Wani nau'in polymer ne HPMC?

HPMC, ko hydroxypropyl methylcellulose, wani nau'in polymer ne na tushen cellulose wanda ake amfani dashi sosai a cikin masana'antar magunguna, abinci, da masana'antar kulawa ta sirri. Cellulose wani nau'in polymer ne na halitta wanda ke samuwa a cikin tsire-tsire kuma shine mafi yawan kwayoyin halitta a duniya. Polymer na layi ne wanda aka yi da monomers na glucose wanda ke da alaƙa ta β(1→4) glycosidic bonds.

Ana samar da HPMC ta hanyar sinadari mai canza cellulose tare da ko dai methyl ko ƙungiyoyin hydroxypropyl. Ana iya yin waɗannan gyare-gyare ta hanyar amsawar cellulose tare da reagents masu dacewa a gaban mai kara kuzari. Halin da ke tsakanin cellulose da methyl chloride ko methyl bromide yana haifar da methylcellulose, yayin da martani tsakanin cellulose da propylene oxide yana haifar da hydroxypropyl cellulose. Ana samar da HPMC ta hanyar haɗa waɗannan halayen guda biyu don gabatar da ƙungiyoyin methyl da hydroxypropyl a kan kashin bayan cellulose.

Sakamakon polymer yana da tsari mai rikitarwa wanda zai iya bambanta dangane da matakin maye gurbin (DS) na ƙungiyoyin methyl da hydroxypropyl. DS yana nufin matsakaicin adadin ƙungiyoyin hydroxyl da aka maye gurbinsu da rukunin anhydroglucose a cikin kashin bayan cellulose. Yawanci, HPMC yana da DS na 1.2 zuwa 2.5 don ƙungiyoyin methyl da 0.1 zuwa 0.3 don ƙungiyoyin hydroxypropyl. Tsarin HPMC yana da rikitarwa ta gaskiyar cewa ana iya rarraba ƙungiyoyin methyl da hydroxypropyl tare da kashin bayan cellulose, wanda ya haifar da wani nau'in polymer mai ban sha'awa tare da kewayon kaddarorin.

HPMC polymer ce mai narkewa da ruwa wanda ke samar da abu mai kama da gel lokacin da aka shayar da shi. Abubuwan gelation na HPMC sun dogara da abubuwa da yawa, ciki har da DS, nauyin kwayoyin halitta, da tattarawar polymer. Gabaɗaya, HPMC yana samar da mafi kwanciyar hankali gel a mafi girman ƙima kuma tare da ƙimar DS mafi girma. Bugu da ƙari, abubuwan gelation na HPMC na iya rinjayar pH, ƙarfin ionic, da zafin jiki na maganin.

Keɓaɓɓen kaddarorin na HPMC sun sa ya zama sinadari mai mahimmanci a aikace-aikace da yawa. A cikin masana'antar harhada magunguna, ana amfani da HPMC azaman mai ɗaure, tarwatsewa, da wakili mai ƙirƙirar fim a cikin allunan da capsules. Hakanan za'a iya amfani dashi don gyara adadin sakin kwayoyi daga nau'in sashi. A cikin masana'antar abinci, ana amfani da HPMC azaman mai kauri, stabilizer, da emulsifier. Ana amfani da shi sau da yawa a cikin abinci mai ƙarancin kitse ko rage-kalori don kwaikwayi nau'in rubutu da jin daɗin abinci mai girma. A cikin masana'antar kulawa ta sirri, ana amfani da HPMC azaman mai kauri, wakili mai ƙirƙirar fim, da emulsifier a cikin shamfu, ruwan shafawa, da sauran samfuran.

A ƙarshe, HPMC shine polymer na tushen cellulose wanda aka samar ta hanyar gyara cellulose ta hanyar sinadarai tare da ƙungiyoyin methyl da hydroxypropyl. Sakamakon polymer shine mai narkewar ruwa kuma yana da tsari mai rikitarwa wanda zai iya bambanta dangane da matakin maye gurbin da rarraba ƙungiyoyin methyl da hydroxypropyl. HPMC wani nau'in polymer ne wanda ke da aikace-aikace da yawa a cikin masana'antar harhada magunguna, abinci, da masana'antar kulawa ta sirri.