Focus on Cellulose ethers

Hypromellose usoro ọrụ

Hypromellose bụ hydrophilic, polima na-abụghị ionic nke a na-eji n'ọtụtụ ọgwụ na ngwa ọgwụ, gụnyere dị ka ihe na-eme mmanu na viscosity n'ime mmiri anya, dị ka onye na-ekpuchi ihe na mbadamba na capsules, yana dịka onye na-ahapụ ya na ọgwụ. usoro nnyefe. Usoro nke hypromellose na-ejikọta ya na ihe ndị pụrụ iche nke physicochemical, gụnyere ikike ijide mmiri dị elu na ike ịmepụta gels n'ihu mmiri.

  1. Mmanya mmanye: N'ihe gbasara anya hypromellose, usoro izizi nke ime ihe bụ mmanu mmanu. Mgbe etinyere ya n'elu anya, hypromellose na-etolite ihe nkiri dị mkpa nke na-enyere aka belata esemokwu n'etiti nkuchianaya na cornea, si otú ahụ na-ebelata nkụ, ọbara ọbara, na mgbakasị ahụ. Mmetụta mmanye a bụ n'ihi nnukwu mmiri na-ejide mmiri nke hypromellose, nke na-enye ya ohere ịmịnye ma na-ejide mmiri site na ihe nkiri akwa mmiri, na ikike ya ịgbasa n'elu anya.
  2. Viscosity: Hypromellose nwekwara ike ime ka viscosity nke ngwọta dịkwuo mma, nke nwere ike ime ka njide ha dị n'elu anya ma mee ka oge kọntaktị ha na anya. Mmetụta a dị mkpa karịsịa n'ihe banyere ọdịda anya, n'ihi na ọ nwere ike inye aka mee ka ọgwụgwọ ọgwụgwọ nke ọgwụ ahụ dịkwuo elu.
  3. Mkpuchi: Hypromellose na-ejikarị dị ka ihe mkpuchi na mbadamba na capsules. N'ime ngwa a, ọ na-etolite mkpuchi nchebe gburugburu ọgwụ ahụ nke nwere ike inye aka ịchịkwa ọnụego nke ntọhapụ ọgwụ ma chebe ọgwụ ahụ site na mmebi nke afọ ma ọ bụ eriri afọ. Usoro nke hypromellose na ọnọdụ a metụtara ikike ya ịmepụta ihe mgbochi n'etiti ọgwụ na gburugburu ebe obibi, nke nwere ike inye aka melite nkwụsi ike na bioavailability nke ọgwụ.
  4. Ntọhapụ na-adịgide adịgide: Hypromellose nwekwara ike iji dị ka onye na-ahapụ ya na sistemu nnyefe ọgwụ. N'ime ngwa a, a na-eji ya na-emepụta matriks dị ka gel nke nwere ike ịchịkwa ntọhapụ nke ọgwụ ahụ ruo ogologo oge. Usoro nke hypromellose na-eme n'ọnọdụ a metụtara ikike ya ịmepụta netwọk nke njikọ hydrogen nke nwere ike ijide ụmụ irighiri ọgwụ na ịchịkwa ntọhapụ ha.

\ usoro nke hypromellose na-ejikọta ya na ihe ndị pụrụ iche nke physicochemical, nke na-agụnye ikike ijide mmiri dị elu, ike ịmepụta gels n'ihu mmiri, na ikike ya ịbawanye viscosity nke ngwọta. Ngwongwo ndị a na-eme ka ọ bụrụ polymer dị iche iche na nke a na-ejikarị eme ihe na ụlọ ọrụ ọgwụ na ọgwụ, karịsịa na mmepe nke anya mmiri, mbadamba nkume, capsules, na usoro nnyefe ọgwụ.

 


Oge nzipu: Mar-04-2023
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