchito zosiyanasiyana m'makampani opanga mankhwala, chakudya, zomangamanga, ndi zodzoladzola. Kufufuza kwina pazifukwa zomwe zimathandizira HPMC gelation zitha kupangitsa kuti pakhale mapangidwe apamwamba komanso kugwiritsa ntchito kwaposachedwa kwa polima wosunthika uyu.
Nthawi yotumiza: Mar-28-2024