Menene danko na HPMC?

HPMC, ko Hydroxypropyl Methylcellulose, polymer roba ce da ake amfani da ita sosai a cikin magunguna, abinci, kayan kwalliya da filayen gini. Yana da kyawawan kaddarorin da yawa irin su solubility, kwanciyar hankali, nuna gaskiya da abubuwan ƙirƙirar fim azaman mai kauri, m, tsohon fim, wakili mai dakatarwa da colloid mai kariya.

Game da dankowar HPMC, ra'ayi ne mai rikitarwa saboda danko yana shafar abubuwa da yawa, kamar maida hankali, nauyin kwayoyin halitta, sauran ƙarfi, zazzabi da ƙimar ƙarfi.

Dangantaka tsakanin nauyin kwayoyin halitta da danko: Nauyin kwayoyin halitta na HPMC yana daya daga cikin muhimman abubuwan da ke ƙayyade danko. Gabaɗaya magana, mafi girman nauyin kwayoyin halitta, mafi girman ɗankowar HPMC. Saboda haka, masana'antun yawanci suna ba da samfuran HPMC tare da ma'aunin kwayoyin daban-daban don saduwa da bukatun masana'antu daban-daban. Yawan nauyin kwayoyin halitta ana bayyana shi azaman ƙimar K (kamar K100, K200, da sauransu). Girman ƙimar K, mafi girman danko.

Tasirin maida hankali: Dankowar maganin HPMC a cikin ruwa yana ƙaruwa tare da haɓaka haɓaka. Misali, 1% maida hankali na maganin HPMC na iya samun danko sau da yawa sama da na 0.5% maida hankali. Wannan yana ba da damar danko na maganin da za a sarrafa shi ta hanyar daidaita ƙaddamarwar HPMC a cikin aikace-aikacen.

Tasirin kaushi: Ana iya narkar da HPMC a cikin ruwa ko kaushi, amma daban-daban kaushi yana shafar danko. Gabaɗaya, HPMC yana da solubility mai kyau a cikin ruwa kuma yanayin danko yana da girma, yayin da danko a cikin kaushi na halitta ya bambanta dangane da polarity na sauran ƙarfi da matakin maye gurbin HPMC.

Tasirin zafin jiki: Dankowar maganin HPMC yana canzawa tare da zafin jiki. Gabaɗaya, dankowar maganin HPMC yana raguwa lokacin da zafin jiki ya ƙaru. Wannan shi ne saboda karuwar zafin jiki yana haifar da saurin motsin kwayoyin halitta da kuma ƙara yawan ruwa na maganin, wanda ya rage danko.

Tasirin ƙimar juzu'i: Maganin HPMC ruwa ne wanda ba na Newtonian ba, kuma ɗanƙoƙin sa yana canzawa tare da ƙimar ƙarfi. Wannan yana nufin cewa yayin motsawa ko yin famfo, danko yana canzawa tare da ƙarfin aiki. Gabaɗaya, maganin HPMC yana nuna halayen ɓacin rai, wato, danko yana raguwa a babban ƙimar ƙarfi.

Maki na HPMC da ƙayyadaddun bayanai: Maki daban-daban na samfuran HPMC suma suna da bambance-bambance masu mahimmanci a cikin danko. Misali, samfurin HPMC mara ƙarancin danko na iya samun danko na 20-100mPas a maida hankali na 2%, yayin da babban ƙimar samfurin HPMC na iya samun ɗankowar har zuwa 10,000-200,000 mPas a daidai wannan taro. Don haka, lokacin zabar HPMC, yana da mahimmanci a zaɓi madaidaicin ƙimar ɗanko bisa ƙayyadaddun buƙatun aikace-aikacen.

Hanyoyin gwaji na yau da kullun: Ana auna dankowar HPMC ta hanyar viscometer ko rheometer. Hanyoyin gwaji na gama gari sun haɗa da viscometer jujjuyawa da viscometer capillary. Yanayin gwaji kamar zafin jiki, maida hankali, nau'in ƙarfi, da sauransu na iya yin tasiri mai mahimmanci akan sakamakon, don haka waɗannan sigogi suna buƙatar kulawa sosai yayin gwaji.

A danko na HPMC wani hadadden siga shafi mahara dalilai, da kuma daidaitawa sa ya yadu amfani a daban-daban aikace-aikace. Ko a cikin abinci, magunguna, kayan gini ko masana'antar kayan kwalliya, fahimta da sarrafa danko na HPMC shine ɗayan mahimman abubuwan don tabbatar da ingancin samfur da aiki.