Hydroxypropyl methylcellulose (HPMC) bụ ihe dị mkpa na-edozi mmiri nke a na-ejikarị eme ihe na ụlọ ọrụ mmepụta ihe, ọgwụ, nri na ihe ịchọ mma, karịsịa n'ọhịa nke adhesives. Njikwa viscosity nke HPMC dị oke mkpa maka ịrụ ọrụ ngwaahịa. mkpa. Enwere ike imeziwanye viscosity nke HPMC na adhesives site n'ịgbanwe ihe anụ ahụ na nke kemịkal ya, yana ịkwalite nhazi na gburugburu ngwa ngwa.
1. Gbanwee molekụla arọ nke HPMC
The viscosity nke HPMC tumadi dabere na ya molekụla arọ. N'ikwu okwu n'ozuzu, ka ịdị arọ molekụla na-abawanye, ka viscosity dị elu. Site n'ịhọrọ HPMC nwere ibu molekụla kwesịrị ekwesị, viscosity nke nrapado nwere ike ịchịkwa nke ọma. N'ozuzu, HPMC nwere ibu molekụla dị elu ga-eme ka viscosity nke nrapado dịkwuo elu, mana ọ ga-emetụtakwa ọsọ na ịrụ ọrụ. Ya mere, nguzozi n'etiti viscosity na operability kwesịrị ịchọta na ngwa bara uru.
2. Jikwaa ogo nke nnọchi nke HPMC
HPMC bụ ngwaahịa enwetara site na methylcellulose site na mmeghachi omume hydroxypropylation akụkụ. Ogo nke nnọchi ya (ya bụ, ogo nnọchi nke hydroxypropyl na otu methyl) nwere mmetụta dị ukwuu na viscosity. Nrịgo dị elu nke nnọchi n'ozuzu na-ebelata viscosity nke HPMC, ebe ogo dị ala nke nnọchi na-abawanye viscosity. Ya mere, site n'ịgbanwe ogo nke nnọchi nke HPMC, enwere ike nweta njikwa viscosity dị irè. N'ọnọdụ ngwa dị iche iche, HPMC nwere ogo ngbanwe dị iche iche nwere ike ịdị mkpa iji mezuo ihe achọrọ nke nrapado.
3. Njikwa mgbasa okpomọkụ
Solubility na viscosity nke HPMC nwere njikọ chiri anya na okpomọkụ. N'ikwu okwu n'ozuzu, HPMC nwere viscosity dị elu mgbe agbazere na obere okpomọkụ. Site n'ịkwalite okpomọkụ mgbasa nke HPMC n'oge nkwadebe nrapado, enwere ike gbanwee viscosity nke ngwaahịa ikpeazụ. Dịka ọmụmaatụ, ịgbasa HPMC na okpomọkụ dị elu nwere ike ime ka viscosity mbụ dị ala, mana mmụba nke nta nke nta na viscosity ka okpomọkụ na-ebelata. Ya mere, site n'ịchịkwa okpomọkụ n'oge usoro ihe owuwu, enwere ike ime mgbanwe mgbanwe nke viscosity.
4. Tinye thickener
N'ime usoro nrapado HPMC, ịgbakwụnye oke nke thickener nwere ike ịbawanye viscosity nke ọma. Common thickeners na-agụnye xanthan chịngọm, carbomer, cellulose mmepụta, wdg Ndị a thickeners-arụ ọrụ synergistically na HPMC aka n'ozuzu viscosity nke nrapado. Na mgbakwunye, thickeners nwekwara ike melite nkwụsi ike na sag na-eguzogide nke nrapado, na-enye ya mma workability na ngwa.
5. Gbanwee mkpokọta ngwọta nke HPMC
Ịta nke HPMC ngwọta na mmiri nwere mmetụta kpọmkwem na viscosity. Ihe dị elu na ntinye uche, ka viscosity dị ukwuu. Na ngwa bara uru, viscosity nke nrapado nwere ike gbanwee n'ụzọ dị nro site n'ịchịkwa ihe ngwọta nke HPMC. Dịka ọmụmaatụ, mgbe ị na-akwadebe ihe nrapado, enwere ike ịbawanye viscosity site na iji nwayọọ nwayọọ na-abawanye ego nke HPMC, ma ọ bụ enwere ike ibelata viscosity site na ịgbanye.
6. Nkwalite nri nri
The viscosity nke HPMC nrapado bụghị nanị na-adabere na àgwà nke HPMC n'onwe ya, ma na-metụtara chiri anya dum usoro nhazi. Site n'ịkwalite ụdị na nha nke ihe ndị ọzọ dị na usoro ahụ, dị ka ndị na-ejuputa, ihe ndị na-edozi ihe, stabilizers, wdg, enwere ike imezi viscosity nke ọma. Dịka ọmụmaatụ, ịba ụba nke ndochi n'ụzọ kwesịrị ekwesị nwere ike ime ka viscosity dịkwuo elu, mana nnukwu ihe nkpuchi nwere ike ime ka nrapado nwee mmiri na-adịghị mma ma mee ka ọ sie ike itinye. Ya mere, nhazi usoro ezi uche dị na ya bụ isi ihe na-eme ka viscosity nke HPMC dịkwuo mma.
7. Ndozi nke pH uru
A na-emetụtakwa viscosity nke HPMC site na pH nke ngwọta. N'ime mpaghara ụfọdụ, viscosity nke HPMC na-agbanwe na uru pH. Na mkpokọta, HPMC na-egosiputa viscosity dị elu na nnọpụiche na gburugburu alkaline na-adịghị ike, ebe n'okpuru ọnọdụ acidic ma ọ bụ alkaline siri ike, viscosity nwere ike ibelata nke ukwuu. Ya mere, site n'ịgbanwe pH nke nrapado, njikwa nke viscosity nwere ike nweta. Dịka ọmụmaatụ, na ngwa ụfọdụ, pH nwere ike ime ka ọ kwụsie ike site n'ịgbakwunye ihe nkpuchi iji nọgide na-enwe viscosity kwụsiri ike.
8. Jiri ndị ọrụ na-ejikọta ọnụ
N'ọnọdụ ụfọdụ, mgbakwunye nke ndị na-emekọrịta ihe nwere ike ịbawanye viscosity nke HPMC nke ukwuu. Ndị ọrụ na-emekọrịta ihe nwere ike ịmepụta njikọ nke anụ ahụ ma ọ bụ kemịkalụ n'etiti ụmụ irighiri ihe HPMC ma kwalite mmekọrịta dị n'etiti ụdọ molekụla, si otú ahụ na-abawanye viscosity. Dịka ọmụmaatụ, n'ime ihe nkwụnye ihe owuwu, enwere ike ịmegharị njikọ nke HPMC site n'ịgbakwụnye boric acid kwesịrị ekwesị ma ọ bụ ion multivalent ndị ọzọ iji nweta usoro nrapado elu-viscosity.
9. Okpomọkụ na iru mmiri Control
Na ngwa bara uru, viscosity nke adhesives HPMC na-emetụtakwa ọnọdụ okpomọkụ na iru mmiri. Mmụba okpomọkụ n'ozuzu na-ebelata viscosity nke HPMC, ebe ịba ụba iru mmiri nwere ike ime ka viscosity fluctuation na nrapado. Ya mere, idowe ọnọdụ okpomọkụ na iru mmiri kwesịrị ekwesị n'ebe a na-ewu ụlọ nwere ike inye aka ịnọgide na-enwe ezigbo viscosity nke nrapado HPMC.
10. Nkwalite ọnọdụ nchekwa
Ọnọdụ nchekwa nke nrapado HPMC nwere mmetụta ogologo oge na viscosity. Iji nọgide na-enwe nkwụsi ike viscosity, adhesives kwesịrị ịchekwa na ebe akọrọ, dị jụụ, na-ezere nnukwu okpomọkụ na ọnọdụ iru mmiri dị elu. Na mgbakwunye, ogologo oge nchekwa nwere ike ibute mbelata nke viscosity. Ya mere, ịlele viscosity nke nrapado mgbe niile na ime mgbanwe dịka ọ dị mkpa bụkwa ihe dị mkpa iji hụ na mma nke nrapado.
Oge nzipu: Sep-03-2024