HydroxyPropyyl methylcellulose (HPMC) yog dej-soluble polymer compound tau los ntawm kev hloov tshuaj lom neeg ntawm ntuj cog cellulose. Nws muaj solubility zoo, ruaj khov thiab biocompatibility, thiab tau siv dav hauv cov zaub mov, tshuaj, kev tsim kho, tshuaj pleev ib ce thiab lwm thaj teb. Cov hauv qab no yuav qhia cov qauv kev npaj, kev npaj, cov ntawv thov tseem ceeb thiab nws qhov zoo thiab qhov tsis zoo ntawm HPMC hauv kev nthuav dav.
1. Tshuaj Txhuam Cov Qauv thiab Khoom
Cov qauv yooj yim ntawm HPMC yog muab tau los ntawm cov cellulose ntuj. Ntawm nws cov molecular chart, qee pawg hydroxyl (-oh) yog hloov los ntawm methyl pawg (-ch3) thiab hydroxyprodropyl pawg (-ch2chohch3). Nws cov qauv tshuaj tshwj xeeb yog tsim los ntawm etherification tshuaj tiv thaiv ntawm cellulose tshuaj, uas muab nws zoo solubility, thickening thiab zaj duab xis-ua cov khoom.
Cov dej ua yeeb yaj kiab ntawm HPMC yog ze ze rau cov degree ntawm kev hloov chaw ntawm methyl thiab hydroxypropropyl hauv cov molecule. Feem ntau, HPMC muaj cov yam ntxwv hauv qab no:
Cov dej ua kom zoo solubility;
Zoo ruaj khov, muaj zog tiv thaiv kom kub thiab kua qaub thiab alkali;
Siab viscosity, muaj zog thickening cov nyhuv;
Vim nws cov qauv tshuaj lom neeg, HPMC tseem tuaj yeem ua ib zaj duab xis thiab muaj ib qho kev tswj hwm kev cuam tshuam rau cov tshuaj lossis lwm yam tshuaj.
2. Npaj txoj kev
Kev npaj ntawm HPMC yog ua tiav los ntawm lub etherification tshuaj tiv thaiv ntawm cellulose. Cellulose ua ntej rov qab nrog methyl chloride (ch3Cl) thiab hydrokypropyl chloride (c3h7och2cl) kom tau txais methylated thiab hydroxypropylated khoom. Ua raws li cov tshuaj tiv thaiv (xws li qhov kub, cov kev xav ntawm cov khoom nyoos, thiab lwm yam) thiab tshuaj lom neeg ntawm HPMC tuaj yeem hloov kho. Cov kauj ruam tshwj xeeb yog raws li hauv qab no:
Cellulose yog yaj los tshem tawm impurities.
Rov qab nrog methyl chloride thiab hydroxypropyl chloride nyob rau hauv ib qho kev daws teeb meem alkaline rau kev tawm tsam herherification.
Cov khoom lag luam HPM kawg yog tau los ntawm kev sib nrauj, pom kev, ziab, kom qhuav thiab lwm cov kauj ruam.
3. Thov Teb
3.1Kws Tshuaj
Hauv kev lag luam kws tshuaj, HPMC tau dav siv ua ib qho kev zam rau cov tshuaj. Nws tsis yog tsuas yog siv los ua cov tuab dua, tab sis kuj tuaj yeem siv los npaj tswj cov tshuaj npaj. Nws cov dej zoo heev solubility thiab biocompatibility ua nws ib qho tseem ceeb hauv kev npaj khoom lag luam xws li ntsiav tshuaj, tsiav tshuaj, thiab tshuaj noj. Cov ntawv thov feem muaj xws li:
Tshuaj Nrog Yeeb Tshuaj: HPMC tuaj yeem nkag mus rau hauv lub cev thiab tso cov tshuaj, yog li nws feem ntau siv los npaj cov tshuaj tawm.
Cov neeg nqa tshuaj yeeb: HPMC tuaj yeem raug siv los ua cov cab kuj rau moulding thiab dispersion thaum npaj tshuaj ntsiav, ntsiav tshuaj, granules thiab lwm cov ntaub ntawv ntau npaum li cas.
Gel: HPMC tuaj yeem siv los ua cov gel los npaj cov ntaub ntawv tso quav ntawm ntau yam tshuaj, xws li tshuaj pleev ib ce.
3.2 Khoom Noj Khoom Haus
HPMC tseem muaj dav nyob rau hauv kev lag luam khoom noj khoom haus, tsuas yog txhawm rau txhim kho kev ntxhib los mos, txuas lub txee lub neej, thiab txhim kho cov zaub mov saj. Cov ntawv thov feem muaj xws li:
Thickener thiab stabilizer: HPMC tuaj yeem siv ua cov ntaub tuab hauv cov zaub mov xws li cov khaub noom, zaub xam lav kom nce viscosity thiab ruaj khov ntawm cov zaub mov.
Tus neeg sawv cev rau tus neeg sawv cev: Hauv qee cov zaub mov, HPMC tuaj yeem siv ua tus sawv cev rau tus neeg ua haujlwm los muab cov txiaj ntsig gel zoo.
Mov ci thiab ncuav mog qab zib: HPMC tuaj yeem txhim kho cov saj ntawm qhob cij thiab pastries, nce lawv noo noo thiab maj mam ua kom qhuav cov zaub mov.
3.3 Kev Tsim Kho Kev Lag Luam
HPMC tsuas yog siv los ua cov ntaub ntawv tuab thiab dej-khaws cia rau cov ntaub ntawv tsim tsev xws li Cementum, thiab feem ntau siv hauv kev tsim kho hauv qab no:
Tshuaj khib: HPMC tuaj yeem txhim kho cov nplaum, kev tshuaj khib nyiab thiab kev tshuaj khib, thiab txhim kho kev tsim kho ntawm kev tshuaj khib.
Pobzeb nplaum: HPMC tuaj yeem txhim kho kev tsim kho cov khoom siv vuas nplaum thiab txhim kho nws txoj kev ua haujlwm.
Xim: Siv HPMC hauv cov xim tha xim tuaj yeem nce viscosity thiab ruaj khov ntawm cov xim, thiab pab tswj cov xim ntawm cov xim.
3.4 Cov Tshuaj Pleev Kev Lag Luam
Hauv cov tshuaj pleev ib ce, HPMC feem ntau yog siv ua cov tuab, emulsifier thiab ua yeeb yaj kiab, ntsej muag tshuaj ntxuav tes, plaub hau tshuaj, plaub hau ci. Nws cov haujlwm muaj xws li:
Thickener: HPMC tuaj yeem nce viscosity ntawm cov tshuaj pleev ib ce thiab txhim kho kev xav siv.
Moisturizer: HPMC muaj cov khoom muaj zoo moisturizing thiab tuaj yeem pab ntsuas kom noo noo kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij ua kom cov tawv nqaij.
Emulsifier: HPMC tuaj yeem pab dej thiab roj sib tov los ua cov emulsion ruaj khov.
4. Qhov zoo thiab kev soj ntsuam tsis zoo
4.1 zoo
Zoo biocompatibility: HPMC yog cov khoom ntuj hloov kho, feem ntau tsis muaj tshuaj lom thiab tsis muaj kev phom sij rau tib neeg lub cev, thiab muaj kev zoo biocompatibility.
Cov suteless thiab ntxhiab tsw: HPMC feem ntau tsis muaj ntxhiab tsw lossis khaus thiab yog qhov tsim nyog rau cov zaub mov thiab tshuaj.
Siv dav siv: Vim nws cov dej ua haujlwm zoo, thickening thiab ruaj khov, hpm yog siv dav hauv ntau qhov kev lag luam.
4.2 Cov Kev Tsis Txaus Siab
Tsis ruaj khov ntawm qhov siab kub: txawm hais tias HPMC muaj qhov zoo thermal ruaj khov, nyob rau hauv hydrolyze thiab abrade, poob qee yam ntawm nws cov haujlwm.
Tus nqi siab: piv nrog qee cov khoom siv thickeners, HPMC yog kim dua, uas yuav txwv nws siv hauv qee cov ntawv thov.
Raws li cov polymer zoo heev,HPMC tau siv dav hauv cov tshuaj, khoom noj, kev tsim kho, tshuaj pleev ib ce thiab lwm thaj chaw vim nws cov dej solubility zoo, biocompatibility thiab ruaj khov. Nrog rau kev txhim kho kev tshawb fawb thiab thev naus laus zis thiab kev tsim kho txuas ntxiv ntawm kev xav tau, daim teb ntawm HPMC yuav txuas ntxiv mus ua si lub luag haujlwm ntau dua.
Lub Sijhawm Post: Feb-17-2025