Menene aikace-aikacen CMC a cikin ƙirar magunguna?
Carboxymethylcellulose (CMC) wani abu ne da ake amfani da shi sosai a cikin kera magunguna. Yana da polysaccharide mai narkewa da ruwa wanda aka samo daga cellulose, wanda ya ƙunshi raka'o'in glucose wanda aka haɗa tare da haɗin gwiwar glycosidic. CMC ba ion ba ne, mara ɗanɗano, mara wari, da farin foda wanda ba zai iya narkewa a cikin mafi yawan kaushi na halitta. Ana amfani da shi a cikin ƙirar magunguna don haɓaka kwanciyar hankali, haɓakar rayuwa, da amincin magunguna.
Ana amfani da CMC a cikin nau'ikan magunguna iri-iri, gami da allunan, capsules, suspensions, emulsions, da man shafawa. Ana amfani da shi azaman mai ɗaure, tarwatsawa, wakili mai dakatarwa, wakili na emulsifying, mai mai, da stabilizer. Har ila yau, ana amfani da shi don ƙara danko na formulations da kuma inganta kwarara Properties na powders.
Ana amfani da CMC a cikin allunan da capsules don inganta abubuwan da ke gudana na foda, don ƙara haɓakar foda, da kuma inganta rarrabuwa da rushe kwamfutar hannu ko capsule. Hakanan ana amfani dashi azaman ɗaure don riƙe kwamfutar hannu ko capsule tare. Ana amfani da CMC a cikin dakatarwa don inganta kwanciyar hankali na dakatarwa da kuma ƙara danko na dakatarwa. Hakanan ana amfani dashi azaman wakili na emulsifying don inganta kwanciyar hankali na emulsions.
Ana amfani da CMC a cikin maganin shafawa don inganta kwanciyar hankali na maganin shafawa da kuma ƙara danko na maganin shafawa. Hakanan ana amfani dashi azaman mai mai don rage juzu'i tsakanin man shafawa da fata.
CMC gabaɗaya yana da aminci kuma ba mai guba ba. Cibiyar Abinci da Magunguna ta Amurka (FDA) ta amince da ita a matsayin mai aminci (GRAS). Hakanan Hukumar Kula da Magunguna ta Turai (EMA) ta amince da ita don amfani da samfuran magunguna.
CMC muhimmin abu ne mai haɓakawa a cikin ƙirar magunguna. Ana amfani da shi don haɓaka kwanciyar hankali, haɓakar rayuwa, da amincin magunguna. Gabaɗaya yana da aminci kuma ba mai guba ba kuma FDA da EMA sun amince da shi don amfani a cikin ƙirar magunguna.
Lokacin aikawa: Fabrairu-11-2023