Hydroxypropyl methylcellulose (HPMC) bụ ngwakọta polymer na-agbaze mmiri nke a na-ejikarị na nkà mmụta ọgwụ, nri, ihe ụlọ na ubi ndị ọzọ. N'ihi na ọ dị mma ndim, ihe nkiri-akpụ, emulsifying, bonding na ndị ọzọ Njirimara, ọ na-ọtụtụ ebe-eji dị ka a thickener, stabilizer na suspending gị n'ụlọnga. Njirimara rheological nke HPMC, karịsịa arụmọrụ ya na okpomọkụ dị iche iche, bụ ihe dị mkpa na-emetụta mmetụta ngwa ya.
1. Nchịkọta nke Njirimara Rheological HPMC
Njirimara Rheological bụ ngosipụta zuru oke nke nrụrụ na njiri mara nke ihe n'okpuru ike mpụga. Maka ihe ndị dị na polymer, viscosity na shear thinning omume bụ ihe abụọ a na-ahụkarị rheological. The rheological Njirimara nke HPMC na-tumadi emetụta ihe ndị dị ka molekụla arọ, ịta, mgbaze Njirimara na okpomọkụ. Dị ka ether cellulose na-abụghị ionic, HPMC na-egosipụta pseudoplasticity na ngwọta mmiri, ya bụ, viscosity ya na-ebelata na ọnụ ọgụgụ shear na-abawanye.
2. Mmetụta nke okpomọkụ na HPMC viscosity
Okpomọkụ bụ otu n'ime isi ihe na-emetụta akụrụngwa rheological nke HPMC. Ka okpomọkụ na-abawanye, viscosity nke ngwọta HPMC na-ebelatakarị. Nke a bụ n'ihi na mmụba nke okpomọkụ na-ebelata njikọ njikọ hydrogen n'etiti ụmụ irighiri mmiri, si otú a na-ebelata ike mmekọrịta dị n'etiti ụdọ molekụla HPMC, na-eme ka ụdọ molekụla dị mfe ịkwanye ma na-asọba. Ya mere, na elu okpomọkụ, HPMC ngwọta na-egosipụta ala viscosity.
Agbanyeghị, mgbanwe viscosity nke HPMC abụghị njikọ ahịrị. Mgbe okpomọkụ na-ebili ruo n'ókè ụfọdụ, HPMC nwere ike ịnweta usoro mgbasa-mmiri mmiri. Maka HPMC, mmekọrịta dị n'etiti solubility na okpomọkụ dị mgbagwoju anya: n'ime ụfọdụ ọnọdụ okpomọkụ, HPMC ga-esi na ngwọta ya pụta, nke gosipụtara dị ka mmụba dị elu na viscosity ngwọta ma ọ bụ nhazi gel. Ihe omume a na-emekarị mgbe ọ na-abịaru nso ma ọ bụ gafere okpomọkụ mgbasa nke HPMC.
3. Mmetụta okpomọkụ na omume rheological nke ngwọta HPMC
Omume rheological nke ngwọta HPMC na-egosipụtakarị mmetụta dị nro, ya bụ, viscosity na-ebelata mgbe ọnụ ọgụgụ nke shea na-abawanye. Mgbanwe na okpomọkụ nwere mmetụta dị ukwuu na mmetụta a na-akpachapụ anya. N'ozuzu, ka okpomọkụ na-abawanye, viscosity nke ngwọta HPMC na-ebelata, mmetụta ya na-akpụ akpụ na-apụta ìhè karị. Nke a pụtara na na okpomọkụ dị elu, viscosity nke ngwọta HPMC na-adabere na ọnụ ọgụgụ nke shear, ya bụ, n'otu ọnụ ahịa shear, ngwọta HPMC na okpomọkụ dị elu na-agba ọsọ ngwa ngwa karịa na obere okpomọkụ.
Na mgbakwunye, mmụba nke okpomọkụ na-emetụtakwa thixotropy nke ngwọta HPMC. Thixotropy na-ezo aka na ihe onwunwe nke viscosity nke ihe ngwọta na-ebelata n'okpuru ọrụ nke ike shear, na viscosity ji nwayọọ nwayọọ na-agbake mgbe e wepụrụ ike ịkwa ahụ. N'ozuzu, mmụba nke okpomọkụ na-eduga n'ịbawanye na thixotropy nke ngwọta HPMC, ya bụ, mgbe ewepụsịrị ike ịkwa ahụ, viscosity na-agbake nwayọọ nwayọọ karịa n'okpuru ọnọdụ okpomọkụ dị ala.
4. Mmetụta nke okpomọkụ na omume gelation nke HPMC
HPMC nwere ihe pụrụ iche thermal gelation onwunwe, ya bụ, mgbe kpochara ruo ụfọdụ okpomọkụ (gel okpomọkụ), ihe ngwọta HPMC ga-agbanwe site na ọnọdụ ngwọta gaa na steeti gel. Usoro a na-emetụta nke ọma site na okpomọkụ. Ka okpomọkụ na-abawanye, mmekọrịta dị n'etiti hydroxypropyl na methyl substituents na HPMC molecules na-abawanye, na-ebute njikọ nke ụdọ molekụla, si otú ahụ na-akpụ gel. Ihe omume a dị oke mkpa na ụlọ ọrụ ọgwụ na nri nri n'ihi na enwere ike iji ya dozie nhazi na ntọhapụ nke ngwaahịa ahụ.
5. Ngwa na uru bara uru
Mmetụta nke okpomọkụ na rheological Njirimara nke HPMC dị oké mkpa na ngwa bara uru. N'ihi na ngwa nke HPMC ngwọta, dị ka ọgwụ nọgidere-nhapụ nkwadebe, nri thickeners, ma ọ bụ regulators maka ụlọ ihe, mmetụta nke okpomọkụ na rheological Njirimara ga-atụle iji hụ na nkwụsi ike na arụmọrụ nke ngwaahịa n'okpuru dị iche iche okpomọkụ ọnọdụ. Dịka ọmụmaatụ, mgbe ị na-akwadebe ọgwụ ndị na-ekpo ọkụ na-ekpo ọkụ, mmetụta nke mgbanwe okpomọkụ na viscosity na gelation omume nke matrix HPMC kwesịrị ka a tụlee iji bulie ọnụego ntọhapụ ọgwụ.
Okpomọkụ nwere mmetụta dị ukwuu na njirimara rheological nke hydroxypropyl methylcellulose. Okpomọkụ na-abawanye na-ebelata viscosity nke ngwọta HPMC, na-eme ka mmetụta ya na-akpachapụ anya na thixotropy, ma nwee ike ịkpata gelation thermal. Na ngwa bara uru, ịghọta na ịchịkwa mmetụta nke okpomọkụ na rheological Njirimara nke HPMC bụ isi ihe na-ebuli ngwaahịa arụmọrụ na usoro parameters.
Oge nzipu: Sep-05-2024