Txoj kev Dissolution ntawm (Hydroxypropyl Methyl Cellulose) HPMC

Kev tawg ntawm Hydroxypropyl Methylcellulose (HPMC) feem ntau yuav cuam tshuam cov hmoov polymer hauv dej raws li kev tswj xyuas kom muaj dej kom zoo thiab kev sib cais. Nov yog ib txoj hauv kev rau kev rhuav tshem HPMC:

Cov ntaub ntawv xav tau:

1. HPMC hmoov
2. Distilled los yog deionized dej (rau qhov zoo tshaj plaws)
3. Sib tov lub nkoj los yog thawv
4. stirrer los yog mixing apparatus
5. Cov cuab yeej ntsuas (yog tias yuav tsum tau txhaj koob tshuaj meej)

Txheej txheem Dissolution:

1. Npaj Cov Dej: Ntsuas qhov xav tau ntawm cov dej distilled lossis deionized raws li qhov xav tau ntawm HPMC tov. Nws yog ib qho tseem ceeb uas yuav tsum tau siv cov dej zoo los tiv thaiv impurities los yog cov kab mob tsis zoo los ntawm kev cuam tshuam cov txheej txheem kev sib cais.
2. Tshav Kub Dej (Yeem): Yog tias tsim nyog, ua kom sov cov dej mus rau qhov kub ntawm 20 ° C mus rau 40 ° C (68 ° F txog 104 ° F) kom yooj yim rau kev tawg. Cov cua kub tuaj yeem ua kom cov dej ntws ntawm HPMC thiab txhim kho qhov tawg ntawm cov khoom siv polymer.
3. Maj mam ntxiv HPMC Powder: Maj mam ntxiv HPMC hmoov rau hauv dej thaum nplawm tas li kom tsis txhob clumping lossis agglomeration. Nws yog ib qho tseem ceeb uas yuav tsum tau ntxiv cov hmoov maj mam kom ntseeg tau tias tsis sib xws thiab tsis txhob tsim cov pob.
4. Ntxiv stirring: Tswj stirring los yog agitation ntawm cov sib tov kom txog thaum HPMC hmoov yog dispersed tag thiab hydrated. Qhov no feem ntau yuav siv sij hawm ob peb feeb, nyob ntawm seb qhov luaj li cas ntawm cov hmoov HPMC thiab cov stirring ceev.
5. Tso dej: Tom qab ntxiv HPMC hmoov, tso cai rau cov sib tov kom sawv ntsug rau lub sij hawm txaus los xyuas kom meej hydration ntawm cov polymer. Qhov no yuav muaj li ntawm 30 feeb mus rau ob peb teev, nyob ntawm seb cov qib thiab cov particle loj ntawm HPMC.
6. Kho pH (yog tias tsim nyog): Nyob ntawm daim ntawv thov, koj yuav tsum tau kho cov pH ntawm HPMC tov siv cov kua qaub los yog alkali daws. Cov kauj ruam no yog qhov tseem ceeb tshwj xeeb rau cov ntawv thov uas pH rhiab heev yog qhov tseem ceeb, xws li hauv cov tshuaj lossis kev kho tus kheej.
7. Lim (yog tias tsim nyog): Yog tias cov tshuaj HPMC muaj cov khoom tsis sib xws lossis cov khoom tsis sib xyaw ua ke, nws yuav tsim nyog los lim cov tshuaj siv cov ntxaij lim dej zoo lossis cov ntawv lim kom tshem tawm cov khoom seem.
8. Khaws lossis Siv: Thaum HPMC tau yaj tag nrho thiab muaj dej, cov tshuaj tau npaj rau kev siv. Nws tuaj yeem khaws cia rau hauv lub thawv kaw lossis siv tam sim ntawd hauv ntau daim ntawv thov xws li tshuaj, tshuaj pleev ib ce, khoom siv, lossis khoom noj khoom haus.

Nco tseg:

• Tsis txhob siv dej los yog dej uas muaj cov ntxhia hauv cov ntsiab lus siab, vim tias nws yuav cuam tshuam rau cov txheej txheem kev sib cais thiab kev ua haujlwm ntawm HPMC cov tshuaj.
• Lub sij hawm dissolution thiab kub tej zaum yuav txawv nyob ntawm seb cov qib tshwj xeeb, particle loj, thiab viscosity qib ntawm HPMC hmoov siv.
• Nco ntsoov ua raws li cov chaw tsim khoom cov lus pom zoo thiab cov lus qhia rau kev npaj HPMC cov kev daws teeb meem, vim cov qib sib txawv yuav muaj cov cai tshwj xeeb rau kev sib cais.