Hydroxypropylcellulose (HEC) bụ ihe sitere na cellulose, polymer eke dị na mgbidi cell osisi. A na-eji HPC eme ihe n'ọtụtụ ụlọ ọrụ dị iche iche dị ka ọgwụ, ihe ịchọ mma na ụlọ ọrụ nri n'ihi imepụta ihe nkiri na ihe na-eme ka ọ dị mma. Njikọ nke hydroxypropylcellulose gụnyere ọtụtụ usoro na usoro ahụ nwere ike ịdị mgbagwoju anya.
Okwu mmalite nke hydroxypropylcellulose:
1. Iji cellulose dị ka mmalite ihe:
Isi mmalite nke cellulose bụ ihe ọkụkụ dị ka pulp osisi ma ọ bụ owu. Cellulose bụ polymer linear nke mejupụtara nkeji glucose jikọtara ya na njikọ β-1,4-glycosidic. Ọ nwere oke polymerization, yana ọtụtụ puku nkeji glucose na-akpụ agbụ ogologo.
2. Mmeghachi omume etherification:
Njikọ nke hydroxypropylcellulose gụnyere iwebata otu hydroxypropyl n'ime ọkpụkpụ azụ cellulose site na etherification. Mmeghachi omume a na-agụnyekarị iji propylene oxide dị ka onye na-ahụ maka alkylating.
Cellulose + propylene oxide → alkali-catalyzed hydroxypropyl cellulose + ngwaahịa cellulose + propylene oxide alkali-catalyzed hydroxypropyl cellulose + site-ngwaahịa
Isi catalysis dị mkpa iji kwalite mmeghachi omume n'etiti otu cellulose hydroxyl na propylene oxide. A na-eme usoro a n'okpuru ọnọdụ a na-achịkwa iji hụ na ngbanwe achọrọ (DS) nke otu hydroxypropyl na agbụ cellulose.
3. Hydroxypropylation:
Hydroxypropylation gụnyere mgbakwunye nke otu hydroxypropyl na ọkpụkpụ azụ cellulose. Mgbanwe a na-eme ka ọ dịkwuo mma na ihe ndị ọzọ a na-achọsi ike na polymer cellulosic. A na-ejikwa nlezianya na-achịkwa ọnọdụ mmeghachi omume, gụnyere okpomọkụ, nrụgide na oge mmeghachi omume iji nweta njirimara ngwaahịa achọrọ.
4. Ọgwụgwọ Alkali:
Mgbe hydroxypropylation gasịrị, a na-ejikarị ọgwụgwọ alkaline mee ihe iji kpochapụ adịghị ọcha acid ọ bụla fọdụrụnụ ma mezie pH nke ngwakọta mmeghachi omume. Nzọụkwụ a dị oké mkpa maka usoro nchacha na-esote.
5. Usoro nchacha:
Mgbe mmeghachi omume etherification gasịrị, a na-eme ọtụtụ usoro nchacha iji nweta hydroxypropylcellulose dị ọcha. Usoro ndị a nwere ike ịgụnye:
Na-asa: saa ngwakọta mmeghachi omume iji wepụ ihe ndị fọdụrụnụ, ihe ndị na-emepụta ihe na cellulose na-emeghị eme.
Filtration: A na-eji nzacha kewapụ ihe adịghị ọcha siri ike na ngwakọta mmeghachi omume.
ihicha: A na-akpọzi hydroxypropyl cellulose dị mmiri iji wepụ mmiri ọ bụla fọdụrụnụ.
6. njikwa arọ nke molikula:
Enwere ike ịchịkwa ịdị arọ nke hydroxypropylcellulose n'oge njikọ iji kwado njirimara ya na ngwa ndị akọwapụtara. A na-enweta nke a site n'ịgbanwe ọnọdụ mmeghachi omume, dị ka ọnụọgụ nke reagents na oge mmeghachi omume.
Mmepụta ụlọ ọrụ:
1. Usoro na-adịte aka ma ọ bụ na-aga n'ihu:
Enwere ike ịme mmepụta nke hydroxypropyl cellulose na nhazi ma ọ bụ na-aga n'ihu. Usoro nhazi ahụ dabara adaba maka mmepụta obere obere, ebe usoro na-aga n'ihu na-adaba adaba maka mmepụta ihe dị ukwuu.
2. njikwa mma:
A na-emejuputa usoro njikwa mma n'oge ọ bụla nke usoro mmepụta iji hụ na ịdị ọcha na ịdị ọcha nke ngwaahịa ikpeazụ. A na-eji usoro nyocha dị ka chromatography, spectroscopy na rheological ọmụmụ iji nyochaa isi ihe dị ka ogo nke nnọchi, ịdị arọ molecular na ịdị ọcha.
Ngwa nke Hydroxypropyl Cellulose:
1. Ụlọ ọrụ na-emepụta ọgwụ:
A na-eji Hydroxypropylcellulose eme ihe n'ọtụtụ ebe na nkwadebe ọgwụ dị ka ihe nkedo, nke na-agbasa na onye na-achịkwa ntọhapụ. Ndakọrịta ya na ụdị ọgwụ dịgasị iche iche na inertness ya na-eme ka ọ bụrụ ihe pụrụ iche.
2. Ụlọ ọrụ ịchọ mma:
N'ụlọ ọrụ ịchọ mma, a na-eji hydroxypropylcellulose na-emepụta ngwaahịa nlekọta ntutu isi, ude anụ ahụ na ngwaahịa nlekọta onwe onye ndị ọzọ. Ihe ndị na-emepụta ihe nkiri ya na-eme ka ọ baa uru na ngwaahịa nlekọta ntutu isi.
3. Ụlọ ọrụ nri:
N'ime ụlọ ọrụ nri, a na-eji hydroxypropylcellulose mee ihe dị ka onye na-eme ihe na-ekpo ọkụ na gelling. A na-achọta ya n'ụdị nri dị iche iche ma na-enyere aka melite ọdịdị na nkwụsi ike ha.
Njikọ nke hydroxypropylcellulose gụnyere etherification nke cellulose site na mgbakwunye nke otu hydroxypropyl. A na-emekarị mmeghachi omume site na ntọala, na-esote usoro nchacha iji nweta ngwaahịa dị oke ọcha. Enwere ike ịrụpụta mmepụta ụlọ ọrụ site na batch ma ọ bụ na-aga n'ihu na usoro njikwa mma siri ike. Hydroxypropylcellulose nwere ngwa dịgasị iche iche na ụlọ ọrụ ọgwụ, ịchọ mma na nri n'ihi ihe pụrụ iche ya na ike ya. Ọganihu na-aga n'ihu nke usoro mmepụta na mmepe nke ngwa ọhụrụ na-emesi ike
Oge nzipu: Dec-26-2023