Tuatahi, ko te whakapotonga reo Ingarihi o nga rauemi awhina
MC: Methyl cellulose
EC: ethyl cellulose
HPC: hydroxypropyl cellulose
HPMC: hydroxypropyl methylcellulose
CAP: Cellulose acetate phthalates
HPMCP: hydroxypropyl cellulose phthalates
HPMCAS: hydroxypropyl methyl cellulose acetate succinate
Cmc-na: Konutai carboxymethyl cellulose
MCC: Microcrystalline cellulose
PVP: Povidone
PEG: polyethylene glycol
PVA: Te waipiro polyvinyl
Cms-na: Te konutai carboxymethyl māngaro
PVPP: Povidone hono-whakawhiti
CCNa: konutai konutai carboxymethyl cellulose
Tuarua, ko te whakamahi i etahi rauemi awhina
1. Lactose: papa: whakakī, rawa paura whakakī papa tika; Werohanga: lyophilized protectant
2. Microcrystalline cellulose: papa: paura aki tika papa whakakī; "Apiri maroke"; Ko nga papa kei roto 20% microcrystalline cellulose ka mahi hei whakangawari
3. Methyl cellulose: papa: whakapiri; Kaituku whakatārewatanga: awhina whakatārewatanga; Te whakareri tuku puhoi (whakahaerehia): he mea anga koiwi (ngoikore)
4 konutai carboxymethyl cellulose: papa: whakapiri; Kaituku whakatārewatanga: awhina whakatārewatanga; Te whakareri tuku puhoi (whakahaerehia): he taonga anga koiwi rei hydrophilic
5. Ethyl cellulose: papa: whakapiri (kaore e rewa ki te wai); Te whakareri tuku puhoi (whakahaerehia): he anga angaahi, he mea maataki kiriuhi ranei; Te whakamararatanga totoka: he taonga kawe korekore
6 hydroxypropyl cellulose: papa: whakapiri, rauemi paninga kiriata; Kaituku whakatārewatanga: awhina whakatārewatanga; Te whakareri puhoi (whakahaerehia) te tukunga: he mea anga koiwi kiriwaiwai, he maatete whakakoi pore-pore-whakauru i te membrane microporous.
7. Hydroxypropyl methyl cellulose (hydroxypropyl methyl cellulose): papa: whakapiri, rauemi paninga kiriata; Kaituku whakatārewatanga: awhina whakatārewatanga; Te whakareri tuku puhoi me te whakahaere: he mea anga koiwi kaera hydrophilic, miihini whakakikorua ki te kiriuhi moroiti, he maakuku pore-whakauru.
8. Cellulose acetate phthalates: rauemi enteric
9. Hydroxypropyl cellulose phthalates: nga mea whakauru
10. Hydroxypropyl cellulose acetate succinate: nga mea whakauru
11. Polyvinyl phthalate (PVAP) : he mea whakauru
12. Styrene Maleic acid copolymer (StyMA) : he mea whakarewa intestinal
13. Kapia kiriaku (momo enteric I, II, III), Eudragit L, Eudragit S (i etahi wa ko Eudragit L100 ko Eudragit S 100 ranei) : he mea whakauru
14.Eudragit RL, Eudragit RS: : He taonga kawe korekore
15.Eudragit E (he rite ki te kiriaku IV) : he rauemi polymer wairewa pekitīlia
16. Cellulose acetate: he mea kore e rewa te wai, ka taea te whakamahi mo te paninga, te whakarite ranei i nga papa papu osmotic
17. Polyvinylpyrrolidone (povidone PVP) : papa: whakapiri; Papa: pekitīlia wairewa kiriata paninga rauemi; Pire: pire nifedipine (te whakamararatanga totoka); Kaituku whakatārewatanga: awhina whakatārewatanga;
Te whakamararatanga totoka: he taonga kawe wai-wairewa; Te whakareri puhoi (whakahaerehia) te tukunga: he mea anga koiwi colloid hydrophilic; Te whakarite tukunga puhoi (whakahaerehia): he kaihoko pore-inducing i roto i nga papa kapi kua whakakikoruatia
18. Te waipiro polyvinyl: he kaihoko kiriata: he mea hanga kiriata, he awhina whakatara
19. Te konutai carboxymethyl māngaro: papa: matū whakawehe
20. Povidone hono-whakawhiti: Papa: whakangawari
21. Te konutai konutai carboxymethyl cellulose kua honoa: papa: te kaihoko whakangao
22. He iti-substituted hydroxypropyl cellulose: Papa: whakangawari
23. Te waikawa polylactic: he mea polymer biodegradable, whakamahia mo te whakarite i nga microspheres, nanoparticles, etc
24. Glycerol (ko te sorbitol propylene glycol he tino tata ki te glycerol)
Whakaritenga wai: te whakarewa, te whakarewa werohanga, te awhina aukati, te whakamakuku
Plasticizer i roto i te capsule me te rauemi paninga
Nga hinu, nga punaha tuku whakawhiti: nga kaiwhakatairanga kuhu
Whakanuia te makuku o nga raau taero hydrophobic, te kaiwhakarite pehanga osmotic i roto i te whakaehunga ngako whakauru.
Glycerin gelatin (mo te hinu, suppositories, marara totoka)
25. Glycerin gelatin
Nga pire whakaheke: matrix wairewa-wai
Hupiripi: matrix wairewa-wai
Hinu: Matrix wairewa wai
26. Sodium dodecyl sulfate
Nga whakaehunga, nga hinu: whakaehunga
Kai makuku mo nga takai totoka/whakahinu mo nga papa
kaiwhakarewa
27. Polyethylene glycol (PEG)
Papa: Whakahinuhinu wairewa-wai (PEG 4000, 6000)
Papa: Plasticizer i roto i te whakahaunga paninga kiriata
Kapore: Kapore ngohe kore-hinu wai (PEG 400)
Nga pire whakaheke: Matrix wairewa-wai (PEG 4000, 6000,9300)
Hupiripi: matrix suppository
Aerosol: Te whakarewa huna (PEG 400, 600)
Werohanga: Wairewa (PEG 400, 600)
Whakaritenga wai: Wairewa (PEG 400, 600)
Te whakamararatanga totoka: kawe
Te whakarite tukunga puhoi (whakahaerehia): he kaihoko pore-inducing i roto i nga papa kapi kua whakakikoruatia
Te whakarite mo te tango i te kiri: te whakaniko i te tango i te kiri
28. Poloxam (” zwitterionic “surfactant) I kitea e tetahi hoa tupato he rereketanga i konei, kua whakatikahia inaianei ki” Poloxam “kore-katote surfactant, ehara i te zwitterionic surfactant!
Kaikawe marara totoka, matrix suppository, emulsifier mo te werohanga, whaowhia ranei
He whakarāpopototanga o ngā māngai antiseptic me te bacteriostatic
Hydroxyl benzene ester (koura neper), waikawa benzoic, konutai benzoate, waikawa sorbic, benzalkonium bromide (hou hou), benzalkonium chloride (jie er die), chlorhexidine acetate, benzyl alcohol (mamae rohe) i te wa ano, hono-whakawhiti me te waipiro butyl tuatoru (mamae o te rohe) i te wa ano, te nitrobenzene, te mercury, te thimerosal, te kupenga disinfection, te ortho-phenyl phenol, te phenoxyethanol, te hinu eucalyptus, te hinu hinamona, te hinu pepa, me era atu.
Wha, tikanga whakahoromata
1/ Wehenga huka, whakaehunga ngako mo te werohia ki roto, dextran, konutai pūhaumāota whaowhia, rapa mono me ētahi atu whakahoromata pēhi wera;
2/ Huaora C werohanga, procaine hydrochloride werohia, cortisone acetate werohanga, chloramphenicol pata kanohi i whakahoroa e te rere mamaoa;
3/ Te hinu werohanga, te hinu hinu, te ampoule ma te whakamahi i te tikanga whakamaroke wera maroke;
4/ Te hau rūma Asepsis, te mata tepu whakahaere: te tikanga whakamaoritanga ultraviolet, te tikanga whakakino hau ranei;
5/ Ringa, taputapu aseptic: tikanga whakahoromata matū
6/ Insulin weranga me etahi atu hua koiora: filtration sterilization tikanga
V. Wharite e pa ana
1. Te whārite Noyes-whitney: he whakaahua i te tere memeha o nga raau taero totoka.
2. Te haumākū whanaunga tino nui o te ranunga
hygroscopicity o te paura P68)
3. Utu whakakapingapurakau P87)
4.Poiseuile tātai: whakaahuatia ngā āhuatanga whakaawe o te tātari (whanga P124)
5. Te tātai tātai o te ture isotonic mā te tikanga whakaheke ira mītiwerohia P156)
6. Te tataunga o te uara HLB o te surfactant hanumiwai P178)
Hangarau whakarite e tika ana
1. Microcapsule: tikanga whakamaroke (kotahi, matatini), tikanga whakarewa-kore-whakarewa, te whakarereke i te tikanga o te pāmahana, te tikanga whakamaroke wai, te tikanga whakamaroke rehu, te tikanga whakamaroke rehu, te tikanga whakatārewatanga o te hau, te tikanga whakaahuru atanga, te tikanga whakawhiti radiation
2. Pūhui whakauru: tikanga otinga wai kukū, tikanga huri, tikanga whakamaroke whakatio, tikanga whakamaroke rehu
3. Te whakamararatanga totoka: tikanga whakarewa, tikanga whakarewa, whakarewa - tikanga whakarewa, whakarewa - tikanga whakamaroke rehu, tikanga huri.
4. Liposomes: tikanga werohanga, tikanga marara kiriata kikokore, tikanga whakamararatanga ultrasonic, tikanga whakaetonga whakamuri, tikanga whakamaroke whakatio.
5. Microspheres: emulsification – tikanga whakaora, tikanga whakamaroke rehu, tikanga whakamaroke wai
6. Nanoparticles: polymerization micellar, polymerization emulsion, polymerization interfacial, tikanga whakamaroke wai
7. Pellet: te tikanga whakamaroke koropuke, tikanga whakamaroke rehu, tikanga kohua paninga, tikanga sphericity extrusion, tikanga kaupapa centrifugal, tikanga whakamaroke wai
8 suppository: tikanga rewa wera, tikanga pehi makariri, tikanga pokepoke
9. Te hinu: tikanga huri, tikanga whakarewa, tikanga emulsification
10 te kaihoko kiriata: tikanga hanga kiriata slurry slurry rite, tikanga hanga kiriata pehanga-whakarewa, tikanga hanga kiriata hiato
E whitu, nga taputapu kanohi
1. Microcapsule: gelatin – kāpia Arabic
2. Pūhui whakauru: cyclodextrin
3. Te whakamararatanga totoka: PEG, PVP
4. Liposomes: phospholipid-cholesterol
5. Microspheres: gelatin, albumin, PLA, etc
6. Hupa: pata koukou
7. Hinu: Petroleum jelly, etc
8 kaihoko kiriata: PVA
Waru, he wa torutoru
1. Ko te ampoule kua whakahoroa me waiho kia kaua e neke atu i te 24 haora;
2. Ko te rokiroki o te wai mo te werohanga kaua e neke ake i te 12 haora;
3. Ka oti te whakakorikori i nga werohanga whanui i roto i nga haora 12 i muri i te kohua;
4. Ka oti te whaowhia me te whakarite otinga i roto i te 4 haora i muri i te whakahorotanga
9. Ko nga taonga tirotiro kounga e pa ana ki nga whakaritenga rongoa
1. Papa: nga ahuatanga ahua; He rereke te taumaha; Te pakeke me te pakaruhanga; Te tohu tohu; Te whakakore, te tuku ranei; Te riterite o te ihirangi
2. Mahinga marara: te rite; makuku. Uta rerekē rahinga; whakamātautau hauora; Te arowhai kirikiri
3. Granule: ahua; Rahi matūriki; mate taimaha maroke; rewa; Te rereke o te kawenga
4. Capsule: ahua; makuku. Uta rerekē rahinga; Te whakakore me te whakakore.
5. Whakataka pire: te rereketanga o te taumaha; Te tirotiro tepe wa whakakore, etc.
6. Suppository: ahua; Te rereke o te taumaha; Te wa rewa; Awhe ira whakarewa; Ko te whakamatautau whakangao in vitro me te whakamatautau whakauru in vivo
7. Te raima: te rahi o te matūriki; Te kawenga; Te rohe moroiti; Te ihirangi tarukino matua; Ngā āhuatanga ā-tinana; Whakatairanga; Pūmautanga; Te tuku, te whakauru me te whakauru o nga raau taero ki te hinu.
8. Transdermal papaki: rerekētanga taimaha; Te rereketanga o te waahi; Te riterite o te ihirangi; Tohu tuku, etc.
10. He rereke nga whakamaramatanga
1. Moroiti capsule: he kapopa iti i hangaia ma te takai i te rongoa totoka, wai ranei (e kiia ana ko te kapopeta matua) ki roto i te papanga polymer taiao, waihanga ranei (e kiia ana ko te taonga potae). 1-5000 microns
2. Pellet: e pa ana ki te hinonga porowhita me te diameter iti iho i te 2.5mm i tito mai i nga raau taero me nga mea taapiri.
3. Microsphere: he momo anga anga moroiti moroiti i hangaia ma te whakakore, marara ranei i nga raau taero i roto i te anga o nga rawa polymer, me te rahi o te matūriki i waenga i te 1 me te 250μm.
4. Nanoparticles: matūriki colloidal totoka tito o matū polymeric, ki te rahi matūriki i roto i te whānuitanga o 10 ~ 1000nm.
5. Te kaihoko pire tuku: e pa ana ki nga raau taero totoka, wai ranei me nga matū e tika ana (e mohiotia ana ko te matrix) te ranunga whakawera whakawera, ka taka ki roto i te condensate miscible, te whakapoipoitanga me te hanga pire iti.
Wā tuku: Sep-09-2022