Hydroxypylpyl (HPMC) ndi polymer yosiyanasiyana yogwiritsidwa ntchito kwambiri m'mafakitale osiyanasiyana, kuphatikizapo zamankhwala osiyanasiyana, zodzoladzola, ndi chakudya. M'zaka zaposachedwa, HPMC yapeza chidwi kwambiri pakugwiritsa ntchito ma hydrogel chifukwa chazinthu zake zapadera monga kupanda biocomat, komanso luso labwino kwambiri.
1. Makina osokoneza bongo:
Ma hymgle okhazikika a HPMG atuluka monga njira zoperekera mankhwala operekera mankhwala obwera chifukwa chokhoza kusokoneza ndi kumasula ochiritsa ochiritsa m'njira yoyenera. Izi ma hydrogel awa amatha kuwonetsa kuti apange makanema apadera posintha mwakusintha kwa polymer, kupaka miyala yodutsa, ndi zokambirana za polly-polymer. Ma hpmc hydrogels agwiritsidwa ntchito popereka mankhwala osiyanasiyana, kuphatikiza anti-okonda othandizira, maantibayotiki, komanso mankhwala osokoneza bongo.
2. Machiritso a bala:
Pazogwiritsa ntchito mankhwala ovulala, hpmc hydrogels imagwira ntchito yofunika kwambiri yolimbikitsa machiritso ndikusinthika kwa minofu. Izi ma hydrogel awa amapanga malo onyowa kuti khungu lichuluke ndi kusamuka, kuwongolera njira yochiritsa mabala. Kuphatikiza apo, mavalidwe opangidwa ndi HPMC ali ndi njira yabwino kwambiri komanso kutsatira mabala osakhazikika, ndikuwonetsetsa kuti ali ndi bedi la bala ndipo akuchepetsa chiopsezo cha matenda.
3. OPHthalmic Mapulogalamu:
HPMC Hydronels imapeza ntchito kwambiri pakupanga ma ophthalmic monga misozi yopanda zojambula. Ma hydrogel awa amapereka mafuta, hydration, komanso nthawi yayitali yokhazikika pamtunda, kupereka mpumulo kuchokera ku zizindikiro zowuma ndi zolemetsa zokuthandizani ovala zovala zapamwamba. Kuphatikiza apo, diso lokhazikitsidwa ndi HPMC limatsikira kuwonetsera ma mucoatheterive, zomwe zimayambitsa kuchuluka kwa mankhwala osokoneza bongo komanso bioavailability.
4..
Mu minofu yamilu ya minofu ndi mankhwala a hpmc hydrogels imagwira ntchito ngati scaffolds forms ndi kusinthika kwa minofu. Izi ma hydrogels zimatsanzira matrix owonjezera a matrix (ECM), amathandizira kuthandizidwa ndi mawonekedwe azomwe akuyenera kukula kwa maselo ndi kusiyanitsa. Pophatikizira ma molekyulu a biotiatictiattiction ndi zinthu zokulira mu hydrogel matrix, spmc-zophatikizira zimapangitsa kuti zisumbuni minofu mu ntchito monga cartilage ndikukonzanso mafupa.
5. Mapangidwe apamwamba:
HPMC Hydrogels imagwiritsidwa ntchito kwambiri pamitundu yapamwamba ngati ma gels, mafuta, ndi zodzola chifukwa cha zovuta za khungu. Izi ma hydrogel awa amapereka mawonekedwe osalala komanso osalala kupangira kwambiri mapangidwe apamwamba akamawathandiza obalalika osakaniza. Kuphatikiza apo, kusintha kwamphamvu kwa HPMC kuwonetsa kumasulidwa kwa othandizira othandizira, kuonetsetsa kuti mwachitali ndi kukhulupirika.
6. Ntchito zamano:
Malingaliro, hpmc hydrogels imapeza mapulogalamu osiyanasiyana kuyambira ku ma denol amalimbikitsa ma denostion. Izi ma hydrogel awa amapereka zomatira bwino pakupanga mano, potero amalimbikitsa kulimba komanso kukwera kwa thupi kwa mano. Komanso, pakamwa pawo ya HPMC yowonetsedwa bwino kwambiri, kutalikirana nthawi yolumikizana ndi mikamwa ndikulimbitsa zofuna zothandizira monga antimickicrobial othandizira ndi fluoride.
7. Kumasulidwa kwa matanthauzidwe:
HPMC Hydronels yakhala ikufufuzidwa kuti ipangidwe yomwe imalamulidwa kuti ibwerere kwa nthawi yayitali. Pophatikizira mankhwala mu ma matrimergrad hpmc matrics, omasulidwa osuta amatha kupangidwira, kulola kusungulumwa mosalekeza ndikuwongolera kwa othandizira kwa nthawi yayitali. Izi zimapangitsa kuti zithandizire monga zabwino monga kuchepetsedwa dorquency, kutsatira kuledzera modekha, komanso zotsatira zoyipa zoyipa.
Hydroxypypyl methylcellulose (hpmc) imagwira kwambiri ntchito zosiyanasiyana mu Hydrogel formictions, makamaka mu mankhwala angapo, makamaka mu ukadaulo, ndi ukadaulo wambiri. Kuphatikiza kwake kwapadera kwa biocomatrict, komanso kuchita zinthu zoyipa zomwe zimapangitsa kuti zikhale zosankha zapamwamba za hydrogel zopangira mankhwala osokoneza bongo, kuchiritsa kwa bala, komanso ntchito zina zamagetsi. Monga kafukufuku wofufuzawu akupitiliza kupita patsogolo, ma hydrogel okhazikika ofunikira akuyembekezeredwa kuti athe kuthana ndi zovuta zovuta kuzachipatala ndi biotechchnology.
Post Nthawi: Meyi-09-2024