Hydroxypropylmethylcellulose (HPMC) yog ntau yam thiab ntau yam sib xyaw nrog kev siv thoob plaws ntau yam kev lag luam. Yuav kom nkag siab txog nws cov ntsiab lus, ib tus yuav tsum nkag siab txog nws cov khoom xyaw, kev tsim khoom, thiab keeb kwm.
Cov khoom xyaw ntawm HPMC:
HPMC yog ib tug semi-synthetic polymer muab los ntawm cellulose, ib tug natural polysaccharide pom nyob rau hauv cov nroj tsuag cell phab ntsa. Lub hauv paus tseem ceeb ntawm cellulose yog ntoo pulp lossis paj rwb fiber. Lub synthesis ntawm HPMC koom nrog kev hloov kho cellulose los ntawm cov tshuaj lom neeg cov tshuaj tiv thaiv los ua kom nws muaj txiaj ntsig ntawm cellulose.
Synthetic yam ntawm HPMC ntau lawm:
Etherification txheej txheem:
Kev tsim tawm ntawm HPMC suav nrog etherification ntawm cellulose nrog propylene oxide thiab methyl chloride.
Thaum lub sijhawm ua haujlwm no, pawg hydroxypropyl thiab methyl tau nkag mus rau hauv cov pob txha cellulose, tsim HPMC.
Kev hloov kho tshuaj:
Kev hloov kho tshuaj tau qhia thaum lub sijhawm sib xyaw ua ke hauv HPMC raug cais raws li cov khoom siv hluavtaws semi-synthetic.
Degree ntawm kev hloov pauv (DS) yog hais txog qhov nruab nrab ntawm cov hydroxypropyl thiab methyl pawg hauv ib chav tsev piam thaj hauv cov saw cellulose. Tus nqi DS no tuaj yeem hloov kho thaum lub sijhawm tsim khoom kom tau txais HPMC nrog cov khoom tshwj xeeb.
Industrial ntau lawm:
HPMC yog tsim los ntawm kev lag luam loj los ntawm ntau lub tuam txhab siv tshuaj tiv thaiv tshuaj.
Cov txheej txheem tsim khoom suav nrog cov xwm txheej meej kom ua tiav cov khoom xav tau thiab kev ua haujlwm ntawm cov khoom kawg.
Natural Sources ntawm HPMC:
Cellulose raws li ib tug natural qhov chaw:
Cellulose yog cov khoom siv tseem ceeb ntawm HPMC thiab muaj ntau nyob rau hauv qhov xwm txheej.
Cov nroj tsuag, tshwj xeeb tshaj yog ntoo thiab paj rwb, yog cov nplua nuj ntawm cellulose. Kev rho tawm ntawm cellulose los ntawm cov peev txheej ntuj no pib tsim cov txheej txheem HPMC.
Biodegradability:
HPMC yog biodegradable, muaj ntau yam khoom siv ntuj tsim.
Lub xub ntiag ntawm ntuj cellulose hauv HPMC pab txhawb rau nws cov khoom biodegradable, ua rau nws tus phooj ywg ib puag ncig hauv qee yam kev siv.
Kev siv ntawm HPMC:
tshuaj:
HPMC yog dav siv nyob rau hauv kev lag luam kws tshuaj raws li coating agents, binders thiab sustained-tso matrices nyob rau hauv cov ntsiav tshuaj formulations. Nws biocompatibility thiab tswj cov khoom tso tawm ua rau nws xaiv thawj zaug rau kev xa tshuaj.
Kev tsim kho kev lag luam:
Hauv kev tsim kho, HPMC yog siv los ua tus neeg saib xyuas dej, thickener, thiab teeb tsa lub sijhawm tswj hwm hauv cov khoom siv cement. Nws lub luag haujlwm hauv kev txhim kho kev ua haujlwm thiab adhesion ntawm mortars thiab plasters yog qhov tseem ceeb.
kev lag luam zaub mov:
HPMC yog siv los ua cov thickener thiab gelling tus neeg sawv cev hauv kev lag luam khoom noj.
Nws yog feem ntau siv hauv cov khoom noj xws li cov kua ntses, kua zaub thiab cov khoom ci.
tshuaj pleev ib ce:
Hauv cov tshuaj pleev ib ce, HPMC muaj nyob rau hauv ntau yam khoom xws li cream, tshuaj pleev ib ce, thiab gels, ua raws li thickeners, stabilizers, thiab emulsifiers.
Cov ntawv thov kev lag luam:
HPMC lub versatility txuas mus rau ntau yam kev lag luam daim ntaub ntawv, nrog rau cov xim formulation, adhesives thiab textile ua.
Regulatory status:
GRAS xwm txheej:
Hauv Tebchaws Meskas, HPMC feem ntau lees paub tias muaj kev nyab xeeb (GRAS) rau qee cov ntawv thov hauv zaub mov los ntawm US Food and Drug Administration (FDA).
Cov qauv tshuaj:
HPMC siv nyob rau hauv cov khoom siv tshuaj yuav tsum ua raws li cov qauv tshuaj pharmacopeial xws li Tebchaws Meskas Pharmacopeia (USP) thiab European Pharmacopoeia (Ph. Eur.).
nyob rau hauv xaus:
Nyob rau hauv cov ntsiab lus, hydroxypropyl methylcellulose (HPMC) yog ib tug semi-synthetic polymer muab tau los ntawm tej yam ntuj tso cellulose los ntawm ib tug tswj kev hloov kho cov txheej txheem. Txawm hais tias nws tau dhau los ua kev hloov pauv tseem ceeb, nws cov hauv paus ntsiab lus nyob hauv cov khoom siv ntuj xws li ntoo pulp thiab paj rwb. Cov khoom tshwj xeeb ntawm HPMC ua rau nws muaj txiaj ntsig zoo hauv kev siv tshuaj, kev tsim kho, khoom noj, tshuaj pleev ib ce thiab ntau yam kev lag luam. Kev sib xyaw ntawm ntuj cellulose thiab kev hloov kho hluavtaws ua rau nws muaj ntau yam, biodegradability thiab kev tswj hwm kev lees paub hauv ntau qhov chaw.
Post lub sij hawm: Dec-18-2023