Kedu ụdị polymer bụ HPMC?

HPMC, ma ọ bụ hydroxypropyl methylcellulose, bụ ụdị polymer nke dabeere na cellulose nke a na-ejikarị eme ihe na ụlọ ọrụ ọgwụ, nri, na nlekọta onwe onye. Cellulose bụ polymer eke sitere n'okike nke a na-ahụ n'ime osisi ma bụrụkwa ihe mejupụtara ihe ọkụkụ kachasị n'ụwa. Ọ bụ polymer linear nke nwere monomers glucose jikọtara ya na njikọ β(1→4) glycosidic.

A na-emepụta HPMC site n'ịgbanwe cellulose na kemịkal na otu methyl ma ọ bụ hydroxypropyl. Enwere ike ime mgbanwe ndị a site na ịmeghachi cellulose na reagents kwesịrị ekwesị n'ihu ihe na-eme ka acid. Mmeghachi omume n'etiti cellulose na methyl chloride ma ọ bụ methyl bromide na-emepụta methylcellulose, ebe mmeghachi omume n'etiti cellulose na propylene oxide na-emepụta hydroxypropyl cellulose. A na-emepụta HPMC site na ijikọta mmeghachi omume abụọ a iji webata ma methyl na hydroxypropyl otu n'ime ọkpụkpụ cellulose.

Polymer na-esi na ya pụta nwere usoro mgbagwoju anya nke nwere ike ịdịgasị iche dabere na ogo nnọchi (DS) nke otu methyl na hydroxypropyl. DS na-ezo aka na nkezi ọnụọgụ nke otu hydroxyl nọchiri anya otu anhydroglucose n'ime ọkpụkpụ azụ cellulose. Dịka, HPMC nwere DS nke 1.2 ruo 2.5 maka otu methyl yana 0.1 ruo 0.3 maka otu hydroxypropyl. Ọdịdị nke HPMC na-agbagwoju anya site na eziokwu ahụ bụ na enwere ike kesaa otu methyl na hydroxypropyl n'enweghị usoro n'akụkụ ọkpụkpụ azụ cellulose, na-ebute polymer dị iche iche nwere ọtụtụ ihe onwunwe.

HPMC bụ polymer na-agbaze mmiri nke na-emepụta ihe dị ka gel mgbe a na-agba ya mmiri. Njirimara gelation nke HPMC na-adabere n'ọtụtụ ihe, gụnyere DS, arọ molecular, na ntinye nke polymer. N'ozuzu, HPMC na-etolite gel kwụsiri ike na ọkwa dị elu yana ụkpụrụ DS dị elu. Na mgbakwunye, akụrụngwa gelation nke HPMC nwere ike imetụta pH, ike ionic, na okpomọkụ nke ngwọta.

Njirimara pụrụ iche nke HPMC na-eme ka ọ bụrụ ihe bara uru n'ọtụtụ ngwa. N'ime ụlọ ọrụ na-emepụta ọgwụ, a na-eji HPMC mee ihe dị ka onye na-ekekọta, ihe na-agbasasị, na onye na-emepụta ihe nkiri na mbadamba na capsules. Enwere ike iji ya gbanwee ọnụego ntọhapụ nke ọgwụ site na ụdị usoro onunu ogwu. N'ime ụlọ ọrụ nri, a na-eji HPMC eme ihe dị ka ihe na-agbapụta, stabilizer, na emulsifier. A na-ejikarị ya na nri ndị nwere obere abụba ma ọ bụ obere kalori iji ṅomie udidi na mmetụta ọnụ nke nri abụba dị elu. N'ime ụlọ ọrụ nlekọta onwe onye, ​​a na-eji HPMC eme ihe dị ka ihe na-ekpu mmiri, onye na-emepụta ihe nkiri, na emulsifier na shampoos, lotions, na ngwaahịa ndị ọzọ.

N'ikpeazụ, HPMC bụ polymer nke dabeere na cellulose nke a na-emepụta site na-agbanwe cellulose na kemịkal na otu methyl na hydroxypropyl. Ihe na-esi na polymer pụta bụ mmiri na-agbaze ma nwee usoro mgbagwoju anya nke nwere ike ịdịgasị iche dabere na ogo ngbanwe na nkesa nke methyl na hydroxypropyl. HPMC bụ polima nwere ọtụtụ ngwa na ụlọ ọrụ ọgwụ, nri na nlekọta onwe onye.