Hydroxypropyl Methylcellulose (HPMC) bụ cellulose ether gbanwere nke a na-ejikarị na nkwadebe ọgwụ, ihe mgbakwunye nri, ihe ụlọ, ihe ịchọ mma na ubi ndị ọzọ. HPMC nwere thickening, film-akpụ, adhesion na ndị ọzọ Njirimara. Mmekọrịta dị n'etiti viscosity na itinye uche nke ngwọta mmiri ya dị oke mkpa maka ngwa dị iche iche.
Viscosity e ji mara nke HPMC aqueous ngwọta
Njiri mara
HPMC na-etolite ihe ngwọta translucent ma ọ bụ translucent viscous mgbe agbazere na mmiri. A na-emetụta viscosity ya ọ bụghị naanị site na ntinye nke HPMC, kamakwa site na ihe ndị dị ka ịdị arọ molekụla, ụdị nnọchi na ọnọdụ okpomọkụ.
Ibu molecular: Ka ibu molekụla buru ibu nke HPMC, ka viscosity ngwọta dị elu. Nke a bụ n'ihi na macromolecules na-etolite usoro mgbagwoju anya dị mgbagwoju anya na ngwọta, nke na-eme ka esemokwu dị n'etiti ụmụ irighiri ihe.
Ụdị nnọchi: Oke nke methoxy na hydroxypropoxy na-emetụta solubility na viscosity nke HPMC. N'ozuzu, mgbe methoxy ọdịnaya dị elu, solubility nke HPMC ka mma na viscosity nke ngwọta dịkwa elu.
Mmekọrịta dị n'etiti itinye uche na viscosity
Ogbo ngwọta gbazee:
Mgbe ịta ahụhụ nke HPMC dị ala, mmekọrịta dị n'etiti ụmụ irighiri ihe na-esighi ike na ngwọta na-egosipụta njirimara mmiri Newtonian, ya bụ, viscosity bụ isi na-adabere na ọnụ ọgụgụ shear.
N'oge a, viscosity nke ngwọta na-abawanye linearly na-amụba itinye uche. Enwere ike igosipụta njikọ ahịrị a site na nha viscosity dị mfe:
itinye uche (%) | Viscosity (mPa·s) |
0.5 | 100 |
1.0 | 300 |
2.0 | 1000 |
5.0 | 5000 |
10.0 | 20000 |
Enwere ike ịhụ site na data na viscosity nke ngwọta mmiri HPMC na-abawanye ụba na mmụba nke ntinye uche. Ọganihu a ga-apụta na eserese dị ka akụkụ na-arị elu na-arị elu, ọkachasị n'akụkụ ebe itinye uche dị elu.
Ihe ndị na-emetụta
Mmetụta okpomọkụ
Okpomọkụ nwere mmetụta dị ukwuu na viscosity nke ngwọta HPMC. N'ikwu okwu n'ozuzu, mmụba nke okpomọkụ na-ebelata viscosity nke ngwọta. Nke a bụ n'ihi na ọ̀tụ̀tụ̀ ikpo ọkụ na-abawanye na-akpata mmụba nke mmegharị molekụla ma na-ebelata mmekọrịta dị n'etiti agbụ molekụla, si otú ahụ na-ebelata viscosity.
Mmetụta ọnụ ọgụgụ shear
Maka ihe ngwọta HPMC dị elu, viscosity na-emetụtakwa ọnụ ọgụgụ shear. Na ọnụ ọgụgụ dị elu nke shea, nhazi nke ụdọ molekụla na-agbanwe agbanwe ma na-ebelata esemokwu dị n'ime ya, na-eme ka viscosity dị ala nke ngwọta. A na-akpọ ihe a na-akpọ shear thinning.
Ngwa
N'ime nkwadebe ọgwụ, a na-ejikarị HPMC eme ihe na mkpuchi mbadamba, ụdị ntọhapụ na-adịgide adịgide, na ihe ndị na-ebu ibu. Ịghọta ka viscosity nke HPMC aqueous ngwọta si agbanwe na itinye uche dị oké mkpa maka ịmepụta usoro ọgwụ kwesịrị ekwesị. Dịka ọmụmaatụ, na mkpuchi mbadamba nkume, ntinye HPMC kwesịrị ekwesị nwere ike hụ na mmiri mkpuchi ahụ nwere viscosity zuru oke iji kpuchie elu mbadamba nkume, ebe ọ bụghị nke dị elu na-esiri ike ijikwa ya.
N'ụlọ ọrụ nri, a na-eji HPMC eme ihe dị ka thickener na stabilizer. Ịghọta mmekọrịta dị n'etiti itinye uche na viscosity nwere ike inyere aka chọpụta ntinye kachasị mma iji hụ na uto na udidi nke nri.
The viscosity nke HPMC aqueous ngwọta nwere ịrịba mma mmekọrịta na ịta. Ọ na-egosi mmụba n'ahịrị na ọkwa ngwọta dilute yana mmụba dị elu na ntinye uche dị elu. Njirimara viscosity a dị oke mkpa n'ụdị ngwa ụlọ ọrụ dị iche iche, yana nghọta na ịchịkwa mgbanwe viscosity nke HPMC bụ ihe dị oke mkpa maka njikarịcha usoro yana nkwalite ogo ngwaahịa.
Oge nzipu: Jul-08-2024