1. Ọdịdị molekụla
Ọdịdị molekụla nke sodium carboxymethyl cellulose (CMC) nwere mmetụta dị mkpa na solubility ya na mmiri. CMC bụ ihe sitere na cellulose, na njirimara nhazi ya bụ na ndị hydroxyl dị na cellulose na-eji otu carboxymethyl dochie anya akụkụ ma ọ bụ kpamkpam. Ogo nke nnọchi (DS) bụ isi ihe, nke na-egosi nkezi ọnụọgụ hydroxyl nke otu carboxymethyl nọchiri na nkeji glucose ọ bụla. Ọnụ ọgụgụ dị elu nke ngbanwe, ka hydrophilicity nke CMC na-esiwanye ike, na-abawanye ụba nke solubility. Otú ọ dị, oke ngbanwe nke oke nwere ike iduga na mmekọrịta dị n'etiti ụmụ irighiri ihe, nke n'aka nke ya na-ebelata solubility. Ya mere, ogo nke nnọchi dị nhata na solubility n'ime oke ụfọdụ.
2. Arọ molekụla
The molekụla arọ nke CMC na-emetụta ya solubility. N'ozuzu, ka ịdị arọ nke molekụla ahụ dị ntakịrị, otú ahụ ka ọ na-esiwanye ike. CMC dị elu nke molekụla nwere ogologo ogologo na mgbagwoju anya, nke na-eduga n'ịba ụba na mmekorita na ngwọta, na-egbochi ya solubility. CMC dị ala dị ala nwere ike ime mmekọrịta dị mma na ụmụ irighiri mmiri, si otú a na-emeziwanye ike.
3. Okpomọkụ
Okpomọkụ bụ ihe dị mkpa na-emetụta solubility nke CMC. N'ozuzu, mmụba nke okpomọkụ na-abawanye solubility nke CMC. Nke a bụ n'ihi na okpomọkụ dị elu na-abawanye ike nke mkpụrụ ndụ mmiri, si otú ahụ na-ebibi njikọ hydrogen na van der Waals n'etiti mkpụrụ ndụ CMC, na-eme ka ọ dịkwuo mfe igbari na mmiri. Otú ọ dị, oke okpomọkụ nwere ike ime ka CMC daa ma ọ bụ denature, nke na-adịghị akwado mgbasa.
4. pH uru
CMC solubility nwekwara nnukwu ndabere na pH nke ngwọta. N'ebe a na-anọpụ iche ma ọ bụ alkaline, otu carboxyl dị na mkpụrụ ndụ CMC ga-abanye n'ime COO⁻ ion, na-eme ka mkpụrụ ndụ CMC ebubo ebubo na-ezighị ezi, si otú ahụ na-eme ka mmekọrịta dị na mmiri mmiri na-eme ka ọ dịkwuo mma. Agbanyeghị, n'okpuru ọnọdụ acid siri ike, a na-egbochi ionization nke otu carboxyl na solubility nwere ike ibelata. Tụkwasị na nke ahụ, ọnọdụ pH dị oke egwu nwere ike ime ka mmebi nke CMC, si otú ahụ na-emetụta ike ya.
5. Ionic ike
Ike ionic na mmiri na-emetụta solubility nke CMC. Ngwọta nwere ike ionic dị elu nwere ike iduga mgbasawanye ọkụ eletrik n'etiti ụmụ irighiri CMC, na-ebelata ike ya. The salting pụta mmetụta bụ a ahụkarị onu, ebe elu ion mkpokọta belata solubility nke CMC na mmiri. Ike ionic dị ala na-enyere CMC aka igbari.
6. Mmiri siri ike
Isi ike mmiri, nke kachasị kpebisiri ike site na ntinye nke calcium na ion magnesium, na-emetụtakwa solubility nke CMC. Multivalent cations na mmiri siri ike (dị ka Ca²⁺ na Mg²⁺) nwere ike ịmepụta àkwà mmiri ionic na ndị otu carboxyl n'ime ụmụ irighiri CMC, na-ebute mkpokọta molecular na mbelata solubility. N'ụzọ dị iche, mmiri dị nro na-eme ka mgbasa nke CMC zuru ezu.
7. Mkpasu iwe
Ọgba aghara na-enyere CMC aka igbari na mmiri. Ọgba aghara na-abawanye mpaghara kọntaktị n'etiti mmiri na CMC, na-akwalite usoro mgbasa. Mgbagwoju anya zuru oke nwere ike igbochi CMC ịgbasa ma nyere ya aka ịgbasa na mmiri, si otú ahụ na-abawanye solubility.
8. Ọnọdụ nchekwa na njikwa
Ọnọdụ nchekwa na njikwa nke CMC na-emetụtakwa njirimara solubility ya. Ihe ndị dị ka iru mmiri, okpomọkụ, na oge nchekwa nwere ike imetụta ọnọdụ anụ ahụ na kemịkal nke CMC, si otú ahụ na-emetụta solubility ya. Iji nọgide na-enwe ezigbo solubility nke CMC, a ga-ezere ya site na ikpughe ogologo oge na okpomọkụ dị elu na iru mmiri dị elu, na nkwakọ ngwaahịa kwesịrị idobe nke ọma.
9. Mmetụta nke mgbakwunye
Ịgbakwunye ihe ndị ọzọ, dị ka ihe enyemaka mgbasa ma ọ bụ solubilizers, n'oge usoro mgbasa nke CMC nwere ike ịgbanwe ihe ndị na-edozi ahụ. Dịka ọmụmaatụ, ụfọdụ surfactants ma ọ bụ ihe ndị na-eme ka mmiri na-eme ka mmiri na-edozi ahụ nwere ike ịbawanye solubility nke CMC site n'ịgbanwe esemokwu elu nke ngwọta ma ọ bụ polarity nke ọkara. Na mgbakwunye, ụfọdụ ion ma ọ bụ kemịkalụ a kapịrị ọnụ nwere ike iji ụmụ irighiri ihe CMC na-emekọrịta ihe iji mepụta ogige ndị nwere ike soluble, si otú ahụ na-emeziwanye solubility.
Ihe ndị na-emetụta oke solubility nke sodium carboxymethyl cellulose (CMC) na mmiri na-agụnye usoro ihe omimi ya, ịdị arọ molecular, okpomọkụ, uru pH, ike ionic, ike mmiri, ọnọdụ mkpali, nchekwa na njikwa ọnọdụ, na mmetụta nke mgbakwunye. Ekwesịrị ịtụle ihe ndị a n'ụzọ zuru ezu na ngwa bara uru iji bulie solubility nke CMC wee zute ihe achọrọ ngwa ngwa. Ịghọta ihe ndị a dị mkpa maka iji na njikwa CMC ma na-enyere aka melite mmetụta ngwa ya na mpaghara dị iche iche.
Oge nzipu: Jul-10-2024