Hydroxyethylcellulose (HEC) yog cov dej-soluble polymer dav siv nyob rau hauv ntau yam kev lag luam thiab cov khoom siv niaj hnub, tshwj xeeb tshaj yog hauv cov khoom tu tus kheej thiab cov tshuaj ntxuav tes. Nws muaj cov thickening zoo, tshem tawm, emulsifying, zaj duab xis-tsim thiab tiv thaiv colloid zog, yog li nws yog feem ntau siv raws li ib tug thickener nyob rau hauv kua xab npum.
1. Cov qauv thiab cov khoom ntawm hydroxyethyl cellulose
HEC yog ib qho derivative nonionic tau los ntawm cellulose los ntawm etherification cov tshuaj tiv thaiv thiab muaj zog hydration muaj peev xwm thiab hydrophilicity. Cov saw hlau molecular ntawm HEC muaj ntau pawg hydroxyethyl hloov cov hydrogen atoms ntawm natural cellulose, tsim ib tug series ntawm cov saw ntev molecular lug. Cov qauv molecular no tso cai rau HEC kom sai sai hauv dej los tsim cov kua dej tsis sib xws.
Ib qho khoom tseem ceeb ntawm HEC yog nws qhov kev hloov pauv mus rau qhov sib txawv pH qhov tseem ceeb. Nws tuav nws cov nyhuv thickening tshaj pH ntau yam, muab nws qhov zoo tshaj plaws hauv cov khoom xws li kua xab npum, uas yuav muaj ntau yam khoom xyaw thiab pH hloov. Tsis tas li ntawd, HEC kuj muaj biocompatibility zoo thiab kev nyab xeeb, thiab yog tsim rau siv nyob rau hauv ntau yam khoom uas tuaj rau hauv kev sib cuag nrog tib neeg lub cev, xws li kua xab npum, tshuaj zawv plaub hau, thiab lwm yam.
2. Thickening mechanism ntawm hydroxyethyl cellulose hauv kua xab npum
Nyob rau hauv cov kua xab npum formulations, lub ntsiab mechanism ntawm kev txiav txim ntawm HEC raws li ib tug thickener yog ua kom lub viscosity ntawm cov kua xab npum los ntawm dissolving nyob rau hauv dej los tsim ib tug viscos kua. Tshwj xeeb, thaum HEC yog yaj hauv dej, nws cov saw hlau molecular ua ke nrog cov dej molecules los ntawm cov ntawv cog lus hydrogen intermolecular los tsim cov qauv sib txuas. Cov qauv network no tuaj yeem khi ntau cov dej molecules zoo, yog li ua kom cov viscosity ntawm cov tshuaj.
Cov nyhuv thickening ntawm HEC yog ze ze rau nws qhov hnyav molecular thiab tus nqi ntxiv. Feem ntau hais lus, ntau dua qhov hnyav molecular ntawm HEC, qhov siab dua qhov viscosity ntawm cov tshuaj tsim; Nyob rau tib lub sijhawm, qhov siab dua qhov siab ntawm HEC hauv cov tshuaj, qhov pom tseeb dua cov nyhuv thickening yuav yog. Txawm li cas los xij, hauv kev siv tswv yim, HEC siab ntau dhau tuaj yeem ua rau cov tshuaj muaj kuab heev thiab cuam tshuam rau cov neeg siv kev paub, yog li nws yuav tsum tau ua tib zoo tswj thaum lub sij hawm tsim.
3. Qhov zoo ntawm HEC thickening nyhuv
HEC muaj ntau yam zoo dua lwm cov thickeners. Ua ntej tshaj plaws, nws muaj dej solubility zoo heev thiab tuaj yeem yaj sai sai hauv dej txias lossis dej kub thiab tsim cov kua dej tsis sib xws. Qhov thib ob, HEC tsis tsuas yog thickens zoo ntawm qhov qis dua, tab sis kuj muab cov nyhuv thickening ruaj khov, uas yog qhov tseem ceeb tshwj xeeb hauv cov khoom siv xab npum uas yuav tsum tau khaws cia ntev. Thib peb, raws li cov tsis-ionic thickener, HEC tuaj yeem tswj cov viscosity ruaj khov nyob rau hauv cov pH sib txawv thiab tsis yooj yim cuam tshuam los ntawm lwm cov khoom hauv lub cev.
4. Kev siv HEC hauv kev tsim cov kua xab npum
Hauv kev tsim khoom tiag tiag, HEC feem ntau yog ntxiv rau cov kua xab npum formulations hauv hmoov. Txhawm rau kom ntseeg tau tias HEC tuaj yeem yaj tag nrho thiab ua kom nws cov nyhuv thickening, feem ntau nws yog ib qho tsim nyog yuav tsum tau ua tib zoo saib xyuas qhov sib xyaw ntawm kev sib xyaw thaum ntxiv HEC kom tsis txhob muaj agglomeration. Tsis tas li ntawd, txhawm rau txhawm rau txhim kho kev ua tau zoo ntawm cov kua xab npum, HEC feem ntau siv nrog rau lwm cov thickeners, humectants lossis surfactants kom ua tiav cov khoom zoo nkauj thiab cov neeg siv kev paub.
Raws li cov thickener muaj txiaj ntsig, hydroxyethyl cellulose muaj cov ntawv thov dav dav hauv cov kua xab npum. Nws tuaj yeem ua rau kom muaj viscosity ntawm cov khoom thiab txhim kho cov neeg siv kev paub. Nws kuj muaj kev sib raug zoo thiab ruaj khov thiab yog qhov kev xaiv zoo tshaj plaws rau cov kua xab npum thickening.
Post lub sij hawm: Aug-19-2024