Uru nke Ọkwa Ọgwụ Ọgwụ HPMC

HPMC abụrụla otu n'ime ihe ndị a na-eji ọgwụ eme ihe n'ụlọ na mba ofesi, n'ihi na HPMC nwere uru ndị ọzọ na-enwetaghị.

1. Mmiri solubility

Soluble na mmiri oyi dị n'okpuru 40 Celsius ma ọ bụ 70% ethanol, nke a na-apụghị ịsacha na mmiri ọkụ n'elu 60 Celsius C, mana ọ nwere ike gel.

2. Chemical inertness

HPMC bụ ụdị na-abụghị ioniccellulose ether. Ngwọta ya enweghị ụgwọ ionic na anaghị emekọ ya na nnu ígwè ma ọ bụ ogige ionic organic. Ya mere, ndị ọzọ excipients adịghị emeghachi omume na ya n'oge usoro nkwadebe.

3. Nkwụsi ike

Ọ kwụsiri ike na acid na alkali, enwere ike ịchekwa ya ogologo oge n'etiti pH 3 na 11 na-enweghị mgbanwe doro anya na viscosity. The aqueous ngwọta nke HPMC nwere mgbochi mildew mmetụta na ike ịnọgide na-enwe ezi viscosity kwụsie ike n'oge ogologo oge nchekwa. Nkwụsi ike nke ọgwụ na-eji HPMC dị ka ihe eji eme nkwadebe dị mma karịa nke ọgwụ na-eji ihe ndị omenala (dị ka dextrin, starch, wdg).

4. viscosity na-agbanwe agbanwe

Enwere ike ịgwakọta viscosity dị iche iche nke HPMC dị ka oke dị iche iche si dị, na viscosity ya nwere ike ịgbanwe dịka iwu ụfọdụ siri dị, ma nwee mmekọrịta dị mma na linear, yabụ enwere ike họrọ oke dị ka achọrọ. 2.5 Metabolism inert HPMC adịghị etinye ya n'ahụ ma ọ bụ metabolized n'ime ahụ, ọ naghị enye okpomọkụ, ya mere ọ bụ ihe mgbakwunye nkwadebe ọgwụ dị mma. .

5. Nchekwa

A na-ewerekarị HPMC dị ka ihe na-adịghị egbu egbu na nke na-adịghị ewe iwe.