Hydroxypropyl Methylcellulose (HPMC) yog cov khoom siv ntau yam siv dav hauv ntau lub lag luam vim nws cov khoom siv tshuaj lom neeg tshwj xeeb. Qhov no polymer yog muab los ntawm cellulose, ib tug natural polymer pom nyob rau hauv lub cell phab ntsa ntawm cov nroj tsuag, los ntawm ib tug series ntawm tshuaj hloov kho. HPMC nthuav tawm ntau yam tshuaj lom neeg, ua rau nws tsim nyog rau kev siv tshuaj, kev tsim kho, khoom noj khoom haus, tshuaj pleev ib ce, thiab ntau lwm yam.
Hydrophilic Nature: Ib qho ntawm cov khoom siv tshuaj tseem ceeb ntawm HPMC yog nws qhov xwm txheej hydrophilic. Lub xub ntiag ntawm hydroxyl (-OH) pawg hauv cov pob txha cellulose ua rau HPMC muaj dej-soluble heev. Cov cuab yeej no tso cai rau nws yaj hauv dej los tsim cov kua nplaum colloidal, uas pom cov ntawv thov hauv ntau yam lag luam xws li tshuaj thiab khoom noj.
Viscosity: HPMC nthuav tawm ntau yam viscosity nyob ntawm seb yam xws li qhov hnyav ntawm molecular, qib ntawm kev hloov pauv, thiab cov concentration hauv cov tshuaj. Nws tuaj yeem tsim kho kom tau raws li cov kev xav tau tshwj xeeb hauv viscosity hauv ntau daim ntawv thov, suav nrog ua cov thickener, stabilizer, lossis cov neeg ua yeeb yaj kiab.
Kev Tsim Yeeb Yam: HPMC muaj peev xwm tsim cov yeeb yaj kiab pob tshab thiab hloov tau yooj yim thaum yaj hauv dej. Cov cuab yeej no yog siv nyob rau hauv kev lag luam kws tshuaj rau txheej ntsiav tshuaj thiab hauv kev lag luam khoom noj khoom haus rau cov yeeb yaj kiab noj tau ntawm cov khoom noj khoom haus.
Thermal Gelation: Qee qib ntawm HPMC nthuav tawm qhov tshwm sim hu ua "thermal gelation" lossis "thermal gel point." Cov cuab yeej no ua rau tsim cov gels ntawm qhov kub siab, uas rov qab mus rau lub xeev sol thaum txias. Thermal gelation yog siv rau hauv daim ntawv thov xws li kev tswj cov tshuaj tso tawm thiab ua cov thickening tus neeg sawv cev hauv cov khoom noj.
pH Stability: HPMC ruaj khov nyob rau ntau yam ntawm pH qhov tseem ceeb, los ntawm acidic mus rau alkaline tej yam kev mob. Cov cuab yeej no ua rau nws tsim nyog rau kev siv hauv cov qauv uas pH stability yog qhov tseem ceeb, xws li hauv cov chaw muag tshuaj, qhov twg nws tuaj yeem siv los hloov kho cov tshuaj tso tawm.
Chemical Inertness: HPMC yog tshuaj inert, txhais tau tias nws tsis hnov mob nrog cov tshuaj feem ntau nyob rau hauv ib txwm muaj mob. Cov cuab yeej no pab txhawb rau nws txoj kev ruaj ntseg thiab kev sib raug zoo nrog ntau yam ntawm lwm cov khoom xyaw hauv cov qauv.
Kev sib raug zoo nrog Lwm Cov Polymers: HPMC nthuav tawm zoo sib xws nrog lwm cov polymers thiab cov khoom siv ntxiv uas feem ntau siv hauv cov qauv. Qhov kev sib raug zoo no tso cai rau kev tsim cov kev sib xyaw ua ke nrog cov khoom zoo dua qub rau cov ntawv thov tshwj xeeb.
Tsis yog-ionic Xwm: HPMC yog cov tsis-ionic polymer, txhais tau tias nws tsis nqa hluav taws xob hauv kev daws teeb meem. Cov cuab yeej no ua rau nws tsis tshua muaj kev hloov pauv hauv ionic zog thiab pH piv rau cov khoom siv hluav taws xob, ua kom nws ruaj khov hauv cov qauv sib txawv.
Biodegradability: Txawm hais tias muab los ntawm cellulose, ib qho kev siv txuas ntxiv mus, HPMC nws tus kheej tsis yog biodegradable. Txawm li cas los xij, nws raug suav tias yog biocompatible thiab ib puag ncig tus phooj ywg piv rau qee cov hluavtaws polymers. Kev siv zog txuas ntxiv mus tsim biodegradable derivatives ntawm cellulose ethers zoo li HPMC rau kev siv tau zoo dua.
Solubility nyob rau hauv Organic Solvents: Thaum muaj soluble hauv dej, HPMC nthuav tawm cov solubility tsawg hauv cov kuab tshuaj organic. Cov cuab yeej no tuaj yeem ua tau zoo nyob rau hauv qee yam kev siv, xws li hauv kev npaj cov qauv tso tawm uas muaj cov kuab tshuaj organic siv los tswj cov tshuaj tso tawm.
Hydroxypropyl Methylcellulose (HPMC) muaj ntau hom tshuaj lom neeg uas ua rau nws muaj txiaj ntsig zoo hauv ntau qhov kev lag luam. Nws qhov hydrophilic xwm, viscosity tswj, zaj duab xis-tsim muaj peev xwm, thermal gelation, pH stability, tshuaj inertness, compatibility nrog rau lwm yam polymers, non-ionic xwm, thiab solubility yam ntxwv pab rau nws dav siv nyob rau hauv pharmaceuticals, kev tsim kho, khoom noj khoom haus, tshuaj pleev ib ce, thiab lwm yam. teb.
Post lub sij hawm: May-08-2024