Puas yog hypromellose muaj teeb meem rau lub cev?

Hypromellose, tseem hu ua hydroxypropyl methylcellulose, yog ib tug semi-synthetic, inert, thiab dej-soluble polymer dav siv nyob rau hauv ntau yam lag luam. Nws yog feem ntau siv los ua zaub mov additive, thickener, emulsifier, thiab raws li ib tug kws excipient nyob rau hauv zus tau tej cov ntsiav tshuaj, tsiav tshuaj, thiab ophthalmic npaj. Hauv tsab xov xwm no, peb yuav tshawb txog kev nyab xeeb ntawm hypromellose thiab nws cov teebmeem kev noj qab haus huv.

Kev nyab xeeb ntawm Hypromellose

Hypromellose feem ntau suav hais tias muaj kev nyab xeeb rau kev noj los ntawm ntau yam kev tswj hwm, suav nrog Tebchaws Meskas Food and Drug Administration (FDA), European Food Safety Authority (EFSA), thiab Koom Tes FAO / WHO Cov Kws Lij Choj ntawm Cov Khoom Noj Ntxiv (JECFA). Nws raug cais raws li GRAS (feem ntau lees paub tias muaj kev nyab xeeb) cov khoom noj khoom haus los ntawm FDA, txhais tau hais tias nws muaj keeb kwm ntev ntawm kev siv zaub mov zoo thiab tsis zoo li yuav ua rau muaj kev phom sij thaum noj ntau npaum li cas.

Hauv kev lag luam tshuaj, hypromellose yog dav siv los ua ib qho kev nyab xeeb thiab muaj txiaj ntsig zoo. Nws tau teev nyob rau hauv Teb Chaws Asmeskas Pharmacopeia thiab yog dav siv nyob rau hauv kev tsim khoom ntawm ob qho tib si khoom thiab kua ntau npaum cov ntaub ntawv. Nws kuj tseem siv tau los ua cov roj nplua nyeem ophthalmic thiab pom tias muaj kev nyab xeeb rau kev siv cov lo ntsiab muag, kua muag dag, thiab lwm yam khoom siv kho qhov muag.

Cov kev tshawb fawb tau pom tias hypromellose muaj qhov ncauj toxicity tsawg thiab tsis nqus los ntawm lub cev. Nws kis tau los ntawm lub plab zom mov yam tsis tau tawg, thiab tawm hauv cov quav. Hypromellose kuj tseem suav hais tias muaj kev nyab xeeb rau kev siv rau cov poj niam cev xeeb tub thiab pub niam mis, nrog rau cov menyuam yaus, tsis paub txog kev phiv.

Muaj peev xwm noj qab haus huv los ntawm Hypromellose

Thaum hypromellose feem ntau suav hais tias muaj kev nyab xeeb rau kev noj, muaj qee qhov cuam tshuam kev noj qab haus huv uas yuav tsum tau xav txog.

Cov teebmeem gastrointestinal

Hypromellose yog cov dej-soluble polymer uas nqus dej thiab tsim cov khoom zoo li gel thaum nws los rau hauv cov kua. Qhov no tuaj yeem ua rau muaj viscosity nyob rau hauv lub plab zom mov, uas tuaj yeem ua rau lub sijhawm hloov pauv ntawm cov zaub mov los ntawm lub plab zom mov. Qhov no tuaj yeem ua rau cem quav, tsam plab, thiab plab tsis xis nyob hauv qee tus neeg, tshwj xeeb tshaj yog tias noj ntau.

Kev ua xua

Kev ua xua rau hypromellose tsis tshua muaj, tab sis lawv tuaj yeem tshwm sim. Cov tsos mob ntawm kev tsis haum tshuaj yuav muaj xws li khaus, khaus, o ntawm lub ntsej muag, daim di ncauj, tus nplaig, los yog caj pas, ua tsis taus pa nyuaj, thiab anaphylaxis (ib qho mob hnyav, muaj feem cuam tshuam txog kev ua xua). Yog tias koj muaj cov tsos mob no tom qab noj hypromellose, nrhiav kev kho mob tam sim ntawd.

Qhov muag Irritation

Hypromellose feem ntau yog siv los ua ophthalmic lubricant nyob rau hauv zus tau tej cov qhov muag tee thiab lwm yam ophthalmic npaj. Thaum nws feem ntau suav hais tias muaj kev nyab xeeb rau kev siv ntawm lub qhov muag, qee cov neeg tuaj yeem ntsib qhov muag khaus lossis lwm yam teebmeem. Cov tsos mob ntawm qhov muag khaus yuav muaj xws li liab, khaus, kub hnyiab, thiab kua muag.

Cov tshuaj sib cuam tshuam

Hypromellose tuaj yeem cuam tshuam nrog qee cov tshuaj, tshwj xeeb tshaj yog cov uas xav tau ib puag ncig pH tsawg rau kev nqus. Qhov no yog vim hais tias hypromellose tsim ib yam khoom zoo li gel thaum nws los rau hauv kev sib cuag nrog cov kua, uas tuaj yeem ua rau qeeb qeeb ntawm kev sib cais thiab kev nqus ntawm cov tshuaj. Yog tias koj tab tom noj cov tshuaj, suav nrog cov tshuaj noj lossis tshuaj tom khw, nws yog ib qho tseem ceeb uas yuav tau sab laj nrog koj tus kws kho mob ua ntej noj hypromellose lossis lwm yam tshuaj noj.

Xaus

hypromellose raug suav hais tias muaj kev nyab xeeb rau kev noj los ntawm ntau cov cai tswj hwm. Nws yog dav siv los ua khoom noj khoom haus additives, thickener, thiab emulsifier, nrog rau cov tshuaj excipient nyob rau hauv zus tau tej cov ntsiav tshuaj, capsules, thiab ophthalmic npaj.