Yuav ua li cas txhawm rau txhim kho cov dej khaws cia ntawm hydroxypropy kas methylcellose?

1. Nce cov qib ntawm kev hloov pauv (DS) thiab cov hniav xoo liab (MS) ntawm HPMC
Cov qib kawm ntawm cov pab pawg hydroxypropyl thiab methoxy pawg ntawmHPMCcuam ​​tshuam ncaj qha cuam tshuam nws lub peev xwm kav dej. Ib qib siab dua ntawm kev hloov pauv yuav txhim kho nws cov adsorption muaj peev xwm rau dej lwg me thiab txhim kho cov dej ua kom ruaj khov. Yog li, thaum lub sijhawm cov txheej txheem tsim khoom ntawm hydroxypropyl thiab methoxy pawg yuav tau nce qib hpmc muaj kev ua haujlwm zoo dua.

2. Txhim kho qhov hnyav molecular ntawm HPMC
Lub cev hnyav molecular ntawm HPMC yuav cuam tshuam rau cov viscosity thiab dej retentive muaj peev xwm ntawm nws cov kev daws teeb meem. Feem ntau hais lus, HPMC nrog qhov hnyav molecular loj tuaj yeem tsim cov tshuaj hnoos ntau dua, yog li kev txhim kho kev ua kom muaj peev xwm ua kom muaj peev xwm ua kom muaj peev xwm ua kom muaj peev xwm ua kom muaj peev xwm ua kom muaj peev xwm ua kom muaj peev xwm ua kom tiav. Yog li ntawd, qib degree ntawm polymerization ntawm HPMC tuaj yeem tswj tau nws ib qho haum molecular hnyav kom ua tiav cov dej khov zoo.

3. Kho cov viscosity ntawm hpmc
Lub viscosity ntawm Kimacell®HPMC muaj qhov cuam tshuam tseem ceeb ntawm kev ua kom muaj dej. High-viscosity HPMC tuaj yeem tsim cov dej muaj zog-khaws cia rau saum npoo ntawm lub substrate, txo cov dej evaporation, thiab txhim kho cov dej evaporation. Hauv daim ntawv thov ntawm cov ntaub ntawv tsim tsev (xws li culture thiab putty hmoov), nruab nrab-siab viscosity HPMC feem ntau raug xaiv kom tau txais cov dej zoo dua.

4. Txhim kho cov particle loj ntawm HPMC
Lub particle loj ntawm HPMC cuam tshuam nws qhov kev cais tawm thiab kev ua kom muaj zog. Finer HPMC hmoov dissolves ntau tusyees hauv dej, sai sai ua ib qho kev sib xyaw kom zoo, thiab txhim kho cov dej khaws cia. Yog li ntawd, nyob rau hauv cov txheej txheem ntau lawm, trafine sib tsoo tshuab yuav siv tau los ua HPMC muaj qhov me me loj dua, yog li txhim kho dej muaj peev xwm ua kom tau txais dej khov.

5. Tswj txoj kev xaus ntawm HPMC
Qhov kawg ntawm HPMC cuam tshuam nws qhov kev tsis txaus siab thiab ua yeeb yaj kiab ua yeeb yam hauv daim ntawv thov. Yog hpmc dissolves sai dhau lawm, nws yuav ua rau kev hloov pauv dej nrawm, yog li txo dej ua kom muaj kev ua tau zoo. Yog li no, lub Tsib Hlis Qib HPMC tuaj yeem hloov kho lossis qeeb tawm qeeb tuaj yeem qhia nws cov kev sib cais hauv cov dej sib cais, yog li kev txhim kho cov nyhuv khaws cia.

6. Nce lub thermal gelation kub ntawm HPMC
HPMC muaj cov khoom siv thermal gelation. Thaum qhov ntsuas kub tshaj qhov muaj nuj nqis, nws yuav ua rau cov gel thiab tso dej. Yog li ntawd, ua kom lub thermal kub ntawm HPMC (piv txwv li, qhov ntsuas kub ntawm HPMC pib ua kom nws muaj peev xwm ua kom tau dej zoo nyob rau hauv ib puag ncig kub. Feem ntau, cov thermal gelation kub ntawm HPMC tuaj yeem nce los ntawm kev kho cov qib hloov pauv thiab hnyav hnyav ntawm HPMC.

7. Suav nrog lwm cov dej polymer khaws cov neeg sawv cev
HPMC tuaj yeem sib txuas nrog lwm cov ntaub ntawv polymer (xws li cov pa roj polyvinyl pva, xanthan ntawm cov pos hniav PVA, Xanthan ntawm cov pos hniav PLA, XANTHANS, GAS, thiab lwm yam) txhawm rau txhim kho nws cov dej khaws cia. Piv txwv li, hauv cov hmoov nplej thiab cov hmoov ntawm cov hmoov liab redispersible looj tes (RDP) lossis roj hmab ua kom zoo nkauj

8. Txhim kho qhov tawg ntawm HPMC
HPMC yooj yim rau agglomerate thaum siv, cuam tshuam rau nws cov khaub ncaws tsis sib xws, yog li txo cov dej ua kom ruaj khov. Yog li ntawd, tsim nyog kev kho cov txheej txheem rau saum toj (xws li ntxiv cov ntsev me me, yog li HPMC mluav ntau tusyees hauv dej, yog li kev txhim kho nws lub peev xwm kav dej.

9. Xaiv cov qauv HPMC haum
Cov qauv sib txawv ntawm HPMC muaj cov khoom siv sib txawv. Hauv cov teb sib txawv xws li cov ntaub ntawv hauv tsev, cov khoom siv, thiab tshuaj, tus qauv HPMC tsim nyog yuav tsum raug xaiv. Piv txwv li, hauv kev tsim lub tsev cug, cov viscos muaj nyob ib txwm raug xaiv, thaum nyob hauv cov tshuaj ntsuab, thaum zoo dua solubility ua tau kom muaj kev ruaj ntseg ntawm kev siv yeeb tshuaj.

10. Txhim kho cov ntawv thov ib puag ncig ntawm HPMC
Cov dej ua tiav kev ua tau zoo ntawm Kimacell® kuj cuam tshuam los ntawm ib puag ncig cov khoom xws li kub, av noo, thiab cov khoom piv. Piv txwv li, nyob rau hauv qhov kev kub ntxhov, cov neeg HPMC ntxiv lossis siv cov qauv ntawm cov neeg muaj kuab kom muaj peev xwm ua kom muaj kev ruaj ntseg zoo. Nyob rau tib lub sijhawm, tswj hwm cov dej-xiss piv thiab kho lwm cov khoom xyaw lossis dej tshauv kom txhim kho cov dej ua haujlwm hauv HPMC.

Txhim kho cov dej tuav tsegHydroxyPropyyl methylcellulose (HPMC)Yuav tsum tau ua kom zoo dua los ntawm ntau yam xws li molecular qauv, cov khoom siv lub cev, thiab cov ntawv thov. Los ntawm kho cov tsis muaj xws li qib degree ntawm kev hloov chaw, viscosity loj, thiab sib xyaw ua ke tsim kho kom tau raws li cov kev xav tau ntawm cov kev xav tau ntawm cov kev xav tau ntawm cov kev xav tau ntawm cov kev xav tau ntawm cov kev xav tau ntawm cov kev xav tau ntawm cov kev xav tau ntawm cov kev xav tau ntawm cov kev xav tau sib txawv.