Hydroxypropyl Methylcellulose (HPMC) yog siv dav siv polymer nrog ntau hom kev siv hauv ntau yam lag luam, suav nrog tshuaj, khoom noj, kev tsim kho, thiab tshuaj pleev ib ce. Qhov ntau yam sib xyaw no muaj cov khoom tshwj xeeb uas ua rau nws muaj txiaj ntsig hauv kev sib txawv thiab cov txheej txheem.
1. Cov qauv thiab cov khoom
1.1 Molecular Structure: HPMC yog ib qho semisynthetic polymer muab los ntawm cellulose, uas yog biopolymer ntau tshaj plaws hauv ntiaj teb. Nws yog tsim los ntawm kev hloov kho tshuaj ntawm cellulose, tshwj xeeb los ntawm kev kho nws nrog propylene oxide thiab methyl chloride los qhia hydroxypropyl thiab methyl pawg, feem.
1.2 Cov Khoom Siv Lub Cev: HPMC feem ntau pom muaj cov hmoov dawb lossis dawb dawb. Nws tsis muaj ntxhiab, tsis qab, thiab tsis muaj tshuaj lom, ua rau nws muaj kev nyab xeeb rau kev siv ntau yam kev siv. Lub solubility ntawm HPMC nyob ntawm cov yam ntxwv xws li qhov hnyav molecular, qib ntawm kev hloov pauv, thiab kub. Nws nthuav tawm cov yeeb yaj kiab zoo heev thiab tuaj yeem tsim cov yeeb yaj kiab pob tshab thaum yaj hauv dej.
1.3 Rheological Properties: HPMC cov kev daws teeb meem nthuav tawm tus cwj pwm pseudoplastic, txhais tau tias lawv cov viscosity txo qis nrog nce shear npaum li cas. Cov cuab yeej no muaj txiaj ntsig zoo hauv kev siv xws li txheej txheej, qhov yooj yim thov thiab qib siab xav tau.
2. Synthesis
Lub synthesis ntawm HPMC muaj ob peb kauj ruam. Ua ntej, cellulose feem ntau yog tau los ntawm cov ntoo pulp lossis paj rwb linters. Tom qab ntawd, nws nkag mus rau etherification cov tshuaj tiv thaiv nrog propylene oxide thiab methyl chloride nyob rau hauv kev tswj xyuas kom qhia hydroxypropyl thiab methyl pawg mus rau hauv cov pob txha cellulose. Qhov degree ntawm kev hloov pauv (DS) ntawm cov pab pawg no tuaj yeem hloov kho kom haum rau cov khoom ntawm HPMC polymer rau cov ntawv thov tshwj xeeb.
3. Daim ntawv thov
3.1 Pharmaceuticals: HPMC yog dav siv nyob rau hauv cov tshuaj formulations vim nws biocompatibility, mucoadhesive zog, thiab tswj kev tso tawm muaj peev xwm. Nws yog feem ntau ua hauj lwm raws li ib tug binder, zaj duab xis qub, disintegrant, thiab sustained-tso tus neeg sawv cev nyob rau hauv cov ntsiav tshuaj formulations. Tsis tas li ntawd, HPMC-raws li gel formulations yog siv nyob rau hauv ophthalmic npaj kom ntev lub sij hawm nyob rau hauv tshuaj nyob rau ntawm lub qhov muag.
3.2 Kev Lag Luam Khoom Noj: Hauv kev lag luam khoom noj khoom haus, HPMC yog siv los ua cov thickener, stabilizer, emulsifier, thiab tus neeg saib xyuas cov dej noo. Nws feem ntau pom muaj nyob rau hauv cov khoom noj siv mis, khoom ci, kua ntses, thiab dej haus. HPMC pab txhim kho qhov kev ntxhib los mos, ruaj khov, thiab lub qhov ncauj ntawm cov khoom noj khoom haus tsis hloov pauv lawv saj lossis khoom noj muaj txiaj ntsig.
3.3 Cov Khoom Siv Siv: HPMC yog cov khoom tseem ceeb hauv kev tsim kho cov ntaub ntawv xws li cement-based mortars, renders, thiab vuas adhesives. Nws ua haujlwm raws li tus neeg saib xyuas dej, txhim kho kev ua haujlwm, txo qis qis, thiab txhim kho cov adhesion ntawm cov ntaub ntawv no rau substrates. HPMC-raws li mortars nthuav tawm txhim kho kev tiv thaiv kev tawg thiab shrinkage, ua rau cov qauv ruaj khov thiab zoo nkauj.
3.4 Tshuaj pleev ib ce: Hauv kev lag luam tshuaj pleev ib ce, HPMC tau siv ntau hom tshuaj, suav nrog tshuaj pleev, tshuaj pleev, gels, thiab mascaras. Nws ua hauj lwm raws li ib tug thickener, emulsifier, stabilizer, thiab zaj duab xis qub nyob rau hauv cov khoom no. HPMC muab cov khoom tsim nyog rheological, txhim kho kev ntxhib los mos, thiab muab cov teebmeem ntev ntev hauv cov tshuaj pleev ib ce.
4. Cov kev cia siab yav tom ntej
Qhov kev thov rau HPMC xav tias yuav loj hlob ntxiv nyob rau xyoo tom ntej, tau tsav los ntawm kev nthuav dav hauv kev siv tshuaj, khoom noj, kev tsim kho, thiab tshuaj pleev ib ce. Kev tshawb fawb tsis tu ncua yog tsom rau kev tsim cov qauv tshiab thiab txhim kho kev ua haujlwm ntawm cov khoom uas twb muaj lawm. Kev nce qib hauv nanotechnology tuaj yeem ua rau kev txhim kho HPMC-raws li nanocomposites nrog kev txhim kho cov tshuab, thermal, thiab cov khoom thaiv kev tiv thaiv, qhib cov hauv kev tshiab hauv ntau qhov kev lag luam.
Hydroxypropyl Methylcellulose (HPMC) yog ntau yam polymer nrog ntau yam kev siv thoob plaws kev lag luam sib txawv. Nws qhov tshwj xeeb ua ke ntawm cov khoom, suav nrog biocompatibility, rheological tswj, thiab kev muaj peev xwm ua yeeb yaj kiab, ua rau nws tseem ceeb hauv kev tshuaj, khoom noj, kev tsim kho, thiab tshuaj pleev ib ce. Nrog rau kev tshawb fawb thiab kev loj hlob tsis tu ncua, HPMC tau npaj los ua cov khoom tseem ceeb hauv ntau hom kev tsim thiab cov ntaub ntawv nyob rau yav tom ntej.
Post lub sij hawm: Apr-15-2024