Ka palekana o CMC

ʻO ka sodium carboxymethyl cellulose (CMC) ka mea maʻamau i manaʻo ʻia he palekana (GRAS) no ka ʻai ʻana e nā luna hoʻoponopono e like me ka Food and Drug Administration (FDA) ma United States a me ka European Food Safety Authority (EFSA) ma ʻEulopa ke hoʻohana ʻia e like me ka maikaʻi. nā hana hana (GMP) a me nā kulekele palekana i hoʻokumu ʻia. Eia kahi hiʻohiʻona o nā noʻonoʻo palekana e pili ana me CMC:

1. ʻApono hoʻoponopono: Ua ʻae ʻia ʻo CMC no ka hoʻohana ʻana i mea hoʻohui meaʻai ma nā ʻāina he nui o ka honua, me ʻAmelika Hui Pū ʻIa, ʻEulopa, Kanada, Australia, a me Iapana. Hoʻopaʻa inoa ʻia me nā keʻena hoʻoponopono like ʻole he mea hoʻohui meaʻai i ʻae ʻia me nā palena hoʻohana kikoʻī a me nā kikoʻī.
2. Nā haʻawina ʻona: Ua mālama ʻia nā haʻawina toxicological nui e loiloi i ka palekana o CMC no ka ʻai kanaka. ʻO kēia mau haʻawina e pili ana i nā hoʻāʻo ʻawaʻawa acute, subchronic, a me ka mauʻu, a me ka mutagenicity, genotoxicity, a me nā loiloi carcinogenicity. Ma muli o ka ʻikepili i loaʻa, manaʻo ʻia ʻo CMC he palekana no ka ʻai kanaka ma nā pae i ʻae ʻia.
3. ʻAe ʻia ka lawe ʻana i kēlā me kēia lā (ADI): Ua hoʻokumu nā keʻena hoʻoponopono i nā waiwai kūpono i kēlā me kēia lā (ADI) no CMC ma muli o nā haʻawina toxicological a me nā loiloi palekana. Hōʻike ka ADI i ka nui o ka CMC hiki ke hoʻopau ʻia i kēlā me kēia lā i ke ola me ka ʻole o ka pilikia i ke olakino. ʻOkoʻa nā koina ADI ma waena o nā keʻena hoʻoponopono a hōʻike ʻia ma nā huaʻōlelo o ka milligrams no ke kilokani o ke kaumaha o ke kino i kēlā me kēia lā (mg/kg bw/lā).
4. Allergenicity: Loaʻa ka CMC mai ka cellulose, kahi polysaccharide kūlohelohe i loaʻa i loko o nā paia o nā mea kanu. ʻAʻole ʻike ʻia ke kumu o ka maʻi maʻi i ka lehulehu. Eia nō naʻe, ʻo ka poʻe me nā maʻi allergies i ʻike ʻia a i ʻole nā ​​​​maʻi i ka cellulose derivatives e hana makaʻala a nīnau i nā limahana mālama ola ma mua o ka ʻai ʻana i nā huahana me ka CMC.
5. Palekana Digestive: ʻAʻole komo ʻia ka CMC e ka ʻōnaehana hoʻoheheʻe kanaka a hele i ka ʻōpū o ka ʻōpū me ka ʻole o ka metabolized. Manaʻo ʻia ʻaʻole ia he mea ʻawaʻawa a ʻaʻole hoʻonāukiuki i ka mucosa digestive. Eia nō naʻe, ʻo ka hoʻohana nui ʻana i ka CMC a i ʻole nā ​​​​mea hoʻoheheʻe cellulose ʻē aʻe e hiki ke hōʻeha i ka ʻōpū o ka ʻōpū, bloating, a i ʻole ka maʻi maʻi i kekahi poʻe.
6. Ka launa pū me nā lāʻau lapaʻau: ʻAʻole ʻike ʻia ʻo CMC e launa pū me nā lāʻau lapaʻau a i ʻole e pili ana i kā lākou absorption i loko o ka ʻōpū o ka ʻōpū. Manaʻo ʻia ʻo ia ka mea kūpono me ka hapa nui o nā ʻano lāʻau lapaʻau a hoʻohana maʻamau ʻia ma ke ʻano he excipient i nā ʻano o ka waha e like me nā papa, nā capsules, a me nā hoʻokuʻu.
7. Palekana Kaiapuni: He biodegradable ka CMC a me ke kaiapuni, no ka mea, ua loaʻa ia mai nā kumu hou e like me ka pulp lāʻau a i ʻole ka pulupulu cellulose. Ua wāwahi maoli ia i loko o ke kaiapuni ma o ka hana microbial a ʻaʻole e hōʻiliʻili i loko o ka lepo a i ʻole nā ​​ʻōnaehana wai.

I ka hōʻuluʻulu ʻana, manaʻo ʻia ka sodium carboxymethyl cellulose (CMC) i palekana no ka ʻai ʻana ke hoʻohana ʻia e like me nā alakaʻi hoʻoponopono a me nā kūlana palekana. Ua aʻo nui ʻia no kona ʻona, ka allergenicity, ka palekana digestive, a me ka hopena o ke kaiapuni, a ua ʻae ʻia no ka hoʻohana ʻana ma ke ʻano he meaʻai meaʻai a me ka lāʻau lapaʻau i nā ʻāina he nui o ka honua. E like me nā meaʻai a i ʻole nā ​​mea hoʻohui, pono nā kānaka e ʻai i nā huahana me ka CMC me ka maʻalahi ma ke ʻano he ʻāpana o ka meaʻai kaulike a nīnau i nā limahana mālama ola inā loaʻa iā lākou nā mea ʻai a i ʻole nā ​​pilikia olakino.