Focus on Cellulose ethers

Hypromellose ọ na-emerụ ahụ?

Hypromellose ọ na-emerụ ahụ?

Hypromellose, nke a makwaara dị ka hydroxypropyl methylcellulose, bụ polymer synthetic, inert, na mmiri-soluble nke a na-ejikarị na ụlọ ọrụ dị iche iche. A na-ejikarị ya eme ihe dị ka ihe mgbakwunye nri, thickener, emulsifier, yana dị ka ihe na-emepụta ọgwụ na-emepụta mbadamba nkume, capsules, na nkwadebe ophthalmic. N'isiokwu a, anyị ga-enyocha nchekwa nke hypromellose na mmetụta ahụike ya.

Nchekwa nke Hypromellose

A na-ewerekarị Hypromellose dị mma maka oriri site n'aka ndị ọrụ nchịkwa dị iche iche, gụnyere United States Food and Drug Administration (FDA), European Safety Safety Authority (EFSA), na Joint FAO/WHO Expert Committee on Food Additives (JECFA). A na-ekewa ya dị ka ihe mgbakwunye nri GRAS (nke a na-ahụkarị dị ka nchekwa) site na FDA, nke pụtara na ọ nwere ogologo akụkọ ihe mere eme nke iji nri na-adịghị mma ma eleghị anya ọ ga-emerụ ahụ mgbe ejiri ya mee ihe.

N'ụlọ ọgwụ, a na-eji hypromellose eme ihe n'ọtụtụ ebe dị ka ihe nchekwa dị mma na nke anabatara nke ọma. Edepụtara ya na US Pharmacopeia ma jiri ya mee ihe n'ichepụta ụdị ọgwụgwọ siri ike na nke mmiri mmiri. A na-ejikwa ya dị ka mmanu ophthalmic ma na-ewere ya dị mma maka iji lenses kọntaktị, anya mmiri artificial na ngwaahịa anya ndị ọzọ.

Nnyocha e mere egosiwo na hypromellose nwere obere toxicity nke anụ ahụ anaghị etinye ya n'ahụ. Ọ na-agafe na eriri afọ na-agbajighị, a na-esikwa ya na nsị. A na-ewerekwa Hypromellose dị mma maka iji ya mee ihe n'ime ụmụ nwanyị dị ime na ndị na-enye nwa ara, yana ụmụaka, na-enweghị mmetụta ọjọọ amaghi ama.

Mmetụta ahụike nwere ike ime nke Hypromellose

Ọ bụ ezie na a na-ewerekarị hypromellose dị mma maka oriri, enwere ụfọdụ mmetụta ahụike nwere ike ịtụle.

Mmetụta Gastrointestinal

Hypromellose bụ polymer soluble mmiri nke na-amịkọrọ mmiri ma mepụta ihe dị ka gel mgbe ọ na-abanye na mmiri mmiri. Nke a nwere ike ịkpata ịba ụba viscosity na tract gastrointestinal, nke nwere ike belata oge nnyefe nri site na usoro nri nri. Nke a nwere ike ibute afọ ntachi, afọ ntachi, na ahụ erughị ala n'ụfọdụ ndị mmadụ, ọkachasị ma ọ bụrụ na ejiri ya buru ibu.

Mmeghachi omume nfụkasị ahụ

Mmeghachi omume nfụkasị na hypromellose dị ụkọ, mana ha nwere ike ime. Mgbaàmà nke mmeghachi ahụ nfụkasị ahụ nwere ike ịgụnye hives, itching, ọzịza nke ihu, egbugbere ọnụ, ire, ma ọ bụ akpịrị, ike iku ume, na anaphylaxis (mmeghachi omume nfụkasị siri ike, nke nwere ike ime ndụ). Ọ bụrụ na ị nweta nke ọ bụla n'ime mgbaàmà ndị a mgbe ị risịrị hypromellose, chọọ nlekọta ahụike ozugbo.

Iwe iwe anya

A na-ejikarị Hypromellose mee ihe dị ka mmanu anya na mmepụta nke anya anya na nkwadebe anya ndị ọzọ. Ọ bụ ezie na a na-ewere ya na ọ dị mma maka iji anya, ụfọdụ ndị nwere ike ịnweta mgbakasị anya ma ọ bụ mmetụta ọjọọ ndị ọzọ. Mgbaàmà nke mgbakasị ahụ anya nwere ike ịgụnye ọbara ọbara, itching, ọkụ, na ndọkasị.

Mmekọrịta ọgwụ

Hypromellose nwere ike iji ọgwụ ụfọdụ na-emekọrịta ihe, ọkachasị ndị chọrọ obere pH gburugburu maka nnabata. Nke a bụ n'ihi na hypromellose na-etolite ihe dị ka gel mgbe ọ na-abanye na mmiri mmiri, nke nwere ike belata mgbasa na absorption nke ọgwụ. Ọ bụrụ na ị na-aṅụ ọgwụ ọ bụla, gụnyere ndenye ọgwụ ma ọ bụ ọgwụ ndị na-ere ahịa, ọ dị mkpa ka gị na onye na-ahụ maka ahụike gị kpọtụrụ tupu ị were hypromellose ma ọ bụ ihe mgbakwunye nri ọ bụla.

Mmechi

A na-ahụta hypromellose dị mma maka ndị ọrụ nchịkwa dị iche iche. A na-eji ya eme ihe n'ọtụtụ ebe dị ka ihe mgbakwunye nri, thickener, na emulsifier, yana mgbakwunye ọgwụ na-emepụta mbadamba mbadamba, capsules, na nkwadebe ophthalmic.


Oge nzipu: Mar-04-2023
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