HPMC (Hydroxypropyl Methylcellulose) bụ kemịkalụ kemịkalụ nke a na-ejikarị na ọgwụ, nri na ụlọ ọrụ. Ọrụ ya na mpaghara dị iche iche bụ tumadi n'ihi ọmarịcha anụ ahụ na kemịkal ya. The isi Njirimara nke HPMC na-agụnye ezigbo mmiri solubility, gelling, ndim, emulsification na film-akpụ Njirimara, n'ihi ya, ọ nwere ike na-egwu dị iche iche nke ọrụ dị iche iche ngwa.
1. Chemical Njirimara na Ọdịdị nke HPMC
HPMC bụ polymer synthetic nke ọkara nke enwetara site na mgbanwe kemịkalụ nke cellulose. N'ime usoro kemịkalụ ya, ụfọdụ hydroxyl dị iche iche na-anọchi methyl na hydroxypropyl dị iche iche, nke na-agbanwe mmiri solubility na mgbaze ọnọdụ okpomọkụ nke cellulose eke. Solubility nke HPMC dịgasị iche n'ihi ogo nke nnọchi ya (DS) na nkesa nke nnọchi. Enwere ike ịgbaze ya na mmiri oyi iji mepụta ngwọta colloidal na-enweghị atụ na nke kwụsiri ike, ebe ọ ga-agbaze na mmiri ọkụ iji mepụta gel. Ihe onwunwe a na-enye ya ọrụ dị iche iche na-arụ ọrụ na okpomọkụ dị iche iche.
2. Ngwa nke HPMC na pharmaceuticals
HPMC nwere ngwa dị mkpa na mpaghara ọgwụ, ọkachasị na mbadamba mbadamba na nkwadebe capsule. Nke a bụ ụfọdụ isi ọrụ HPMC na ọgwụ:
Ihe mkpuchi mbadamba: HPMC na-ejikarị dị ka ihe mkpuchi maka mbadamba nkume. Ọ nwere ike ịmepụta ihe nkiri nchebe iji chebe ọgwụ ahụ site na mmiri, ọkụ na ikuku, si otú ahụ gbasaa ndụ ndụ nke ọgwụ ahụ. Tụkwasị na nke ahụ, ihe nkiri na-emepụta ihe nkiri nke HPMC na-enyere ya aka ikpuchi mbadamba nkume ndị ahụ n'otu n'otu, na-eme ka ntọhapụ nke ọgwụ ahụ na tract gastrointestinal na-esiwanye ike ma na-achịkwa ya.
Ihe ntọhapụ a na-achịkwa: A na-ejikarị HPMC mee mbadamba mbadamba ihe na-achịkwa yana capsules na-adịgide adịgide. N'ihi na ọ na-aza na mmiri ma na-emepụta akwa gel, ọ nwere ike ịchịkwa ọnụego ntọhapụ nke ọgwụ ahụ. Ka oge na-aga, mmiri na-eji nwayọọ nwayọọ abanye n'ime ya, gel oyi akwa nke HPMC ji nwayọọ nwayọọ gbasaa, na-ahapụkwa ọgwụ ahụ. Usoro a nwere ike ịgbatị oge ntọhapụ nke ọgwụ ahụ nke ọma, belata ugboro ole ọgwụ, ma melite nnabata onye ọrịa.
Ihe nchikota na ihe mgbakwunye: N'ụdị usoro ọgwụ, enwere ike iji HPMC dị ka ihe nkedo iji kwalite ike igwe mbadamba. Na mgbakwunye, n'ihi mma mmiri na mkpakọ ya, HPMC nwekwara ike iji dị ka ihe excipient nyere aka nkwadebe ụdị mbadamba nkume nke edo udi n'oge tableting.
3. Ngwa nke HPMC na nri
N'ụlọ ọrụ nri, a na-ejikarị HPMC eme ihe dị ka mgbakwunye nri n'ọrụ dị iche iche dị ka thickener, emulsifier na stabilizer. Ngwongwo na-adịghị egbu egbu, isi na enweghị isi na HPMC na-eme ka ọ bụrụ nchekwa na ntụkwasị obi na ngwa nri dị iche iche.
Thickener: HPMC nwere ike ịmepụta usoro netwọkụ na mmiri site na yinye polymer ya, si otú ahụ na-abawanye viscosity nke ngwọta. A na-eji akụrụngwa a eme ihe na ofe, ofe, na condimenti iji meziwanye udidi nri ma mee ka ọ dị ogologo na otu.
Emulsifier na stabilizer: HPMC nwere ike inye aka emulsify mmanụ na mmiri, zere stratification nke mmiri na mmanụ na nri, ma na-edobe edo edo nke emulsion. Dịka ọmụmaatụ, na nri dị ka uwe salad na ice cream, mmetụta emulsifying ya na-eme ka udidi ngwaahịa ahụ dị nro ma kwụsie ike. Na mgbakwunye, HPMC nwekwara ike iji dị ka stabilizer na nri iji gbochie nri ịwụda ma ọ bụ nkewa n'oge nchekwa.
Ihe ndochi abuba: Enwere ike iji HPMC mee ihe dika ihe nnochita abuba nwere obere kalori iji belata abuba n'ime nri nwere kalori. N'ime usoro nri na-enweghị abụba ma ọ bụ abụba na-enweghị abụba, Njirimara gelling nke HPMC na-enyere ya aka ime ka uto na udidi nke abụba, na-egbo mkpa ndị na-azụ ahịa maka nri nwere obere kalori.
4. Ngwa nke HPMC na-ewu na ụlọ ọrụ
HPMC na-arụkwa ọrụ dị mkpa n'ime ihe owuwu na ụlọ ọrụ mmepụta ihe, karịsịa na mmepụta ihe ụlọ na mkpuchi.
Onye na-ejide mmiri na mmiri na ciment na ngwaahịa gypsum: N'ime ciment dabeere na ihe ndị dabeere na gypsum, ndị na-agba ume na mmiri na-ejide mmiri nke HPMC dị mkpa karịsịa. HPMC nwere ike igbochi ịla azụ na ịdaba site n'ịbawanye viscosity na ngwakọta. Tụkwasị na nke ahụ, HPMC nwere ike ịgbatị oge njide mmiri n'ime ihe ahụ ma zere ihicha ngwa ngwa, si otú ahụ na-emeziwanye arụmọrụ n'oge a na-ewu ma na-eme ka ike ikpeazụ na ike nke ihe ahụ dịkwuo mma.
Ihe nkiri bụbu na thickener na mkpuchi: N'ime mkpuchi ụlọ na eserese, a na-ejikarị HPMC eme ihe dị ka ihe na-ekpu mmiri na ihe nkiri mbụ. Ọ nwere ike ịchịkwa mmiri na viscosity nke mkpuchi ahụ, na-eme ka ọ dị mfe itinye ma ghara ịdaba n'oge a na-ewu ụlọ. N'otu oge ahụ, ihe nkiri na-emepụta ihe nkiri nke HPMC na-emekwa ka mkpuchi ahụ na-ekpuchi elu nke mkpụrụ ahụ, na-eme ka oyi akwa dị mma na nke siri ike, na-emeziwanye ihe ịchọ mma na nchebe nke mkpuchi ahụ.
Ihe mgbakwunye na ngwaahịa seramiiki na rọba: N'ime ụlọ ọrụ seramiiki na plastik, enwere ike iji HPMC mee mmanụ mmanu, ihe nkiri mbụ na onye ntọhapụ. Ọ nwere ike imeziwanye mmiri nke ihe ahụ n'oge usoro ịkpụzi, na-eme ka ọ dị mfe ịrụ ọrụ na ịkpụzi. Na mgbakwunye, HPMC nwekwara ike ịmepụta elu dị larịị, belata ịrapara ebu, ma melite mkpụrụ nke ngwaahịa ahụ.
5. Nchekwa gburugburu ebe obibi na nkwado nke HPMC
HPMC bụ ihe sitere na cellulose eke, yabụ na ọ nwere ike imebi ihe na gburugburu ebe obibi. N'ọnọdụ dị ugbu a nke akwụkwọ ndụ akwụkwọ ndụ na mmepe na-adigide, ihe onwunwe nke HPMC na-eme ka ọ bụrụ nhọrọ ihe onwunwe na gburugburu ebe obibi. N'iji ya na polymers sịntetik ndị ọzọ, HPMC adịghị ebute oke mmetọ na gburugburu ebe obibi, na ngwaahịa ire ere na gburugburu ebe obibi adịghịkwa emerụ ahụ na gburugburu ebe obibi.
Dị ka a multifunctional ihe, HPMC na-ọtụtụ ebe na-eji n'ọtụtụ ubi dị ka pharmaceuticals, nri, ewu na ụlọ ọrụ. Ngwongwo anụ ahụ na kemịkal ya dị mma na-enyere ya aka igosipụta ọtụtụ ọrụ n'okpuru ọnọdụ okpomọkụ dị iche iche, iru mmiri na ọnọdụ, dị ka ịgbatị, njide mmiri, mmepụta ihe nkiri na ntọhapụ a na-achịkwa. Site n'ịbawanye ihe achọrọ maka ahụike, nchekwa na nchekwa gburugburu ebe obibi, ikike ngwa nke HPMC na mpaghara ọhụrụ ga-aga n'ihu na-abawanye n'ọdịnihu. Ma na mmepe nke mbadamba ọgwụ na-achịkwa-achịkwa ma ọ bụ na ntinye nke ihe eji ewu ụlọ na gburugburu ebe obibi, HPMC egosila nnukwu atụmanya.
Oge nzipu: Sep-19-2024