Focus on Cellulose ethers

Ubwino wa Pharmaceutical Grade HPMC

Ubwino wa Pharmaceutical Grade HPMC

 

HPMC wakhala mmodzi wa anthu ambiri ntchito excipients mankhwala kunyumba ndi kunja, chifukwa HPMC ali ubwino kuti excipients ena alibe.

1. Kusungunuka kwamadzi

Kusungunuka m'madzi ozizira pansi pa 40 ° C kapena 70% ethanol, makamaka osasungunuka m'madzi otentha pamwamba pa 60 ° C, koma amatha gel osakaniza.

2. Chemical inertness

HPMC ndi mtundu wa non-ioniccellulose ether. Yankho lake lilibe mtengo wa ionic ndipo silimalumikizana ndi mchere wachitsulo kapena ma ionic organic compounds. Choncho, ena excipients sachita nawo pa kukonzekera ndondomeko.

3. Kukhazikika

Ndiwokhazikika ku asidi ndi zamchere, ndipo akhoza kusungidwa kwa nthawi yaitali pakati pa pH 3 ndi 11 popanda kusintha koonekeratu mu viscosity. Yankho lamadzi la HPMC lili ndi anti-mildew ndipo limatha kukhalabe okhazikika pakasungidwe ka nthawi yayitali. Kukhazikika kwabwino kwamankhwala ogwiritsira ntchito HPMC monga chothandizira pokonzekera ndikwabwino kuposa kwamankhwala ogwiritsira ntchito mankhwala achikhalidwe (monga dextrin, starch, etc.).

4. Kusintha mamasukidwe akayendedwe

Osiyana mamasukidwe akayendedwe zotumphukira za HPMC akhoza kusakaniza malinga ndi ziŵerengero zosiyanasiyana, ndi mamasukidwe akayendedwe ake akhoza kusintha malinga ndi malamulo ena, ndipo ali ndi ubale wabwino liniya, kotero chiŵerengero akhoza kusankhidwa malinga ndi zofunika. 2.5 Kagayidwe kachakudya inert HPMC si odzipereka kapena zimapukusidwa mu thupi, ndipo sapereka kutentha, choncho ndi otetezeka mankhwala kukonzekera excipient. .

5. Chitetezo

HPMC nthawi zambiri imatengedwa ngati zinthu zopanda poizoni komanso zosakwiyitsa.

 


Nthawi yotumiza: Jan-27-2023
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