Hydroxyethyl Cellulose (HEC) na ndị ọzọ cellulose ethers (dị ka hydroxypropyl methylcellulose (HPMC), methylcellulose (MC), hydroxypropyl cellulose (HPC) na carboxymethyl cellulose (CMC)) bụ multifunctional polymers n'ọtụtụ ebe na ụlọ ọrụ, ewu, ọgwụ, nri na kwa ụbọchị. ụlọ ọrụ kemịkalụ. A na-emepụta ihe ndị a na-emepụta cellulose site n'ịgbanwe cellulose na-eme ka mmiri dị mma ma nwee ezigbo mmiri solubility, nkwụsi ike, nkwụsi ike na mmepụta ihe nkiri.
1. Hydroxyethyl cellulose (HEC)
1.1 Ọdịdị Chemical na Njirimara
A na-eme Hydroxyethyl Cellulose (HEC) site na hydroxyethylation nke cellulose na ethylene oxide n'okpuru ọnọdụ alkaline. Usoro nhazi nke HEC bụ njikọ ether nke e guzobere site na ngbanwe nke otu hydroxyl na cellulose molecule site na otu hydroxyethyl. Ihe owuwu a na-enye HEC ihe pụrụ iche:
Mmiri solubility: HEC bụ soluble na ma oyi na mmiri ọkụ na-etolite a transperent colloidal ngwọta.
Thickening: HEC nwere ọmarịcha ihe na-eme ka ọ dị mma ma na-ejikarị ya na ngwa chọrọ njikwa viscosity.
Nkwụsi ike: ngwọta HEC nwere nkwụsi ike dị elu na pH dị iche iche.
Biocompatibility: HEC abụghị ihe na-egbu egbu, na-adịghị ewe iwe, na enyi na enyi na ahụ mmadụ na gburugburu ebe obibi.
1.2 mpaghara ngwa
Ihe owuwu ụlọ: ejiri ya dị ka onye na-eji akwa na mmiri na-ejide mmiri maka ngwa ngwa ciment na ngwaahịa gypsum.
Mkpuchi na agba: eji eme ihe dị ka thickener, suspending agent and stabilizer.
Kemịkalụ kwa ụbọchị: a na-eji ya dị ka ihe na-esi ísì ụtọ na ihe ndị dị mkpa kwa ụbọchị dịka ncha na ncha ntutu.
Ogige ọgwụ: eji dị ka nrapado, thickener na suspending nnọchi maka mbadamba ọgwụ.
1.3 Uru na ọghọm
Uru: ezigbo mmiri solubility, nkwụsi ike kemịkalụ, mgbanwe pH sara mbara na enweghị nsị.
Ihe ọghọm: adịghị ike solubility na ụfọdụ ihe mgbaze, na ọnụahịa nwere ike ịdị elu karịa ụfọdụ cellulose ethers ndị ọzọ.
2. Ntụle nke cellulose ethers ndị ọzọ
2.1 Hydroxypropyl methylcellulose (HPMC)
2.1.1 Chemical Ọdịdị na Njirimara
A na-eme HPMC site na cellulose site na mmeghachi omume methylation na hydroxypropylation. Nhazi ya nwere ma methoxy (-OCH3) na hydroxypropoxy (-OCH2CH(OH)CH3).
Mmiri solubility: HPMC na-agbaze na mmiri oyi iji mepụta ngwọta colloidal transperent; ọ nwere adịghị ike solubility na mmiri ọkụ.
Ngwongwo na-akpụ akpụ: Ọ nwere ikike ịgbatị nke ọma.
Njirimara Gelling: Ọ na-etolite gel mgbe ọ dị ọkụ ma laghachi na ọnọdụ mbụ ya mgbe ọ dị jụụ.
2.1.2 Mpaghara ngwa
Ihe owuwu ụlọ: A na-eji ya dị ka ihe na-ekpuchi mmiri na mmiri maka ihe ndị dabeere na ciment na gypsum.
Nri: A na-eji ya dị ka emulsifier na stabilizer.
Ọgwụ: A na-eji ya dị ka ihe mgbakwunye maka capsules na mbadamba ọgwụ.
2.1.3 Uru na ọghọm
Uru: Ọmarịcha arụmọrụ na akụrụngwa gelling.
Ọdịmma: Ọ na-enwe mmetụta maka okpomọkụ ma nwee ike ịda na ngwa okpomọkụ dị elu.
2.2 Methyl cellulose (MC)
2.2.1 Chemical Ọdịdị na Njirimara
A na-enweta MC site na methylation nke cellulose ma nweekwa ihe ngbanwe methoxy (-OCH3).
Mmiri solubility: agbaze nke ọma na mmiri oyi iji mepụta ngwọta colloidal transperent.
Thickening: nwere mmetụta dị oke mkpa.
Gelation thermal: na-etolite gel mgbe a na-ekpo ọkụ na deels mgbe jụrụ oyi.
2.2.2 Mpaghara ngwa
Ihe owuwu ụlọ: ejiri ya dị ka ihe na-ekpuchi mmiri na mmiri maka ngwa agha na agba.
Nri: ejiri mee emulsifier na stabilizer.
2.2.3 Uru na adịghị ike
Uru: ike thickening ike, na-ejikarị na oyi na-atụ nhazi technology.
Ihe ọghọm: okpomọkụ na-enwe mmetụta, enweghị ike iji ya mee ihe na okpomọkụ dị elu.
2.3 Hydroxypropyl cellulose (HPC)
2.3.1 Chemical Ọdịdị na Njirimara
A na-enweta HPC site na hydroxypropyl cellulose. Nhazi ya nwere hydroxypropoxy (-OCH2CH(OH)CH3).
Mmiri solubility: agbaze na mmiri oyi na organic solvents.
Thicking: ezigbo arụmọrụ arụmọrụ.
Ihe na-emepụta ihe nkiri: na-emepụta ihe nkiri siri ike.
2.3.2 mpaghara ngwa
Ọgwụ: eji dị ka ihe mkpuchi na mbadamba ihe maka ọgwụ.
Nri: eji mee ihe dị ka thickener na stabilizer.
2.3.3 Uru na adịghị ike
Uru: multi-solvent solubility na magburu onwe film-akpụ ihe onwunwe.
Ihe ọghọm: ọnụ ahịa dị elu.
2.4 Carboxymethyl cellulose (CMC)
2.4.1 Chemical Ọdịdị na àgwà
A na-eme CMC site na imeghachi cellulose na chloroacetic acid, ma nwee otu carboxymethyl (-CH2COOH) na nhazi ya.
Mmiri solubility: soluble na mmiri oyi na mmiri ọkụ.
Ngwongwo na-agba agba: mmetụta dị oke mkpa.
Ionicity: bụ nke anionic cellulose ether.
2.4.2 mpaghara ngwa
Nri: eji mee ihe dị ka thickener na stabilizer.
Kemịkalụ kwa ụbọchị: a na-eji dị ka thickener maka ncha.
Ime akwụkwọ: ejiri ya dị ka mgbakwunye maka mkpuchi akwụkwọ.
2.4.3 Uru na ọghọm
Uru: ezi ndim na mbara ngwa ubi.
Ọdịmma: mmetụta nke electrolytes, ions na ngwọta nwere ike imetụta arụmọrụ.
3. Ntụnyere zuru oke
3.1 arụ ọrụ siri ike
HEC na HPMC nwere arụmọrụ na-eme ka ọ dị arọ ma ha abụọ nwere mmetụta dị mma. Otú ọ dị, HEC nwere mma mmiri solubility dị mma ma dị mma maka ngwa ndị chọrọ nghọta na obere mgbakasị ahụ. HPMC bara uru karịa na ngwa ndị chọrọ ikpo ọkụ na gel n'ihi njirimara thermogel ya.
3.2 Mmiri solubility
Enwere ike ịgbaze HEC na CMC na mmiri oyi na mmiri ọkụ, ebe HPMC na MC na-agbaze na mmiri oyi. HPC na-ahọrọ mgbe achọrọ ndakọrịta ọtụtụ ihe mgbaze.
3.3 Ọnụahịa na oke ngwa
A na-akwụkarị HEC ọnụ n'ụzọ kwesịrị ekwesị ma na-ejikarị ya eme ihe. Ọ bụ ezie na HPC nwere arụmọrụ dị mma, a na-ejikarị ya na ngwa achọrọ dị elu n'ihi ọnụ ahịa ya dị elu. CMC nwere ebe n'ọtụtụ ngwa dị ọnụ ala na ọnụ ala ya na arụmọrụ dị mma.
Hydroxyethyl cellulose (HEC) aghọwo otu n'ime cellulose ethers nke a na-ejikarị eme ihe n'ihi na ọ na-eme ka mmiri dị mma, nkwụsi ike na ike nke siri ike. E jiri ya tụnyere cellulose ethers ndị ọzọ, HEC nwere ụfọdụ uru na mmiri solubility na nkwụsi ike nke kemịkalụ, ma dabara maka ngwa ndị chọrọ ngwọta transperent na nnukwu pH mgbanwe. HPMC na-eme nke ọma na mpaghara ụfọdụ akọwapụtara n'ihi ihe na-eme ka ọ na-amị amị na nke na-ekpo ọkụ, ebe HPC na CMC na-arụ ọrụ dị mkpa na mpaghara ngwa ha n'ihi ihe ndị na-emepụta ihe nkiri na uru na-eri. Dị ka ụfọdụ ngwa chọrọ, ịhọrọ cellulose ether ziri ezi nwere ike ịkwalite arụmọrụ ngwaahịa na ọnụ ahịa.
Oge nzipu: Jul-10-2024