HPMC (HydroxyPropyyl methylulose) yog ib feem uas siv cov tshuaj uas siv tau siv hauv cov ntaub ntawv tshuaj, suav cov ntsiav tshuaj, ntsiav tshuaj, thiab cov tshuaj ophthalmic, thiab cov tshuaj ophthalmic. Ib qho ntawm cov khoom tseem ceeb ntawm HPMC yog nws viscosity, uas cuam tshuam rau cov khoom ntawm cov khoom kawg. Kab lus no yuav tshawb txog kev sib raug zoo ntawm HPMC viscosity thiab qhov kub thiab txias thiab ua tib zoo hais thaum siv qhov kev zam no.
Kev sib raug zoo ntawm HPMC viscosity thiab kub
HPMC yog hydrophilic polymer uas yog soluble hauv dej thiab lwm cov kuab tshuaj polar. Thaum HPMC yog yaj hauv dej, nws tsim cov kev daws teeb meem vim yog cov polymer lub siab molecular hnyav thiab qib siab ntawm hydrophilicity. Lub viscos ntawm HPMC cov kev daws teeb meem cuam tshuam los ntawm ntau yam, suav nrog kev sib haum xeeb ntawm cov tshuaj, qhov ntsuas kub, thiab cov qauv ntawm cov kuab tshuaj.
Ib qho ntawm cov ntsiab lus tseem ceeb cuam tshuam rau cov viscosity ntawm HPMC tov yog qhov kub. Lub viscosity ntawm HPMC cov kev daws teeb meem tsawg dua nrog kev nce qib. Qhov no yog vim tias thaum muaj qhov kub siab dua, cov ntaub pua av polymer ua kua ntau dua, ua rau muaj cov sib xyaw ua ke uas tuav cov saw polymer ua ke. Raws li qhov tshwm sim, lub viscosity ntawm kev daws teeb meem tsawg thiab cov kua dej ntawm cov tshuaj muaj nce.
Kev sib raug zoo ntawm qhov kub thiab kub thiab HPMC viscosity tuaj yeem piav qhia los ntawm cov ntawv sib npaug ntawm Arraenius. Cov txheej txheem Arrhenius yog ib qho kev sib npaug ntawm kev ua lej uas piav qhia txog kev sib raug zoo ntawm tus nqi ntawm kev siv tshuaj lom neeg thiab qhov kub ntawm lub system. Rau HPMC cov kev daws teeb meem, kev sib npaug ntawm Arrhenius tuaj yeem siv los piav qhia txog kev sib raug zoo ntawm kev daws viscosity thiab qhov system txias.
Cov txheej txheem ARHENIUS yog muab los ntawm:
k = ae ^ (- EA / RT)
Qhov twg K yog tus nqi tas li, A yog qhov ua ntej tshaj tawm, EA yog lub zog ua kom muaj zog, R yog cov roj tas li, thiab t yog qhov ntsuas kub. Lub visccosity ntawm HPMC cov kev daws teeb meem yog cuam tshuam nrog tus nqi ntws ntawm cov kuab tshuaj los ntawm cov txheej txheem qub, uas yog tswj hwm los ntawm tib tus nqi ntawm kev siv tshuaj lom neeg. Yog li, cov kab zauv Arrhenius tuaj yeem siv los piav qhia txog kev sib raug zoo ntawm kev daws viscosity thiab qhov system txias.
Yam kom nco ntsoov thaum siv hpmc
Thaum ua haujlwm nrog HPMC, ntau phau ceev faj yuav tsum tau coj los xyuas kom muaj kev nyab xeeb thiab kev sib tw ntawm cov polymer. Cov kev ceev faj no suav nrog:
1. Siv cov khoom tiv thaiv tiv thaiv
Nws yog ib qho tseem ceeb uas yuav tau siv cov khoom siv tiv thaiv xws li hnab looj tes, goggles, thiab lub tsho ntev thaum tuav HPMC. Qhov no yog vim HPMC tuaj yeem ua rau tawv nqaij thiab qhov muag, thiab tuaj yeem ua pa nyuaj yog nqus tau. Yog li ntawd, nws yog ib qho tseem ceeb uas yuav tau ua kauj ruam txo qis kev pheej hmoo ntawm kev phom sij.
2. Txuag HPMC raug
HPMC yuav tsum tau muab cia rau hauv qhov chaw txias, qhuav kom tiv thaiv nqus cov dej noo hauv huab cua. Qhov no yog vim HPMC yog hygroscopic, lub ntsiab lus nws nqus dej noo los ntawm nws ib puag ncig ib puag ncig. Yog HPMC nqus tau ntau dhau noo, nws tuaj yeem cuam tshuam rau viscosity thiab cov khoom ntawm cov khoom kawg.
3. Ua tib zoo saib kom pom thiab kub
Thaum tsim nrog HPMC, nco ntsoov ua tib zoo mloog rau kev pom zoo thiab ntsuas kub ntawm kev daws teeb meem. Qhov no vim tias lub viscosity ntawm HPMC cov kev daws teeb meem yog txiav txim siab ntau ntawm cov no. Yog hais tias lub siab lossis kub dhau lawm lossis qis dhau, nws yuav cuam tshuam rau viscosity thiab cov khoom ntawm cov khoom kawg.
4. Siv cov txheej txheem tsim nyog
Thaum ua HPMC, nws yog ib qho tseem ceeb kom siv cov qauv tsim nyog los ua kom muaj kev nyab xeeb thiab muaj txiaj ntsig zoo ntawm cov polymer. Qhov no yuav suav nrog kev siv cov hau kev tsawg-shear
5. Kuaj Xyuas
Thaum siv HPMC raws li kev zam tshwj xeeb, nws yog ib qho tseem ceeb kom kuaj tau li cas nrog lwm cov khoom siv kom zoo siab thiab cov khoom xyaw nquag hauv kev tsim qauv. Qhov no yog vim HPMC tuaj yeem cuam tshuam nrog lwm cov khoom xyaw rau hauv kev tsim, cuam tshuam rau kev ua tau zoo thiab kev ruaj ntseg ntawm cov khoom kawg. Yog li ntawd, nws yog ib qho tseem ceeb kom ua tau cov kev paub txog kev txheeb xyuas cov teeb meem muaj peev xwm ua ntej ua tiav nrog kev tsim qauv.
Hauv kev xaus
Lub viscos ntawm HPMC cov kev daws teeb meem cuam tshuam los ntawm ntau yam, suav nrog kev xav, kub, thiab Ph. Lub tshuaj viscosity ntawm HPMC cov kev daws teeb meem tsawg dua nrog kev nce qib vim muaj kev muaj peev xwm nce ntxiv ntawm cov saw polymer. Thaum ua haujlwm nrog HPMC, nws yog ib qho tseem ceeb uas yuav tau txais kev ceev faj tsim nyog kom ntseeg tau tias muaj kev nyab xeeb thiab ua tau zoo ntawm cov polymer. Cov kev ceev faj no suav nrog siv cov cuab yeej tiv thaiv, kom pom kev zoo HPMC, siv cov txheej txheem uas tsim nyog, thiab kuaj cov khoom siv kom tsim nyog, thiab ntsuas kev sib xyaw nrog lwm cov khoom xyaw hauv cov mis. Los ntawm kev coj cov kev ceev faj cov kev ceev faj, HPMC tuaj yeem siv los ua qhov zoo siv hauv ntau yam tshuaj noj tshuaj.
Sijhawm Sijhawm: Sep-25-2023