Qhov sib txawv ntawm HPMC thiab MC

HydroxyPropyyl Methylcellulose (HPMC)thiabMethylcellulose (MC)Yog ob qho tib si cellulose derivative feem ntau yog siv nyob rau hauv ntau yam kev lag luam, suav nrog cov tshuaj, zaub mov, tshuaj pleev ib ce, thiab kev tsim kho. Txawm hais tias lawv zoo sib xws, cov khoom no muaj cov tshuaj thiab cov ntawv thov sib txawv.

1. Cov Qauv Tshuaj

Ob qho tib si HPMC thiab MC yog cov kab mob cellulose, tab sis cov qhov sib txawv tseem ceeb nyob hauv cov pab pawg ua ke nrog cov pob cellulose.

Methylcellulose (MC): Qhov no yog tsim los ntawm methylation ntawm cellulose. Hauv cov txheej txheem no, methyl pawg (-ch3) tau txuas rau cov pawg hydroxyl ntawm cov xov xwm cellulose. Lub methylation degree feem ntau sib txawv ntawm 20-30%, nyob ntawm qib ntawm MC, uas cuam tshuam rau nws solubility thiab lwm yam khoom.

HydroxyPropyyl Methylcellulose (HPMC): Kimacell® Tus Neeg Muaj Zog Ntau Ntxiv. Ntxiv nrog methylation, nws kuj undergoes hydroxyproper. Hydroxypropyl pawg (-ch2chohch3) tau qhia rau lub cellulose molecule, nrog rau pawg methyl. Lub hydroxyprropy thiab methylation degree ntawm HPMC tuaj yeem sib txawv, uas muab rau ntau cov qhab nia HPMC nrog cov yam ntxwv sib txawv.

2. So

Solubility yog ib qho tseem ceeb tshaj plaws thaum sib piv MC thiab HPMC. Cov solubility ntawm ob qho tib si ntawm cov cellulose derivatives yog nyob ntawm cov qib hloov pauv thiab cov qauv tshwj xeeb ntawm cov khoom siv.

Methylcellulose (MC): Mc yog soluble hauv dej kub tab sis ua ib qho gel thaum txias txias. Qhov no tshwj xeeb cov cuab yeej ntawm kev tsim cov gels thaum ua kom sov thiab rov qab mus rau lub xeev ua kua thaum txias tshaj plaws yog ib qho tseem ceeb tshaj plaws ntawm MC. Nws yog insoluble hauv dej txias, tab sis soluble hauv dej kub saum toj ib qho ntsuas kub (50-70 ° C), thiab cov txheej txheem gelation yog reversible.

HydroxyPropyyl Methylcellulose (HPMC): HPMC, ntawm qhov tod tes, yog soluble hauv ob qho tib si txias thiab dej kub. Qhov no ua rau nws ntau yam ntxiv piv rau MC. Solubility ntawm HPMC yog pawg los ntawm hom kev hloov pauv (piv txwv li methyl ntawm methyl rau hydroxyproproreL pab pawg. Hloov dua cov qib tsawg dua yuav ua rau HPMC ntau soluble hauv dej ntawm qis dua kub.

3. Viscosity

Viscosity plays lub luag haujlwm tseem ceeb hauv ntau daim ntawv thov, tshwj xeeb hauv cov chaw tshuaj thiab kev lag luam khoom noj khoom haus.

Methylcellulose (MC): Lub viscosity ntawm Kimacell®MC cov kev daws teeb meem yog qhov kub-nyob. Lub viscosity nce thaum rhuab, thiab nws ua pov thawj qhov tshwm sim ntawm gelation. Cov degree ntawm kev hloov pauv kuj cuam tshuam rau cov viscosity, nrog ntau dua cov qib hloov chaw feem ntau ua rau visccosity ntau dua.

HydroxyPropyyl Methylcellulose (HPMC): HPMC feem ntau muaj cov viscosity ntau dua piv rau MC. Lub visccosity ntawm HPMC kuj tau cuam tshuam los ntawm cov qib kev hloov pauv, tab sis nws tseem ruaj ntseg thoob plaws ib qho kub. Tsis tas li ntawd, HPMC tuaj yeem ua kom haum kom muaj cov viscosities ntau, los ntawm qis rau siab, nyob ntawm cov ntawv thov.

4. Cov Ntawv Thov

Ob qho tib si MC thiab HPMC tau siv ntau yam hauv cov tshuaj, thiab cov khoom siv tshuaj pleev ib ce, tab sis cov khoom tshwj xeeb ntawm txhua qhov ua rau lawv tsim nyog rau qee cov ntawv thov.

Methylcellulose (MC):

Kws Tshuaj: MC feem ntau siv los ua cov phau ntawv, ua tsis taus, thiab txheej txheem tus neeg sawv cev hauv cov ntsiav tshuaj ntawm cov ntsiav tshuaj ua haujlwm vim nws cov khoom gelation. Nws tseem siv nyob rau hauv kev tswj-tso tawm cov yeeb yaj kiab.

Kev Lag Luam Khoom Noj: MC yog siv los ua cov zaub mov ua kom sov, emulsifier, thiab stabilizer. Nws cov khoom siv roj teeb uas muaj txiaj ntsig zoo hauv kev ua cov khoom lag luam xws li cov mis nyuj khov, cov khoom noj nyias nyias, thiab cov khoom bakery.

Tshuaj pleev ib ce: MC siv rau hauv cov tshuaj pleev ib ce rau nws cov thickening, thiab steeilizing cov khoom hauv cov khoom lag luam zoo li tshuaj pleev, tshuaj zawv plaub hau, thiab cream.

HydroxyPropyyl Methylcellulose (HPMC):

Kws Tshuaj: HPMC tau siv dav ua ib phau ntawv tuav thiab tswj hwm-tso tus neeg sawv cev hauv cov ntsiav tshuaj. Nws tseem siv nyob rau hauv cov kev daws teeb meem ophthalmic ua cov roj nplua nyeem thiab hauv cov tshuaj gel-raws cov tshuab tshuaj.

Kev Lag Luam Khoom Noj: HPMC yog siv nyob rau hauv gluten-dawb ci, raws li nws mimics cov kev ntxhib los mos thiab elasticity ntawm gluten hauv mov paj. Nws tseem siv los ua cov stabilizer thiab emulsifier hauv ntau cov zaub mov tiav.

Kev tsa tsev: HPMC yog siv los ua kev ntxiv nyob rau hauv xis mas, plaster, thiab pobzeb cov nplaum. Nws txhim kho cov haujlwm ua haujlwm, tso dej ua kom rov qab, thiab cov nplaum.

5. Lwm cov khoom

Hygroscopicity: HPMC feem ntau ntau hygroscopic (dej-nyiam) tshaj mc, uas ua rau nws muaj txiaj ntsig hauv cov ntawv thov uas yuav tsum muaj kev tuav noo noo.

Thermal ruaj khov: Mc nyhav rau cov khoom pov thawj zoo dua thermal stability vim nws cov khoom gelation. HPMC, thaum ruaj khov nyob rau hauv ib dav dav dav ntau, tej zaum yuav tsis muab tib lub thermal gelation nyhuv ua mc.

6. Ntsiab lus ntawm qhov sib txawv

Thaum ob qho tib siHPMCthiabMCyog cov cellulose derivatives nrog cov ntawv thov sib tshooj, lawv cov qauv siv tshuaj sib txawv thiab cov khoom ua rau lawv haum ntau rau kev siv sib txawv. MC tshwj xeeb muaj txiaj ntsig zoo hauv cov ntawv thov tau txais txiaj ntsig los ntawm nws cov cuab yeej gelation, thaum HPMC cov khoom ruaj khov ua rau nws ntau ntxiv rau kev lag luam, suav nrog kev ua zaub mov noj thiab cov khoom noj. Nkag siab cov kev sib txawv no pab nyob rau hauv kev xaiv cov khoom kom tsim nyog rau cov ntawv thov tshwj xeeb.