Advantages of Pharmaceutical Grade HPMC

HPMC has become one of the most widely used pharmaceutical excipients at home and abroad, because HPMC has advantages that other excipients do not have.

1. Water solubility

Soluble in cold water below 40°C or 70% ethanol, basically insoluble in hot water above 60°C, but can gel.

2. Chemical inertness

HPMC is a kind of non-ionic cellulose ether. Its solution has no ionic charge and does not interact with metal salts or ionic organic compounds. Therefore, other excipients do not react with it during the preparation process.

3. Stability

It is relatively stable to acid and alkali, and can be stored for a long time between pH 3 and 11 without obvious change in viscosity. The aqueous solution of HPMC has anti-mildew effect and can maintain good viscosity stability during long-term storage. The quality stability of medicines using HPMC as preparation excipients is better than that of medicines using traditional excipients (such as dextrin, starch, etc.).

4. Adjustable viscosity

Different viscosity derivatives of HPMC can be mixed according to different ratios, and its viscosity can change according to certain rules, and has a good linear relationship, so the ratio can be selected according to requirements. 2.5 Metabolism inert HPMC is not absorbed or metabolized in the body, and does not provide heat, so it is a safe pharmaceutical preparation excipient. .

5. Security

HPMC is generally considered a non-toxic and non-irritating material.