ʻO ka Hydroxypropyl methylcellulose (HPMC) he mea hoʻohui wai-soluble polymer i hoʻohana nui ʻia i ka lāʻau lapaʻau, ka meaʻai, nā mea kūkulu hale a me nā māla ʻē aʻe. Ma muli o kona mānoanoa maikaʻi, hana kiʻiʻoniʻoni, emulsifying, hoʻopaʻa ʻana a me nā waiwai ʻē aʻe, hoʻohana nui ʻia ʻo ia ma ke ʻano he mānoanoa, stabilizer a me ka suspending agent. ʻO nā waiwai rheological o HPMC, ʻoi aku ka nui o kāna hana ʻana i nā mahana like ʻole, he mau mea nui e pili ana i kāna hopena noi.
1. Ka Manawa o HPMC Rheological Properties
ʻO nā waiwai Rheological kahi hōʻike piha o ka deformation a me nā hiʻohiʻona kahe o nā mea ma lalo o nā mana o waho. No nā mea polymer, ʻo ka viscosity a me ka shear thinning behavior nā ʻāpana rheological maʻamau ʻelua. Hoʻopili nui ʻia nā waiwai rheological o HPMC e nā mea e like me ke kaumaha molekala, ka ʻike, nā waiwai solvent a me ka mahana. E like me ka non-ionic cellulose ether, HPMC hōʻike pseudoplasticity i aqueous solution, ʻo ia hoʻi, e emi ana kona viscosity me ka piʻi ʻana o ka shear rate.
2. Ka hopena o ka Mahana ma HPMC Viscosity
ʻO ka mahana kekahi o nā kumu nui e pili ana i nā waiwai rheological o HPMC. Ke piʻi aʻe ka mahana, e emi mau ana ka viscosity o ka solution HPMC. ʻO kēia ke kumu o ka hoʻonui ʻana i ka mahana e hoʻonāwaliwali i ka pilina paʻa hydrogen ma waena o nā molekele wai, a laila e hōʻemi ana i ka ikaika o ka pilina ma waena o nā kaulahao molekala HPMC, e maʻalahi ai ka paheʻe ʻana o nā kaulahao molekala. No laila, i nā mahana kiʻekiʻe, hōʻike nā ʻōnaehana HPMC i ka viscosity haʻahaʻa.
Eia naʻe, ʻaʻole pili laina ka hoʻololi viscosity o HPMC. Ke piʻi ka mahana i kekahi ʻano, hiki i ka HPMC ke hana i kahi kaʻina hoʻoheheʻe-ua. No HPMC, ʻoi aku ka paʻakikī o ka pilina ma waena o ka solubility a me ka mahana: i loko o kahi pae wela, e hoʻoheheʻe ʻia ka HPMC mai ka hopena, i hōʻike ʻia me ka piʻi ʻana o ka viscosity solution a i ʻole ka hoʻokumu ʻana o ka gel. Hiki mai kēia ʻano ke hoʻokokoke a ʻoi aku paha i ka wela hoʻoheheʻe o HPMC.
3. Ka hopena o ka wela ma ka hana rheological o ka solution HPMC
Hōʻike maʻamau ka ʻano rheological o ka solution HPMC i kahi hopena shear-thinning, ʻo ia hoʻi, e emi ana ka viscosity ke piʻi ka nui o ka shear rate. He hopena koʻikoʻi ka hoʻololi ʻana i ka mahana i kēia hopena shear-thinning. ʻO ka maʻamau, i ka piʻi ʻana o ka mahana, e emi ana ka viscosity o ka solution HPMC, a ʻike ʻia kona hopena shear-thinning. ʻO ia hoʻi, ma nā wela kiʻekiʻe, ʻoi aku ka hilinaʻi o ka hopena o ka HPMC ma luna o ka nui o ka shear rate, ʻo ia hoʻi, ma ke ʻano shear rate hoʻokahi, ʻoi aku ka maʻalahi o ka hopena HPMC ma ka wela wela ma mua o ka wela haʻahaʻa.
Eia kekahi, pili ka piʻi ʻana o ka mahana i ka thixotropy o ka hopena HPMC. ʻO ka Thixotropy ka waiwai i emi iho ka viscosity o kahi hoʻonā ma lalo o ka hana a ka ikaika shear, a e hoʻi mālie ka viscosity ma hope o ka hemo ʻana o ka ikaika shear. ʻO ka mea maʻamau, ʻo ka piʻi ʻana o ka wela ke alakaʻi i ka piʻi ʻana o ka thixotropy o ka solution HPMC, ʻo ia hoʻi, ma hope o ka hemo ʻana o ka ikaika shear, ʻoi aku ka mālie o ka viscosity ma mua o nā kūlana haʻahaʻa haʻahaʻa.
4. Ka hopena o ka wela ma ka hana gelation o HPMC
Loaʻa i ka HPMC kahi waiwai hoʻoheheʻe wela kū hoʻokahi, ʻo ia hoʻi, ma hope o ka hoʻomehana ʻana i kahi mahana (gel wela), e hoʻololi ka hopena HPMC mai kahi kūlana hoʻonā i kahi kūlana gel. Hoʻopilikia nui ʻia kēia kaʻina e ka mahana. Ke piʻi aʻe ka mahana, piʻi ka pilina ma waena o ka hydroxypropyl a me ka methyl substituents i loko o nā molekala HPMC, e hopena i ka hoʻopili ʻana o nā kaulahao mole, a laila e hana ai i kahi gel. He mea koʻikoʻi kēia hanana i ka ʻoihana lāʻau lapaʻau a me ka meaʻai no ka mea hiki ke hoʻohana ʻia e hoʻoponopono i ke ʻano a me ka hoʻokuʻu ʻana i nā waiwai o ka huahana.
5. Ka hoʻohana a me ke koʻikoʻi kūpono
ʻO ka hopena o ka mahana ma nā waiwai rheological o HPMC he mea koʻikoʻi nui ia i nā noi hana. No ka hoʻohana ʻana i nā hoʻonā HPMC, e like me ka hoʻomākaukau hoʻokuʻu ʻana i ka lāʻau, nā meaʻai mānoanoa, a i ʻole nā mea hoʻoponopono no nā mea kūkulu hale, pono e noʻonoʻo ʻia ka hopena o ka mahana ma nā waiwai rheological e hōʻoia i ka paʻa a me ka hana o ka huahana ma lalo o nā kūlana wela like ʻole. No ka laʻana, i ka wā e hoʻomākaukau ai i nā lāʻau lapaʻau wela, pono e noʻonoʻo ʻia ka hopena o ka hoʻololi ʻana o ka mahana i ka viscosity a me ka ʻano gelation o ka matrix HPMC no ka hoʻonui ʻana i ka helu hoʻokuʻu lāʻau.
He hopena koʻikoʻi ka mahana i nā waiwai rheological o hydroxypropyl methylcellulose. ʻO ka hoʻonui ʻia ʻana o ka mahana e hoʻemi i ka viscosity o nā hāʻina HPMC, hoʻonui i kona hopena shear-thinning a me thixotropy, a hiki ke hoʻoulu i ka gelation thermal. Ma nā noi kūpono, ʻo ka hoʻomaopopo ʻana a me ka kāohi ʻana i ka hopena o ka wela ma nā waiwai rheological o HPMC ke kī i ka hoʻonui ʻana i ka hana huahana a me nā ʻāpana kaʻina.
Ka manawa hoʻouna: Sep-05-2024