Qhov txawv ntawm CMC thiab HPMC

Carboxymethyl cellulose (CMC) thiab hydroxypropyl methylcellulose (HPMC) yog ob hom cellulose derivatives uas tau siv dav hauv cov khoom noj, tshuaj, thiab kev tu tus kheej. Thaum ob qho tib si siv los ua thickeners, stabilizers, thiab emulsifiers, muaj qee qhov sib txawv tseem ceeb ntawm CMC thiab HPMC uas ua rau lawv haum rau kev siv sib txawv. Hauv tsab xov xwm no, peb yuav tham txog qhov sib txawv ntawm CMC thiab HPMC hais txog lawv cov qauv tshuaj, khoom siv, kev siv, thiab kev nyab xeeb.

1. Chemical Structure

CMC yog cov dej-soluble polymer uas yog muab los ntawm cellulose, uas yog ib tug natural polymer pom nyob rau hauv cov nroj tsuag cell phab ntsa. Cov qauv tshuaj ntawm CMC yog tus cwj pwm los ntawm cov pawg carboxymethyl (-CH2-COOH) uas txuas nrog cov pob txha cellulose. Qhov degree ntawm kev hloov pauv (DS) ntawm CMC yog hais txog tus naj npawb ntawm carboxymethyl pawg uas tam sim no ib chav tsev anhydroglucose (AGU) ntawm cov pob txha cellulose. DS ntawm CMC tuaj yeem nyob ntawm 0.2 txog 1.5, nrog rau cov txiaj ntsig DS siab dua qhia tau tias muaj kev hloov pauv ntau dua.

HPMC kuj yog ib qho dej-soluble polymer uas tau los ntawm cellulose. Txawm li cas los xij, tsis zoo li CMC, HPMC tau hloov kho nrog hydroxypropyl thiab methyl pawg. Cov pab pawg hydroxypropyl (-OCH2CHOHCH3) txuas rau cov pab pawg hydroxyl ntawm cov pob txha cellulose, thaum cov methyl pawg (-CH3) txuas nrog cov pab pawg hydroxypropyl. Qib ntawm kev hloov pauv ntawm HPMC yog hais txog tus naj npawb ntawm hydroxypropyl thiab methyl pawg uas muaj nyob rau hauv AGU ntawm cov pob txha cellulose. DS ntawm HPMC tuaj yeem nyob ntawm 0.1 txog 3.0, nrog rau cov txiaj ntsig DS siab dua qhia tau tias muaj kev hloov pauv ntau dua.

2. Cov khoom

CMC thiab HPMC muaj cov khoom sib txawv uas ua rau lawv haum rau kev siv sib txawv. Qee cov khoom tseem ceeb ntawm CMC thiab HPMC tau teev tseg hauv qab no:

ib. Solubility: CMC yog heev soluble nyob rau hauv dej thiab cov ntaub ntawv ntshiab, viscous daws. HPMC kuj tseem muaj cov dej soluble hauv dej, tab sis cov kev daws teeb meem yuav turbid nyob ntawm qhov kev hloov pauv.

b. Rheology: CMC yog cov khoom siv pseudoplastic, uas txhais tau hais tias nws nthuav tawm tus cwj pwm shear thinning. Qhov no txhais tau hais tias cov viscosity ntawm CMC txo qis raws li tus nqi shear nce. HPMC, ntawm qhov tod tes, yog cov khoom siv Newtonian, uas txhais tau hais tias nws cov viscosity tseem nyob tas li tsis hais tus nqi txiav.

c. Film-forming zog: CMC muaj cov yeeb yaj kiab zoo, uas ua rau nws tsim nyog siv rau hauv cov txheej txheem thiab cov yeeb yaj kiab. HPMC kuj muaj cov khoom ua yeeb yaj kiab, tab sis cov yeeb yaj kiab yuav nkig thiab ua rau tawg.

d. Stability: CMC yog ruaj khov nyob rau ntau yam ntawm pH thiab kub tej yam kev mob. HPMC kuj tseem ruaj khov nyob rau ntau qhov pH, tab sis nws qhov kev ruaj ntseg yuav cuam tshuam los ntawm qhov kub thiab txias.

3. Siv

CMC thiab HPMC tau siv dav hauv ntau daim ntawv thov hauv cov khoom noj, tshuaj, thiab kev saib xyuas tus kheej. Qee qhov kev siv tseem ceeb ntawm CMC thiab HPMC tau teev tseg hauv qab no:

ib. Kev lag luam khoom noj khoom haus: CMC feem ntau yog siv los ua cov thickener, stabilizer, thiab emulsifier hauv cov khoom noj xws li ice cream, salad dressings, thiab ci. HPMC kuj tseem siv los ua cov thickener thiab stabilizer hauv cov khoom noj khoom haus, tab sis feem ntau yog siv los ua cov txheej txheem rau cov khoom qab zib xws li gummy candies thiab chocolates.

b. Kev lag luam kws tshuaj: CMC yog siv los ua ib qho kev sib khi, disintegrant, thiab ntsiav tshuaj txheej tus neeg sawv cev hauv cov tshuaj formulations. HPMC kuj tseem siv los ua ib qho kev sib khi, disintegrant, thiab ntsiav tshuaj txheej tus neeg sawv cev hauv cov tshuaj formulations.