Qhov sib txawv ntawm HPS thiab HPMC
Hydroxypropyl hmoov txhuv nplej siab(HPS) thiabHydroxypropyl methyl cellulose(HPMC) yog ob feem ntau siv polysaccharides hauv ntau daim ntawv thov kev lag luam, suav nrog tshuaj, khoom noj, thiab kev tsim kho. Txawm hais tias lawv zoo sib xws, HPS thiab HPMC muaj qhov sib txawv ntawm lawv lub cev thiab tshuaj lom neeg, nrog rau lawv lub luag haujlwm. Hauv tsab xov xwm no, peb yuav tshawb txog qhov sib txawv ntawm HPS thiab HPMC hais txog lawv cov qauv tshuaj, khoom siv, thiab kev siv.
Chemical Structure
HPS yog cov hmoov txhuv nplej siab uas tau txais los ntawm kev hloov kho cov hmoov txhuv nplej siab nrog hydroxypropyl pawg. Cov pab pawg hydroxypropyl txuas nrog cov pab pawg hydroxyl ntawm cov hmoov txhuv nplej siab, ua rau cov hmoov txhuv nplej siab hloov kho nrog kev txhim kho solubility thiab ruaj khov. HPMC, ntawm qhov tod tes, yog cellulose derivative uas tau los ntawm kev hloov kho cellulose nrog hydroxypropyl thiab methyl pawg. Cov pab pawg hydroxypropyl txuas mus rau cov pab pawg hydroxyl ntawm cov cellulose molecule, thaum cov methyl pawg txuas nrog cov tshuaj anhydroglucose.
Cov khoom
HPS thiab HPMC muaj cov khoom sib txawv ntawm lub cev thiab tshuaj lom neeg uas ua rau lawv haum rau kev siv sib txawv. Cov yam ntxwv ntawm HPS muaj xws li:
- Solubility: HPS yog soluble hauv dej thiab tuaj yeem tsim cov kev daws teeb meem ntawm qhov tsis tshua muaj siab.
- Viscosity: HPS muaj viscosity tsawg piv rau HPMC thiab lwm yam polysaccharides.
- Kev ruaj ntseg: HPS yog ruaj khov ntawm ntau qhov kub thiab txias thiab pH qib thiab tiv taus cov enzymes thiab lwm yam degradative agents.
- Gelation: HPS tuaj yeem tsim cov gels thermally thim rov qab ntawm qhov siab, uas ua rau nws haum rau ntau yam khoom noj thiab tshuaj siv.
Cov khoom ntawm HPMC muaj xws li:
- Solubility: HPMC yog soluble hauv dej thiab tsim cov kev daws teeb meem ntawm qhov tsis tshua muaj siab.
- Viscosity: HPMC muaj qhov viscosity siab thiab tuaj yeem tsim cov tshuaj viscous txawm nyob rau qhov qis qis.
- Kev ruaj ntseg: HPMC yog qhov ruaj khov ntawm ntau qhov kub thiab txias thiab pH qib thiab tiv taus cov enzymes thiab lwm yam degradative agents.
- Kev muaj peev xwm ua yeeb yaj kiab: HPMC tuaj yeem tsim cov yeeb yaj kiab nyias, hloov tau yooj yim uas muaj txiaj ntsig zoo hauv ntau yam kev siv tshuaj thiab tshuaj pleev ib ce.
Daim ntawv thov
HPS thiab HPMC muaj cov ntawv thov sib txawv vim lawv cov khoom sib txawv. Cov kev siv ntawm HPS suav nrog:
- Khoom noj khoom haus: HPS yog siv los ua thickener thiab stabilizer nyob rau hauv ntau yam khoom noj khoom haus, xws li kua ntses, kua zaub, thiab hnav khaub ncaws.
- Pharmaceutical: HPS yog siv los ua ib qho kev sib khi thiab disintegrant hauv cov ntsiav tshuaj thiab tshuaj ntsiav thiab ua lub tsheb rau kev xa tshuaj.
- Kev tsim kho: HPS yog siv los ua cov thickener thiab binder hauv cov khoom siv cement, xws li mortar thiab pob zeb.
Cov ntawv thov ntawm HPMC suav nrog:
- Khoom noj khoom haus: HPMC yog siv los ua cov thickener thiab stabilizer nyob rau hauv ntau yam khoom noj khoom haus, xws li ice cream, yogurt, thiab ci.
- Pharmaceutical: HPMC yog siv los ua ib qho kev sib khi, disintegrant, thiab cov neeg ua yeeb yaj kiab hauv cov ntsiav tshuaj thiab cov tshuaj ntsiav thiab ua lub tsheb xa tshuaj.
- Kev Kho Tus Kheej: HPMC yog siv rau hauv ntau yam khoom siv tu tus kheej, xws li tshuaj pleev, tshuaj zawv plaub hau, thiab tshuaj pleev ib ce, ua cov thickener thiab stabilizer.
- Kev tsim kho: HPMC yog siv los ua cov thickener thiab binder hauv cov khoom siv cement, xws li mortar thiab pob zeb, thiab ua cov txheej txheem rau cov khoom siv hauv tsev.
Xaus
Hauv kev xaus, HPS thiab HPMC yog ob lub polysaccharides uas tau siv dav hauv ntau daim ntawv thov kev lag luam. HPS yog cov hmoov txhuv nplej siab uas muaj viscosity tsawg, yog thermally thim rov qab, thiab ruaj khov ntawm ntau qhov kub thiab txias thiab pH. HPMC, ntawm qhov tod tes, yog cov cellulose derivative uas muaj viscosity siab, tuaj yeem tsim cov yeeb yaj kiab nyias, hloov tau yooj yim, thiab tseem ruaj khov ntawm ntau qhov kub thiab pH. Qhov sib txawv ntawm ob lub tebchaw no ua rau lawv tsim nyog rau kev siv ntau yam hauv kev lag luam, suav nrog zaub mov, tshuaj, kev saib xyuas tus kheej, thiab kev tsim kho.
Hais txog lawv cov qauv tshuaj, HPS yog cov hmoov txhuv nplej siab hloov kho uas muaj cov pab pawg hydroxypropyl, thaum HPMC yog hloov kho cellulose uas muaj ob pawg hydroxypropyl thiab methyl. Qhov sib txawv ntawm cov qauv tshuaj no ua rau muaj kev sib txawv ntawm lub cev thiab tshuaj lom neeg ntawm cov khoom sib xyaw, xws li solubility, viscosity, stability, thiab gelation lossis zaj duab xis-tsim muaj peev xwm.
Cov ntawv thov ntawm HPS thiab HPMC kuj txawv vim lawv cov khoom sib txawv. HPS feem ntau yog siv los ua cov thickener thiab stabilizer nyob rau hauv cov khoom noj khoom haus, ib tug binder thiab disintegrant nyob rau hauv pharmaceuticals, thiab ib tug thickener thiab binder nyob rau hauv cov ntaub ntawv tsim kho. Lub caij no, HPMC yog dav siv los ua cov thickener thiab stabilizer nyob rau hauv cov khoom noj khoom haus, ib tug binder, disintegrant, thiab zaj duab xis-tsim tus neeg saib xyuas nyob rau hauv kws tshuaj, ib tug thickener thiab stabilizer nyob rau hauv cov khoom tu tus kheej, thiab ib tug thickener, binder, thiab txheej tus neeg sawv cev nyob rau hauv kev tsim kho cov ntaub ntawv.
Hauv cov ntsiab lus, HPS thiab HPMC yog ob feem ntau siv polysaccharides uas muaj cov qauv tshuaj sib txawv, lub cev thiab tshuaj lom neeg, thiab kev siv hauv ntau yam lag luam. Kev nkag siab qhov sib txawv ntawm ob lub tebchaw no yog qhov tseem ceeb rau kev xaiv cov khoom tsim nyog rau cov kev siv tshwj xeeb thiab ua kom lawv cov kev ua tau zoo hauv ntau yam txheej txheem.
Post lub sij hawm: Mar-18-2023