He aha ka ʻokoʻa ma waena o ka methylcellulose a me ka hydroxypropylmethylcellulose?

ʻO ka methyl cellulose (MC) a me ka hydroxypropyl methyl cellulose (HPMC) ʻelua mau mea hoʻohana i hoʻohana nui ʻia i ka ʻoihana, ke kūkulu hale, nā lāʻau lapaʻau, nā meaʻai a me nā māla ʻē aʻe. ʻOiai ua like lākou i ka hoʻolālā, loaʻa iā lākou nā waiwai like ʻole a Aia nā ʻokoʻa nui i nā noi a me nā kaʻina hana.

1. Nā ʻokoʻa o ka hana kemika

ʻO ka Methylcellulose (MC) a me ka hydroxypropylmethylcellulose (HPMC) nā mea ʻelua i loaʻa mai ka cellulose maoli a ua hoʻololi kemika i nā pūhui cellulose ether. Akā ʻo kā lākou ʻokoʻa e pili ana i ke ʻano a me ka helu o nā pūʻulu substituent.

Methyl cellulose (MC)
Hana ʻia ka MC ma ka hoʻololi ʻana i nā pūʻulu hydroxyl ma cellulose me nā pūʻulu methyl (ie -OCH₃). ʻO ka hoʻolālā kemika o MC ka nui o nā pūʻulu methyl substituent ma ke kaulahao nui cellulose, a ʻo kona wikiwiki hoʻololi e pili ana i kona solubility a me nā waiwai. Hiki ke hoʻoheheʻe ʻia ka MC i ka wai anuanu akā ʻaʻole i ka wai wela.

Hydroxypropyl methylcellulose (HPMC)
Hoʻololi hou ʻia ka HPMC ma ke kumu o ka methylcellulose, ma ka hoʻololi ʻana i kahi hapa o nā hui hydroxyl me ka methyl (-CH₃) a me ka hydroxypropyl (-CH₂CH(OH)CH₃). Ke hoʻohālikelike ʻia me MC, ʻoi aku ka paʻakikī o ka molecular structure o HPMC, ʻoi aku ka maikaʻi o kona hydrophilicity a me ka hydrophobicity, a hiki ke hoʻoheheʻe ʻia i ka wai anuanu a me ka wai wela.

2. ʻOkoʻa o ke kino a me ka hoʻoheheʻe waiwai

MC: Methylcellulose maʻamau ka hiki ke hoʻoheheʻe maikaʻi ʻia i ka wai anuanu, akā e hana ʻia i gel ke piʻi ka mahana. I loko o ka wai wela, lilo ka MC i insoluble, e hana ana i kahi gel wela.
HPMC: Hiki ke hoʻoheheʻe ʻia ka Hydroxypropyl methylcellulose i loko o ke anuanu a me ka wai wela, loaʻa kahi ākea ākea ākea, a ʻoi aku ka paʻa o kona solubility ma mua o MC.

ʻO ka hoʻoheheʻe wela
MC: Loaʻa i ka MC nā waiwai gelling thermal. Ke piʻi ka mahana i kahi pae, e hana ia i gel a nalowale kona solubility. ʻO kēia hiʻohiʻona e loaʻa iā ia nā hoʻohana kūikawā i ka hana kūkulu a me nā ʻoihana lāʻau.
HPMC: Loaʻa i ka HPMC kekahi mau waiwai hoʻoheheʻe wela, akā ʻoi aku ka kiʻekiʻe o ka hoʻokumu ʻana o ka gel a ʻoi aku ka lohi o ka hana gel. Hoʻohālikelike ʻia me MC, ʻoi aku ka maʻalahi o nā waiwai gel thermal o HPMC a no laila ʻoi aku ka maikaʻi i nā noi e koi ana i ke kūpaʻa wela kiʻekiʻe.

Hana i luna
MC: He haʻahaʻa ko MC. ʻOiai hiki ke hoʻohana ʻia ma ke ʻano he emulsifier a mānoanoa paha i kekahi mau noi, ʻaʻole nui ka hopena e like me HPMC.
HPMC: He ʻoi aku ka ikaika o ka HPMC ma luna o ka ʻili, ʻoi aku ka hoʻokomo ʻana o ka hui hydroxypropyl, kahi e maʻalahi ai ka emulsify, hoʻokuʻu a mānoanoa i ka hopena. No laila, hoʻohana nui ʻia e like me ka mea hoʻohui i nā mea uhi a me nā mea kūkulu hale.

ʻO ka paʻakai paʻakai a me ka paʻa pH
MC: ʻAʻole ʻae ʻia ka paʻakai ʻo Methylcellulose a hiki i ka ua ma nā wahi paʻakai kiʻekiʻe. Loaʻa ka paʻa maikaʻi ʻole i ka ʻakika a me ka alkali a hiki ke hoʻopili ʻia e ka waiwai pH.
HPMC: Ma muli o ka loaʻa ʻana o ka hydroxypropyl substituent, ʻoi aku ka maikaʻi o ka hoʻomanawanui paʻakai o HPMC ma mua o MC, a hiki iā ia ke mālama i ka solubility maikaʻi a me ka paʻa i kahi ākea pH ākea, no laila ua kūpono ia no nā ʻano kemika like ʻole.

3. Nāʻokoʻa i nā hana hana

Hana ʻia o MC
Hana ʻia ka Methylcellulose ma o ka hopena methylation o ka cellulose, me ka hoʻohana maʻamau i ka methyl chloride e hana me ka cellulose alkaline e pani i nā pūʻulu hydroxyl i loko o nā molekole cellulose. Pono kēia kaʻina hana i ka hoʻomalu ʻana i nā kūlana pane e hōʻoia i ka pae kūpono o ka hoʻololi ʻana, e pili ana i ka solubility a me nā waiwai physicochemical ʻē aʻe o ka huahana hope.

Hana ʻia o HPMC
Hoʻokumu ʻia ka hana ʻana o HPMC ma ka methylation a hoʻohui i ka hopena hydroxypropylation. ʻO ia hoʻi, ma hope o ka hopena methylation o ka methyl chloride, hana ka propylene oxide me ka cellulose e hana i kahi mea pani hydroxypropyl. ʻO ka hoʻokomo ʻana o ka pūʻulu hydroxypropyl e hoʻomaikaʻi i ka solubility a me ka hydration hiki o HPMC, ʻo ia hoʻi ka mea e hana ai i kāna kaʻina hana i ʻoi aku ka paʻakikī a ʻoi aku ka nui o ke kumukūʻai ma mua o MC.

4. Nā ʻokoʻa ma nā kahua noi

kahua lako hale
MC: Hoʻohana pinepine ʻia ʻo MC i nā mea kūkulu hale, ʻoi aku ka mānoanoa, ka mea hoʻopaʻa wai a me ka hoʻopili ʻana i ka moka maloʻo a me ka pauka putty. Eia nō naʻe, ma muli o kāna mau waiwai gelling thermal, hiki i ka MC ke hāʻule i nā wahi wela kiʻekiʻe.
HPMC: Hoʻohana nui ʻia ka HPMC ma ke kahua kūkulu. No ka mea, he kūpaʻa maikaʻi nō hoʻi i nā wahi wela kiʻekiʻe, ʻoi aku ka maikaʻi o nā hiʻohiʻona e koi ai i ka hoʻomanawanui ʻana o ka mahana, e like me nā tile adhesives, insulation mortars a me nā papahele hoʻonaʻauao ponoʻī. .

Nā māla lāʻau a me nā meaʻai
MC: Hoʻohana mau ʻia ka Methylcellulose ma ke ʻano he disintegrant a me ka mānoanoa no nā papa i loko o ka hoʻomākaukau lāʻau. Hoʻohana ʻia ia i kekahi mau meaʻai ma ke ʻano he mānoanoa a me ka fiber supplement.
HPMC: He ʻoi aku ka maikaʻi o ka HPMC ma ke kahua lāʻau lapaʻau. Ma muli o kona paʻa paʻa a me ka biocompatibility maikaʻi, hoʻohana pinepine ʻia i nā mea kiʻiʻoniʻoni hoʻokuʻu mau a me nā pūpū capsule no nā lāʻau lapaʻau. Eia kekahi, hoʻohana nui ʻia ka HPMC i ka ʻoihana meaʻai, ʻoi aku hoʻi i ka hana ʻana i nā capsules vegetarian.

ʻĀpana uhi a pena
MC: Ua ʻoi aku ka maikaʻi o ka mānoanoa a me nā hopena hana kiʻiʻoniʻoni, akā ʻaʻole maikaʻi kona kūpaʻa a me ka hiki ke hoʻoponopono viscosity i ka hopena e like me HPMC.
HPMC: Hoʻohana nui ʻia ʻo HPMC i ka pena a me ka ʻoihana pena ma muli o kona mānoanoa maikaʻi loa, emulsification a me nā waiwai hana kiʻiʻoniʻoni, ʻoi aku hoʻi ma ke ʻano he mānoanoa a me ka pae hoʻohālikelike i nā uhi wai, hiki ke hoʻomaikaʻi nui i ka hana hana a me ka ʻili o ka uhi. . Ka hopena.

5. Ka palekana a me ka palekana

Hoʻololi ʻia ʻo MC a me HPMC mai ka cellulose kūlohelohe a loaʻa iā lākou ka biodegradability maikaʻi a me nā waiwai palekana kaiapuni. ʻAʻohe mea ʻawaʻawa a maikaʻi ʻole i ka hoʻohana ʻana a hoʻokō i nā koi palekana o ke kaiapuni, no laila palekana loa lākou e hoʻohana ʻia ma nā ʻano meaʻai, nā lāʻau lapaʻau a me nā mea hoʻonaninani.

ʻOiai ua like ka methylcellulose (MC) a me ka hydroxypropylmethylcellulose (HPMC) i ka hoʻolālā kemika, ma muli o nā hui substituent ʻokoʻa, ʻokoʻa ko lākou solubility, thermal gelability, surface activity, production process and application. Aia nā ʻokoʻa ʻokoʻa ma nā māla a me nā ʻano ʻē aʻe. Ua kūpono ʻo MC no nā wahi haʻahaʻa haʻahaʻa a me ka maʻalahi o ka mānoanoa a me ka mālama ʻana i ka wai, ʻoiai ʻoi aku ka maikaʻi o ka HPMC no nā ʻoihana paʻakikī, lāʻau lapaʻau a me nā noi kūkulu hale ma muli o kona solubility maikaʻi a me ka paʻa wela.