Kev faib tawm los ntawm txoj kev tswj hwm
1. Cov ntsiav tshuaj (cov ntsiav tshuaj coated, matrix ntsiav tshuaj, ntsiav tshuaj ntau txheej), ntsiav tshuaj, ntsiav tshuaj (enteric-coated capsules, tshuaj ntsiav tshuaj ntsiav tshuaj, coated capsules) thiab lwm yam. muab los ntawm txoj hnyuv.
2. Parenteral tswj kev txhaj tshuaj, suppositories, films, implants, thiab lwm yam.
Raws li cov txheej txheem kev npaj sib txawv, cov kev npaj tso tawm tuaj yeem muab faib ua:
1. Skeleton-dispersed sustained-release npaj ①Water-soluble matrix, carboxymethylcellulose (CMC), hydroxypropylmethylcellulose (HPMC), polyvinylpyrrolidone (PVP), thiab lwm yam. yog feem ntau siv los ua cov ntaub ntawv matrix; ②Fat-soluble matrix, Cov roj thiab cov khoom siv quav ciab feem ntau yog siv los ua cov khoom siv pob txha; ③ Cov pob txha insoluble, insoluble non-toxic plastics feem ntau yog siv los ua cov khoom siv pob txha.
2. Membrane-controlled sustained-release npaj feem ntau muaj xws li film-coated sustained-release npaj thiab sustained-tso microcapsules. Lub hom phiaj ntawm kev tswj cov tshuaj tso tawm feem ntau ua tiav los ntawm kev tswj cov tuab ntawm cov tshuaj ntsiav, txoj kab uas hla ntawm micropores, thiab curvature ntawm micropores.
3. Sustained-tso emulsions Cov dej-soluble tshuaj tuaj yeem ua rau hauv W / O emulsions, vim tias cov roj muaj qee yam cuam tshuam rau qhov diffusion ntawm cov tshuaj molecules kom ua tiav lub hom phiaj ntawm kev tso tawm.
4. Sustained-tso tawm kev npaj rau kev txhaj tshuaj yog ua los ntawm cov roj tov thiab kev txhaj tshuaj ncua kev kawm.
5. Sustained-tso zaj duab xis npaj yog sustained-tso zaj duab xis npaj ua los ntawm encapsulating tshuaj nyob rau hauv polymer zaj duab xis compartments, los yog dissolving thiab dispersing lawv nyob rau hauv cov ntaub ntawv polymer.
Post lub sij hawm: Apr-17-2023