HPMC Hypromellose

Hydroxypropyl Methylcellulose(HPMC), yog ntau yam tshuaj sib xyaw nrog cov mis [C6H7O2(OH)3-mn(OCH3)m(OCH2CH(OH)CH3)n]x, qhov twg m sawv cev rau qib ntawm methoxy hloov thiab n sawv cev rau qib ntawm hydroxypropoxy. hloov. Nws yog muab los ntawm cellulose, ib tug natural polymer tau los ntawm lub cell phab ntsa ntawm cov nroj tsuag. HPMC tsis muaj ntxhiab, tsis qab, thiab tsis muaj tshuaj lom. Nws muaj ntau yam physicochemical zog xws li solubility hauv dej, thermal gelation zog, thiab muaj peev xwm tsim cov yeeb yaj kiab, ua rau nws siv dav hauv ntau lub lag luam.

Hauv kev lag luam kws tshuaj, HPMC feem ntau siv los ua ib qho khoom noj khoom haus-ib yam khoom tsim nrog rau cov khoom xyaw nquag ntawm cov tshuaj, rau lub hom phiaj ntawm kev ruaj khov mus ntev, bulking li khoom formulations uas muaj cov khoom xyaw muaj zog hauv me me (yog li feem ntau xa mus rau raws li ib tug muab tub lim, diluent, los yog carrier), los yog txhim khu kev nqus los yog solubility. HPMC capsules yog lwm txoj hauv kev rau gelatin capsules rau cov neeg tsis noj nqaij thiab yog siv rau hauv kev tswj-tso formulations, tso cai rau kev tso tawm qeeb ntawm ib lub sijhawm. HPMC cov kev daws teeb meem tseem tuaj yeem ua cov viscolyzers kom nce viscothlmic ntawm cov kev daws teeb meem ophthalmic, txhim kho lub sijhawm nyob hauv lub sijhawm ntawm cov tshuaj ntawm qhov chaw hauv qab.

Hauv kev lag luam khoom noj khoom haus, HPMC tau lees paub tias yog khoom noj khoom haus zoo (E464) thiab ua haujlwm ntau yam xws li emulsifier, thickening agent, thiab stabilizer. Nws yog ua haujlwm nyob rau hauv kev tsim khoom ntawm ntau yam khoom noj los txhim kho kev ntxhib los mos, khaws cov dej noo, thiab tsim cov yeeb yaj kiab uas siv tau. Cov cuab yeej thermal gelation ntawm HPMC yog qhov tshwj xeeb tshaj yog nyob rau hauv daim ntawv thov uas yuav tsum tau gelling ntawm qhov kub thiab txias, xws li hauv cov zaub mov tsis noj nqaij thiab vegan uas nws tuaj yeem hloov tau gelatin. HPMC kuj tseem txhawb nqa lub neej txee thiab zoo ntawm cov khoom ci, kua ntses, thiab khoom qab zib los ntawm kev tswj cov crystallization thiab noo noo.

Kev tsim kho kev lag luam tau txais txiaj ntsig los ntawm HPMC hauv kev tsim cov khoom siv hauv tsev. Nws cov ntawv thov suav nrog kev ua tus tuav ntaub ntawv thiab dej tuav tus neeg sawv cev hauv mortars, plasters, thiab coatings, txhim kho kev ua haujlwm, txo kev siv dej, thiab ncua sijhawm qhib - lub sijhawm uas cov khoom siv tseem siv tau. HPMC txhim kho cov khoom ntawm cov cement-based formulations, muab zoo adhesion, kis tau, thiab tsis kam mus sagging.

Hauv kev lag luam tshuaj pleev ib ce thiab kev saib xyuas tus kheej, HPMC ua haujlwm ua tus neeg ua yeeb yaj kiab, emulsifier, thiab rheology hloov kho hauv cov khoom xws li tshuaj pleev, tshuaj pleev, thiab plaub hau gels. Nws compatibility nrog ntau hom ntawm daim tawv nqaij thiab muaj peev xwm stabilize emulsions txhim khu cov khoom ua tau zoo thiab lub neej ntev. HPMC's hydration zog ua rau nws muaj cov khoom siv kho mob hauv daim tawv nqaij, pab khaws cov dej noo thiab muab kev xav zoo. Hauv cov ntsiab lus, HPMC qhov kev siv ntau yam nthuav dav cov tshuaj, khoom noj, kev tsim kho, thiab tshuaj pleev ib ce, qhia txog nws qhov tseem ceeb raws li cov khoom muaj ntau yam hauv ntau daim ntawv thov.