Qhov zoo ntawm Pharmaceutical Qib HPMC

HPMC tau dhau los ua ib qho ntawm cov khoom siv tshuaj ntau tshaj plaws hauv tsev thiab txawv teb chaws, vim tias HPMC muaj qhov zoo uas lwm cov excipients tsis muaj.

1. Dej solubility

Soluble hauv dej txias hauv qab 40 ° C lossis 70% ethanol, feem ntau insoluble hauv dej kub siab tshaj 60 ° C, tab sis tuaj yeem gel.

2. Tshuaj inertness

HPMC yog ib yam uas tsis yog-ioniccellulose ether. Nws cov tshuaj tsis muaj ionic nqi thiab tsis cuam tshuam nrog hlau ntsev los yog ionic organic tebchaw. Yog li ntawd, lwm cov excipients tsis hnov ​​​​mob nrog nws thaum lub sijhawm npaj.

3. Kev ruaj ntseg

Nws yog qhov ruaj khov rau cov kua qaub thiab alkali, thiab tuaj yeem khaws cia rau lub sijhawm ntev ntawm pH 3 thiab 11 yam tsis muaj kev hloov pauv hauv viscosity. Cov tshuaj aqueous ntawm HPMC muaj cov nyhuv anti-mildew thiab tuaj yeem tswj cov viscosity ruaj khov thaum lub sij hawm ntev cia. Kev ruaj ntseg zoo ntawm cov tshuaj siv HPMC raws li kev npaj excipients yog zoo dua li cov tshuaj uas siv cov tshuaj ib txwm siv (xws li dextrin, starch, thiab lwm yam).

4. Adjustable viscosity

Qhov sib txawv viscosity derivatives ntawm HPMC tuaj yeem sib xyaw ua ke raws li qhov sib txawv, thiab nws cov viscosity tuaj yeem hloov pauv raws li qee txoj cai, thiab muaj kev sib raug zoo linear, yog li qhov sib piv tuaj yeem xaiv raws li qhov xav tau. 2.5 Metabolism inert HPMC tsis absorbed los yog metabolized nyob rau hauv lub cev, thiab tsis muab cua sov, yog li nws yog ib tug muaj kev ruaj ntseg tshuaj npaj excipient. .

5. Kev ruaj ntseg

HPMC feem ntau suav hais tias yog cov khoom tsis muaj tshuaj lom thiab tsis ua rau khaus.