Txheej Txheem Flow of HydroxyPropyyl Metylcellulose

HydroxyPropyyl methylcellulose (HPMC)yog ib feem siv dej-soluble cellulose cellulose cellulose derivative, siv dav siv hauv kev tsim kho, cov xim pleev xim, cov tshuaj, khoom noj thiab tshuaj pleev ib ce. Nws cov txheej txheem ntau lawm yog qhov sib txawv thiab cuam tshuam nrog ntau cov kauj ruam, feem ntau yog suav nrog kev sib cais, cov tshuaj tiv thaiv, ntxuav, kom qhuav thiab ua kom qhuav thiab txhaws cov cellulose.

1. Cov Khoom Siv Khoom Raw

Kev tsim cov hydroxypropyl methylcellulose siv cov nroj tsuag xws li ntoo lossis paj rwb ua cov khoom raw. Ua ntej, cellulose xav tau muab rho tawm los ntawm cov nroj tsuag. Cov muab rho tawm ntawm cellulose feem ntau yog degreeh li, tshuaj dawb, thiab impriffe, thiab impurity tshem kom tau txais cov ntaub ntawv ntshiab cellulose.

2. Kev tshem tawm ntawm cellulose

Cellulose muaj cov tub rog tsis zoo hauv dej, yog li nws yuav tsum tau yaj los ntawm cov kuab tshuaj thaum lub sijhawm ua haujlwm. Cov kuab tshuaj uas muaj sib xyaw ntawm ammonium chloride thiab dej, lossis sib xyaw ntawm ammonia thiab ethanol. Ua ntej, cov cellulose ntshiab yog tov nrog cov kuab tshuaj thiab kho thaum muaj kub kom ntseeg tau tias lub cellulose tuaj yeem yaj tag.

3. Methylation Rhais

Tus neeg sawv cev methylating (xws li methyl chloride lossis methyl chloride) yog ntxiv rau cov tshuaj tiv thaiv kab mob rau methylation. Lub hom phiaj tseem ceeb ntawm cov tshuaj no yog los qhia cov tshuaj methyl (-ochiv) los ua cov methyl cellulose. Cov txheej txheem no feem ntau yuav tsum tau nqa tawm hauv ib puag ncig alkaline, thiab kev tswj hwm ntawm cov tshuaj tiv thaiv kub thiab sijhawm muaj cov qauv molecular thiab kev ua tau zoo ntawm cov khoom kawg.

4. HydroxyPropration

Methylated Cellulose ntxiv rov qab nrog acrylates (xws li allyl chloride) los qhia hydroxyprropyl pawg (-ochchch₃). Qhov kev tawm tsam no feem ntau tau nqa tawm hauv kev daws teeb meem alkaline, thiab kev tswj hwm ntawm cov tshuaj tiv thaiv kub thiab cov kev txiav txim siab txiav txim siab hydroxypropyl cov khoom ntawm cov khoom. Cov qib ntawm hydroxypropration ncaj qha cuam tshuam rau solubility, viscosity thiab tshuaj siv lub cev thiab tshuaj lom neeg ntawm HPMC.

5. Neutralization thiab ntxuav

Tom qab cov tshuaj tiv thaiv tau ua tiav, qee cov tshuaj Alkaline lossis cov tshuaj lom neeg uas siv tshuaj lom neeg feem ntau yuav nyob hauv cov kab ke. Yog li ntawd, nws yog ib qho tsim nyog los tshem tawm cov tshuaj uas muaj cov tshuaj lom neeg dhau los ntawm kev kho mob nruab nrab. Neutralation feem ntau nqa tawm nrog cov kua qaub (xws li acetic acid lossis hydrochloric acid lossis hydrochloric acid), thiab ib qho ntsev ntau dua yuav raug tsim tawm tom qab cov kua qaub-hauv paus. Tom qab, impurities nyob rau hauv kev daws teeb meem tau muab tshem tawm los ntawm ntau yam ntxuav kom ntseeg tau qhov kev coj dawb huv ntawm cov khoom lag luam.

6. Lub cev qhuav dej thiab ziab

Lub tshuaj ntxuav cellulose dej yuav tsum qhuav dej, thiab evaporation lossis ultraFiltration feem ntau siv los tshem tawm dej. Kev ncua lub cev qhuav dej yog qhov kev sib txuam ntawm cov teeb meem qhuav, thiab tom qab ntawd nkag mus rau cov txheej txheem kom qhuav. Lub tshuab ziab khaub ncaws yuav ua tshuaj kom qhuav, nqus cua kom qhuav lossis cua kom qhuav. Kev tswj qhov kub thiab txias thaum lub sijhawm ua kom qhuav yog qhov tseem ceeb heev. Kev siab dhau ib qho kub yuav ua rau cov khoom lag luam los thuam lossis poob nws qhov kev ua tau zoo.

7. Crushing thiab sieving

Lub ziab hydroxypropyl methylropenose nyob rau hauv cov hmoov hmoov thiab sifted tswj cov khoom lag luam loj hauv qee qhov ntau. Cov txheej txheem sieving tuaj yeem ua kom cov kev sib txuam ntawm cov khoom lag luam thiab tshem tawm cov impurities nrog cov khoom loj.

8. Ntim thiab cia

Lub txiaj ntsig hydroxypropyf methylcellulose tuaj yeem tsim nyob rau hauv cov ntawv sib txawv raws li cov khoom lag luam tshwj xeeb rau cov khoom lag luam los ntawm kev nqus dej noo thiab cuam tshuam nws cov kev ua tau zoo. Cov khoom ntim tau yuav tsum muab cia rau hauv ib puag ncig qhuav thiab txias kom tsis txhob kub thiab av noo.

9. Tswjhwm Zoo

Yuav tsum muaj kev tswjhwm nruj rau txhua qhov txuas hauv cov txheej txheem ntau lawm los xyuas kom meej tias cov khoom kawg tau raws cov qauv. Cov kev ntsuas uas nquag muaj xws li: solubility, viscosity, pH nqi, impurure cov ntsiab lus. Cov khoom ntawm cov khoom ncaj qha cuam tshuam rau nws cov nyhuv hauv cov ntawv thov sib txawv, yog li kev tswj tau zoo nyob rau hauv kev tsim cov hydroxypropylencellulose.

Cov txheej txheem ntau lawm ntawmHydroxyPropyyl MethylcelluloseKoom nrog ntau yam tshuaj lom neeg thiab kev kho lub cev, thiab muaj cov kev ua haujlwm siab rau cov txheej txheem txheej txheem. Cov tshuaj tiv thaiv kub, sijhawm, Py nqi thiab lwm yam nqi yuav tsum raug tswj nruj me ntsis hauv kev tsim khoom nrog kev ua tau zoo tagnrho. Nrog kev nce qib ntawm kev tshawb fawb thiab thev naus laus zis thiab kev txhim kho kev tsim khoom siv HPMC yog txhim kho tas li, thiab daim ntawv thov teb ntawm cov khoom kuj tseem nthuav dav.