Pharmaceutical grade HPMC

Pharmaceutical grade HPMC Hydroxypropyl methylcellulose is white or milky white, odorless, tasteless, fibrous powder or granule, weight loss on drying does not exceed 10%, soluble in cold water but not hot water, slowly in hot water Swelling, peptization, and forming a viscous colloidal solution, which becomes a solution when cooled, and becomes a gel when heated. HPMC is insoluble in ethanol, chloroform and ether. It is soluble in a mixed solvent of methanol and methyl chloride. It is also soluble in a mixed solvent of acetone, methyl chloride and isopropanol and some other organic solvents. Its aqueous solution can tolerate salt (its colloidal solution is not destroyed by salt), and the pH of 1% aqueous solution is 6-8. The molecular formula of HPMC is C8H15O8-( C10H18O6) -C815O, and the relative molecular mass is about 86,000.

Chemical Specification

Product Grade:

Application

Features and Benefits:

HPMC has excellent water solubility in cold water. It can be dissolved into a transparent solution with a little stirring in cold water. On the contrary, it is basically insoluble in hot water above 60℃ and can only swell. It is a non-ionic cellulose ether. Its solution does not have ionic charge, does not interact with metal salts or ionic organic compounds, and does not react with other raw materials during the preparation process; it has strong anti-sensitivity, and as the degree of substitution in the molecular structure increases, its It is more resistant to allergies and more stable; it is also metabolically inert. As a pharmaceutical excipient, it is not metabolized or absorbed. Therefore, it does not provide heat in medicines and foods. It is low-calorie, salt-free, and non-salt-free for diabetics. Allergenic drugs and foods have unique applicability; it is relatively stable to acids and alkalis, but if the PH value exceeds 2~11 and is affected by higher temperatures or has a longer storage time, its viscosity will decrease; its aqueous solution can provide Surface activity, showing moderate surface tension and interfacial tension values; it has effective emulsification in two-phase systems, can be used as an effective stabilizer and protective colloid; its aqueous solution has excellent film-forming properties, and is a tablet and pill A good coating material. The film coating formed by it has the advantages of colorlessness and toughness. Adding glycerin can also improve its plasticity.

Packaging

The standard packing is 25kg/Fibre drum 

20’FCL: 9 ton with palletized; 10 ton unpalletized.

40’FCL: 18 ton with palletized; 20 ton unpalletized.

Storage:

Store it in a cool, dry place below 30°C and protected against humidity and pressing, since the goods is thermoplastic, storage time should not exceed 36 months.

Safety notes:                                                                          

The above data is in accordance with our knowledge, but don’t absolve the clients carefully checking it all immediately on receipt. To avoid the different formulation and different raw materials, please do more testing before using it.