HPMC bụ hydroxypropyl methylcellulose, nke bụ ihe na-abụghị ionic cellulose agwakọta ether nke sitere na owu a nụchara anụcha mgbe alkalization, na-eji propylene oxide na methyl chloride dị ka etherification agents, na site na usoro nke mmeghachi omume. Ogo nke nnọchi bụ n'ozuzu 1.2 ~ 2.0. Ngwongwo ya dị iche iche n'ihi oke dị iche iche nke ọdịnaya methoxyl na ọdịnaya hydroxypropyl.
MC bụ methyl cellulose, nke a na-emecellulose ethersite n'iji alkali na-agwọ owu a nụchara anụcha, iji methane chloride dị ka ihe na-eme ka etherification, na ịgafe usoro mmeghachi omume. N'ozuzu, ogo nke nnọchi bụ 1.6 ~ 2.0, na solubility dịkwa iche na ọkwa dị iche iche nke nnọchi. Ọ bụ nke cellulose ether na-abụghị ionic.
Ntụnyere arụmọrụ n'etiti ha abụọ:
(1) Hydroxypropyl methylcellulose na-adị mfe mgbaze na mmiri oyi, ọ ga-enwekwa ihe isi ike na igbari na mmiri ọkụ. Ma gelation okpomọkụ ya na mmiri ọkụ dị nnọọ elu karịa nke methyl cellulose. A na-emeziwanye ihe solubility na mmiri oyi ma e jiri ya tụnyere methyl cellulose. Hydroxypropyl methylcellulose kwụsiri ike na acid na alkali, na ngwọta mmiri ya kwụsiri ike na pH = 2 ~ 12. Caustic soda na mmiri lime enweghị mmetụta dị nta na arụmọrụ ya, mana alkali nwere ike mee ka mgbasa ya dị ngwa ma mee ka viscosity ya dịkwuo elu. Hydroxypropyl methylcellulose kwụsiri ike na nnu nkịtị, ma mgbe ntinye nke ngwọta nnu dị elu, viscosity nke hydroxypropyl methylcellulose ngwọta na-ebuli elu.
Methylcellulose na-agbaze na mmiri oyi, ọ ga-esikwa ike igbari na mmiri ọkụ. Ihe ngwọta ya na-edozi ahụ kwụsiri ike na pH = 3 ~ 12. Ọ nwere ezigbo ndakọrịta na starch, guar gum, wdg na ọtụtụ surfactants. Mgbe okpomọkụ na-erute okpomọkụ gelation, gelation na-eme.
(2) Viscosity nke hydroxypropyl methylcellulose na-ejikọta ya na arọ molekụla ya, na ibu ibu molekụla, otú ahụ ka viscosity dị elu. Okpomọkụ na-emetụtakwa viscosity ya, ka okpomọkụ na-abawanye, viscosity na-ebelata. Otú ọ dị, nnukwu viscosity ya nwere mmetụta okpomọkụ dị ala karịa methyl cellulose. Ngwọta ya kwụsiri ike mgbe echekwara ya na ụlọ okpomọkụ.
Methylcellulose nwere mmetụta dị ukwuu na arụ ọrụ na nrapado nke ngwa agha. “Adhesion” ebe a na-ezo aka na ike nrapado a na-enwe n'etiti ngwa ngwa onye ọrụ na mkpụrụ mgbidi, ya bụ, nkwụsi ike nke ngwa agha ahụ. Nchikota dị elu, nkwụsị nke mgbochi nke ngwa agha dị ukwuu, na ike nke ndị ọrụ na-arụ ọrụ na-arụ ọrụ na-arụkwa ọrụ buru ibu, na ịrụ ọrụ nke ngwa agha adịghị mma. Methyl cellulose adhesion dị na agafeghị oke na ngwaahịa ether cellulose.
(3) Njide mmiri nke hydroxypropyl methylcellulose na-adabere na ego mgbakwunye ya, viscosity, wdg, na ọnụ ọgụgụ njide mmiri ya n'okpuru otu ihe mgbakwunye ahụ dị elu karịa nke methyl cellulose.
Njide mmiri nke methylcellulose na-adabere na ego mgbakwunye ya, viscosity, urughuru mma na ọnụego mgbasa. N'ozuzu, ọ bụrụ na ego mgbakwunye buru ibu, ịdị mma dị ntakịrị, na viscosity dị ukwuu, ọnụ ọgụgụ njide mmiri dị elu. N'ime ha, ọnụ ọgụgụ nke mgbakwunye na-enwe mmetụta kachasị ukwuu na njide mmiri, na ọkwa nke viscosity adịghị adabere kpọmkwem na ọkwa nke njide mmiri. The mgbasa ọnụego tumadi na-adabere n'ókè nke elu mgbanwe nke cellulose ahụ na urughuru fineness. N'ime cellulose ethers dị n'elu, methyl cellulose na hydroxypropyl methyl cellulose nwere ọnụ ọgụgụ njide mmiri dị elu.
(4) Hydroxypropyl methylcellulose nwere ike ịgwakọta ya na mmiri-soluble polymer ogige na-etolite a edo na elu viscosity ngwọta. Dị ka mmanya polyvinyl, starch ether, akwukwo nri chịngọm, wdg. Nkwenye nke hydroxypropyl methylcellulose na ngwa agha na-ewu dị elu karịa nke methylcellulose.
Hydroxypropyl methylcellulose nwere nguzogide enzyme dị mma karịa methylcellulose, na ngwọta ya adịkwaghị ka ọ ga-emebi site na enzymes karịa methylcellulose.
Mgbanwe na okpomọkụ nwere ike imetụta njigide mmiri nke methyl cellulose. N'ozuzu, ka okpomọkụ dị elu, na-akawanye njọ njigide mmiri. Ọ bụrụ na okpomọkụ nke ngwa agha gafere 40 Celsius, njide mmiri nke methyl cellulose ga-ebelata nke ukwuu, na-emetụta nrụnye ngwa ngwa. Mgbe okpomọkụ dị oke elu, gbalịa ịhọrọ hydroxypropyl methylcellulose.
Oge nzipu: Dec-20-2022