Hydroxypropylmethylcellulose (HPMC) E15 bụ ngwa ahịa ọgwụ na-agbanwe agbanwe yana ọtụtụ ojiji na usoro ọgwụ, ịchọ mma na nri. Nke sitere na cellulose eke, ihe nrụpụta cellulose a na-ewu ewu n'ihi njirimara ya pụrụ iche, gụnyere ike ya ịgbanwe viscosity ngwọta, melite profaịlụ ntọhapụ ọgwụ, na ịkwalite nkwụsi ike nhazi.
1.HPMC E15 iwebata:
Hydroxypropyl methylcellulose (HPMC):
HPMC bụ polymer synthetic nke na-enweta site na cellulose, polymer eke dị na mgbidi cell osisi. A na-emepụta ya site n'ịgwọ cellulose na alkali na propylene oxide, na-ebute ogige nwere hydroxypropyl na methoxy substituents. Mgbanwe a na-enye HPMC ihe pụrụ iche, na-eme ka ọ dabara maka ngwa dị iche iche.
2. Hydroxypropyl methylcellulose E15:
HPMC E15 na-ezo aka kpọmkwem na ọkwa HPMC dị elu na viscosity. “E” n'aha ya na-egosi na ọ na-akwado nkọwapụta akọwapụtara na European Pharmacopoeia. A na-ejikarị ọkwa a pụrụ iche na usoro ọgwụ iji nweta njirimara arụmọrụ akọwapụtara.
Ngwa 3.Pharmaceutical:
A. Binders na mbadamba mbadamba:
A na-ejikarị HPMC E15 eme ihe dị ka ihe nkedo na nhazi mbadamba. Njirimara njide ya na-enyere aka ijikọ ihe ọgwụ na-arụ ọrụ (API) na ihe mgbakwunye ọnụ, na-ahụ na mbadamba ụrọ na-adịgide adịgide.
B. Matrix na-emepụta ndị ọrụ na nkwadebe ntọhapụ a na-achịkwa:
HPMC E15 na-etolite matriks dị ka gel mgbe ị na-akpakọrịta na mmiri, na-eme ka ọ dabara maka nhazi ntọhapụ a na-achịkwa ma ọ bụ na-adịgide adịgide. Nke a na-eme ka ntọhapụ ọgwụ na-adịgide adịgide, na-achịkwa ogologo oge, si otú a na-eme ka nnabata ndị ọrịa dịkwuo mma.
C. Ihe mkpuchi ihe nkiri:
A na-eji HPMC E15 dị ka ihe nkiri mbụ maka mkpuchi mbadamba na mbadamba. Ihe nkiri a na-esi na ya na-echebe ọgwụ ahụ site na ihe ndị metụtara gburugburu ebe obibi, na-eme ka ọdịdị ahụ dịkwuo mma ma na-eme ka ọ dị ike.
D. Onye nnọchi anya nkwusioru:
N'ime usoro ọnụ mmiri mmiri, HPMC E15 na-arụ ọrụ dị ka onye na-akwụsịtụ, na-egbochi mbelata irighiri ihe yana hụ na nkesa ọgwụ ahụ n'otu n'otu na mmiri mmiri.
E. Thicker:
Ya viscosity-modifying Njirimara na-eme ka HPMC E15 bara uru dị ka a thickener na mmiri mmiri na ọkara siri ike formulations dị ka gels na creams, na-enyere aka melite ha kwụsie ike na mfe nke ojiji.
F. Nkewa:
N'ụdị ụfọdụ, HPMC E15 nwere ike rụọ ọrụ dị ka ihe na-agbasasị, na-akwalite mbadamba nkume ka ọ daa ngwa ngwa n'ime obere ihe mgbe ị na-ejikọta mmiri, na-akwalite ntọhapụ ọgwụ na absorption.
G. Emulsion stabilizer:
N'ime usoro ndị dị ka ude na lotions, HPMC E15 na-arụ ọrụ dị ka ihe nkwụnye na emulsions, na-egbochi nkewa nkewa na ịbawanye nkwụsi ike nke ngwaahịa ahụ.
H. pellets ntọhapụ na-adịgide adịgide:
A na-ejikwa HPMC E15 mepụta pellet ntọhapụ agbatịgoro nke na-enye profaịlụ ntọhapụ ọgwụ na-achịkwa mgbe ejiri ọnụ na-enye ya.
4. Ngwa ndị ọzọ:
A. Usoro ịchọ mma:
N'ihe ịchọ mma, a na-eji HPMC E15 na ngwaahịa dị iche iche gụnyere ude, lotions na shampoos iji nyere aka melite udidi, nkwụsi ike na n'ozuzu arụmọrụ nke usoro.
B. Ụlọ ọrụ nri:
A na-eji HPMC E15 eme ihe mgbe ụfọdụ na ụlọ ọrụ nri dị ka ihe na-agba, stabilizer ma ọ bụ emulsifier na ngwaahịa ndị dị ka sauces, akwa na ngwa esi nri.
Ụlọ ọrụ mmepụta ihe: C.
N'ime ụlọ ọrụ ihe owuwu, a na-eji HPMC E15 mee ihe dị ka ihe mgbakwunye na ngwaahịa ciment na-eme ka arụ ọrụ dịkwuo mma, nrapado na njide mmiri.
HPMC E15 bụ ihe pụrụ iche na nke dị mkpa nke nwere ngwa dị iche iche, karịsịa na ụlọ ọrụ ọgwụ. Ọrụ ya dị ka onye na-ekekọta, matriks nke mbụ, onye na-ahụ maka mkpuchi ihe nkiri, na ọrụ ndị ọzọ dị iche iche na-eme ka ọ bụrụ isi ihe na-eme ka ọ bụrụ ihe dị mkpa n'ụdị usoro onunu ogwu. Na mgbakwunye na ọgwụ, ojiji ya na-agbatị na ihe ịchọ mma, nri na ụlọ ọrụ ihe owuwu, na-egosipụta ngbanwe ya na mkpa dị na ngwa dị iche iche. Ka nyocha na mmepe na mpaghara ndị a na-aga n'ihu, HPMC E15 nwere ike ịnọgide na-abụ isi ihe na ụlọ ọrụ na-achọ usoro nnyefe ọgwụ ka mma, usoro kwụsiri ike na nkwalite ngwaahịa.
Oge nzipu: Feb-06-2024