ʻO ka Hydroxypropyl methylcellulose HPMC he mea non-ionic cellulose i hui pū ʻia ma waena o nā ʻano eter i hui pū ʻia me ka ionic methylcarboxymethylcellulose. ʻAʻole ia e pane me nā metala kaumaha. ʻO nā ʻokoʻa o ka maʻiʻo o ka hydroxypropyl methylcellulose, hydroxypropyl methylcellulose, a me ka ratio hydroxypropyl content ratio a me ka viscosity o ka gene free oxygen he mau ʻano like ʻole ma ke ʻano o ka hana. No ka laʻana, ʻokoʻa ka hana o nā ʻano me ka methoxyl kiʻekiʻe a me ka haʻahaʻa hydroxypropyl. Kokoke i ka methylcellulose a me nā ʻano methoxy haʻahaʻa. Ke hoʻohālikelike ʻia me nā ʻano like me ka hydroxypropyl content kiʻekiʻe, ua kokoke kāna hana i ka hydroxypropyl methylcellulose i hana ʻia. Eia nō naʻe, ʻoiai he liʻiliʻi wale nō ka pūʻulu hydroxypropyl i kēlā me kēia ʻano like ʻole a i ʻole ka pūʻulu methoxy liʻiliʻi, aia nā ʻokoʻa nui i ka solubility i nā mea hoʻoheheʻe organik a i ʻole ka wela o ka flocculation i loko o nā haʻina wai.
1. Ka hoʻoheheʻe ʻia o ka hydroxypropyl methylcellulose
Hiki i ka hydroxypropyl methylcellulose i loko o ka wai ʻO ka hydroxypropyl methylcellulose he propylene oxide (methylhydroxypropyl ring) i hoʻololi ʻia i ka methylcellulose, no laila he mau waiwai like kona me ka methylcellulose He mau waiwai like kona hiki ke hoʻoheheʻe ʻia i ka wai anuanu akā hiki ʻole ke hoʻoheheʻe ʻia i ka wai wela. Eia naʻe, ʻoi aku ka kiʻekiʻe o ka mahana gelling o ka hydroxypropyl i hoʻololi ʻia i ka wai wela ma mua o ka methylcellulose. No ka laʻana, he 2% hydroxypropyl methylcellulose aqueous solution me ka methoxy group content DS=0.73 a me ka hydroxypropyl group content MS=0.46 he viscosity o 500mpa ma 20°C. ʻO ka mahana gel o ka huahana S kokoke i 100 ° C, ʻoiai ʻo ka methylcellulose i ka mahana like ma kahi o 55 ° C wale nō. No kona hikiwawe i ka wai, ua hoʻomaikaʻi nui ʻia. No ka laʻana, ma hope o ka hydroxypropyl methylcellulose e paʻi ʻia (ʻo 0.2 ~ 0.5mm ke kinona, ʻo ka viscosity o 4% wai ma 20 ° C he 2pA · S, hiki ke hoʻohana ʻia ma ka lumi wela me ka ʻole o ka hoʻoheheʻe.
(2) ʻO ka solubility o ka hydroxypropyl methylcellulose i loko o nā mea hoʻoheheʻe ʻia ʻO ka solubility o ka hydroxypropyl methylcellulose i loko o nā mea hoʻoheheʻe ʻia ʻoi aku ka maikaʻi ma mua o ka methylcellulose. Pono ka Methylcellulose i kahi degere hoʻololi methoxy o 2.1 ʻO nā huahana ma luna nei he hydroxypropyl methylcellulose kiʻekiʻe-viscosity me ka hydroxypropyl MS = 1.5 ~ 1.8 a me ka methoxy DS = 0.2 ~ 1.0, me kahi degere hoʻololi holoʻokoʻa ʻoi aku ma mua o 1.8, a ua maʻalahi hoʻi i ka methanol anhydrous. ethanol solutions. Thermoplastic a me ka wai-soluble. Hiki ke hoʻoheheʻe ʻia i nā hydrocarbons chlorinated e like me ka methylene chloride a me ka chloroform, a me nā mea hoʻoheheʻe kūlohelohe e like me ka acetone, isopropyl alcohol a me ka diacetone alcohol. ʻOi aku ka maikaʻi o kona hoʻoheheʻe ʻana i nā mea hoʻoheheʻe organik ma mua o ka hoʻoheheʻe wai.
2. Nā mea e pili ana i ka viscosity o ka hydroxypropyl methylcellulose
Hydroxypropyl methylcellulose viscosity factor ʻO ke ana viscosity maʻamau o ka hydroxypropyl methylcellulose ua like ia me nā cellulose ethers ʻē aʻe, a ua ana ʻia ma 20 ° C me ka 2% aqueous solution ma ke ʻano maʻamau. Piʻi ka viscosity o ka huahana like me ka piʻi ʻana o ka ʻike. No nā huahana me ka manaʻo like a me nā paona molekala like ʻole, ʻoi aku ka nui o ka viscosity o ka huahana me ke kaumaha molekala nui. Ua like kona pilina me ka wela me ka methylcellulose. Ke piʻi ka mahana, hoʻomaka ka viscosity e emi, akā i ka hiki ʻana i kahi mahana, piʻi koke ka viscosity a puka ka gelation. Loaʻa i nā huahana viscosity haʻahaʻa ka wela gelling kiʻekiʻe ma mua o nā huahana viscosity kiʻekiʻe. ʻAʻole pili wale ka helu gel i ka viscosity o ka ether, akā pili pū kekahi i ka ratio haku mele o nā hui methoxy a me hydroxypropyl i loko o ka ether a me ka huina o ka hoʻololi. Pono e hoʻomaopopo ʻia he pseudoplastic pū kekahi hydroxypropyl methylcellulose; paʻa kona mau haʻina ke mālama ʻia ma ka lumi wela a ʻaʻole hōʻike i ka emi ʻana o ka viscosity, koe wale nō ka hiki ke hoʻohaʻahaʻa i ka enzymatic.
3. ʻO ka hydroxypropyl methylcellulose ka waikawa a me ka alkali
ʻO ka Hydroxypropyl methylcellulose ka waikawa a me ka alkali. ʻO ka Hydroxypropyl methyl cellulose ka waikawa a me ka alkali. Paʻa maʻamau a ʻaʻole e hoʻopilikia ʻia e ka waiwai pH ma ka laulā o PH2 ~ 12. Hiki iā ia ke pale i kekahi nui o nā ʻakika nāwaliwali, e like me ka formic acid, acetic acid, a me ka lemon. ʻO kaʻakika, kaʻakika succinic, ka waikawa phosphoric akāʻo kaʻakika concentrated ka hopena o ka ho'ēmiʻana i ka viscosity. ʻAʻohe hopena o ka alkali e like me ka soda caustic, caustic potassium, a me ka wai lime, akā e emi iki ka hopena o ka hoʻonui iki ʻana i ka viscosity o ka hopena.
4. Hiki ke hui 'ia ka Hydroxypropyl methylcellulose
Hiki ke hoʻohui ʻia ka solution hydroxypropyl methylcellulose me nā pūhui polymer hiki ke hoʻoheheʻe ʻia i ka wai e hana i kahi ʻano like ʻole a me ka ʻākala me ka viscosity kiʻekiʻe. ʻO kēia mau pūhui polymer ka polyethylene glycol, polyvinyl acetate, polysiloxane, polymethyl vinyl siloxane, hydroxyethyl cellulose a me methyl cellulose. ʻO nā pūhui polimer kūlohelohe e like me ka ʻākacia gum, ka ʻūhini pī, ka ʻūhini, a me nā mea ʻē aʻe he maikaʻi ka hui ʻana. kona hopena. Hiki ke hui pū ʻia ka Hydroxypropyl methylcellulose me ka waikawa stearic a i ʻole mannitol palmitate a i ʻole sorbitol, a hiki ke hui pū ʻia me ka glycerin, sorbitol a me ka mannitol. Hiki ke hoʻohana ʻia kēia mau pūhui e like me ka hydroxypropyl methylcellulose plasticizers agent.
5. ʻAʻole hiki ke hoʻoheheʻe ʻia ka Hydroxypropyl methylcellulose i ka wai
ʻAʻole hiki ke hoʻoheheʻe ʻia ka Hydroxypropyl methylcellulose i loko o nā etera cellulose hiki ke hoʻopili ʻia me nā aldehydes, e hoʻoheheʻe ʻia kēia mau eter hiki ke hoʻoheheʻe ʻia i ka wai. A hana i ka hydroxypropyl methylcellulose insoluble i loko o nā aldehydes, formaldehyde, glyoxal, succinic acid, dialdehyde, etc. I ka hoʻohana ʻana i ka formaldehyde, pono e uku nui ʻia i ka waiwai pH o ka hopena. Ma waena o lākou, hoʻololi koke ka glyoxal, no laila hoʻohana ʻia ia i ka ʻoihana Hoʻohana maʻamau ʻo Glyoxal ma ke ʻano he mea hoʻopili cross-linking i ka hana. - Agena hoʻopili. ʻO ke ʻano o kēia ʻano o ka mea hoʻohui cross-link i ka hopena he 0.2% a 10% o ka nui o ka ether, a ʻo ka mea maikaʻi loa ʻo 7% a 10%. Inā hoʻohana ʻia ka glyoxal, 3.3% a 6% ka mea kūpono loa. ʻO ka mahana mālama maʻamau he 0 ~ 30 ℃ a ʻo ka manawa he 1 ~ 120min. Pono e hoʻokō ʻia ka hopena hoʻopili keʻa ma lalo o nā kūlana acidic. ʻO ka maʻamau, hoʻohui ʻia ka ʻakika ikaika inorganic a i ʻole ka waikawa carboxylic organik i ka hoʻonā e hoʻoponopono i ka pH o ka hopena i kahi 2 a i 6, ʻoi aku ka maikaʻi ma waena o 4 a me 6, a laila hoʻohui ʻia nā aldehydes e hana i ka hopena hoʻohui kea. ʻO nā ʻakika i hoʻohana ʻia he waika hydrochloric, sulfuric acid, phosphoric acid, formic acid, acetic acid, glycolic acid, succinic acid a i ʻole citric acid, ma waena o ka waika formic a i ʻole acetic acid ka mea maikaʻi loa, a ʻo ka formic acid ka mea maikaʻi loa. Hiki ke hoʻohui ʻia nā ʻakika a me nā aldehydes i ka manawa like e hoʻopili i ka hopena i loko o ka pae pH makemake ʻia. Hoʻohana pinepine ʻia kēia hopena i ka hana hope o ke kaʻina hoʻomākaukau cellulose ether e hana i ka cellulose ether insoluble a maʻalahi i ka holoi ʻana a me ka hoʻomaʻemaʻe ʻana me ka wai 20 ~ 25 ° C. I ka hoʻohana ʻana i ka huahana, hiki iā ʻoe ke hoʻohui i nā mea alkaline i ka hopena huahana e hoʻoponopono i ka pH o ka hopena i alkaline i hiki ai i ka huahana ke hoʻoheheʻe koke i ka hopena. Hiki ke hoʻohana ʻia kēia ʻano hana i ka wā i hoʻomākaukau ʻia ai kahi kiʻiʻoniʻoni me ka hoʻohana ʻana i ka cellulose ether solution a laila e hana ʻia ke kiʻiʻoniʻoni i loko o kahi kiʻiʻoniʻoni insoluble.
6. Hydroxypropyl methylcellulose anti-enzyme
ʻO nā derivatives cellulose o ka hydroxypropyl methylcellulose ka mea kūʻē i nā enzymes. No ka laʻana, ua hoʻopaʻa paʻa ʻia kēlā me kēia hui anhydroglucose me kahi pūʻulu pani a ʻaʻole hiki ke maʻalahi i ka microbial erosion a me ka maʻi. Eia naʻe, ʻoiaʻiʻo, ʻoi aku ka nui o ke kumukūʻai o ka huahana i hoʻopau ʻia ma mua o 1. Hiki ke hoʻohaʻahaʻa ʻia e nā enzymes, e hōʻike ana i ke ʻano o ka hoʻololi ʻana o kēlā me kēia hui i ke kaulahao cellulose ʻaʻole kūlike, a hiki i nā microorganisms ke hoʻopau i nā pūʻulu anhydroglucose kokoke i hoʻololi ʻole ʻia. ke kō, hiki ke hoʻomoʻa ʻia e nā microorganism i meaʻai. No laila, inā piʻi ke degere o ka hoʻololi ʻana i ka ether o cellulose, e piʻi ke kūʻē o nā eter cellulose i ka hoʻouka ʻana i ka enzymatic. Ua hōʻike ʻia ma lalo o nā kūlana i hoʻomalu ʻia, hydroxypropyl methylcellulose (DS=1.9), methylcellulose (DS=1.83), methylcellulose (DS=1.66), hydroxyethylcellulose (1.7%) ʻO nā viscosities koena he 13.2%, 7.3%, 3.8% a me 1.7% pakahi. Loaʻa i ka Hydroxypropyl methylcellulose nā mana anti-enzyme ikaika. Hiki ke ʻike ʻia ʻo ka hydroxypropyl methylcellulose he kūpaʻa enzyme maikaʻi loa, hui pū ʻia me kāna dispersion maikaʻi, mānoanoa a me nā waiwai hana kiʻiʻoniʻoni, hiki ke hoʻohana ʻia i nā emulsion coatings, etc., a ʻaʻole pono e hoʻohui i nā preservatives. Eia nō naʻe, i mea e pale ai i ka hopena mai ka mālama ʻana i ka wā lōʻihi a i ʻole ka hoʻohaumia ʻana i waho, hiki ke hoʻohui ʻia nā preservatives, a hiki ke hoʻoholo ʻia ke koho ʻana o nā mea mālama ma muli o nā koi hope o ka hopena. ʻO ka Phenylmercuric acetate a me ka manganese fluorosilicate nā mea mālama pono, akā he mea ʻawaʻawa lākou a pono e mālama ʻia me ka mālama. ʻO ka maʻamau, hiki ke hoʻohui ʻia ka 1 a 5 mg o ka phenylmercuric acetate i kēlā me kēia lita o ka hopena.
7. Ka hana o ka membrane hydroxypropyl methylcellulose
ʻO Hydroxypropyl methylcellulose nā waiwai hana kiʻiʻoniʻoni ʻO ka Hydroxypropyl methylcellulose he mau waiwai hana kiʻiʻoniʻoni maikaʻi loa. Ke uhi ʻia kāna ʻano wai a i ʻole nā mea hoʻoheheʻe organik ma luna o kahi pā aniani, lilo ia i kiʻi ʻoniʻoni ʻole, ʻikea a paʻakikī ma hope o ka maloʻo ʻana. . He kūpaʻa maikaʻi kona maʻamau a paʻa mau i nā wela kiʻekiʻe. Inā hoʻohui ʻia nā plasticizers hygroscopic, hiki ke hoʻonui ʻia ka elongation a me ka maʻalahi, a hiki ke hoʻomaikaʻi ʻia ka maʻalahi. ʻO nā plasticizers e like me ka glycerol a me ka sorbitol ka mea kūpono loa. ʻO ka hoʻonā hopena maʻamau he 2% ~ 3%, a ʻo ka plasticizer dosage he 10% ~ 20% o ka cellulose ether. Inā kiʻekiʻe ka ʻike o ka plasticizer, e kū mai ka syneresis colloid ma lalo o ka haʻahaʻa kiʻekiʻe. ʻOi aku ka ikaika o ka tensile o ka kiʻiʻoniʻoni me ka plasticizer i hoʻohui ʻia ma mua o ka kiʻiʻoniʻoni me ka ʻole o ka plasticizer, a hoʻonui ia me ka nui o ka plasticizer i hoʻohui ʻia. Hoʻonui pū ka hygroscopicity o ke kiʻi me ka nui o ka plasticizer.
Ka manawa hoʻouna: Feb-01-2024