Tsayawa-saki da shirye-shiryen sakin sarrafawa: Cellulose ethers kamar HPMC (hydroxypropyl methylcellulose) ana amfani da su azaman kwarangwal na hydrogel a cikin shirye-shiryen sakewa mai dorewa. Yana iya sarrafa adadin sakin kwayoyi a cikin jikin mutum don cimma tasirin warkewa. Ana iya amfani da ƙarancin dankowa HPMC azaman manne, mai kauri da kuma dakatarwa, yayin da ake amfani da babban danko mai girma HPMC ana amfani da shi don shirya allunan skeleton ci gaba-saki, capsules mai ɗorewa, da kwarangwal na hydrophilic gel skeleton ci gaba-saki Allunan.
Wakilin mai yin fim mai sutura: HPMC yana da kyawawan kaddarorin shirya fim, kuma fim ɗin da aka yi daidai ne, bayyananne, tauri, kuma ba shi da sauƙi a bi. Zai iya inganta kwanciyar hankali na miyagun ƙwayoyi kuma ya hana discoloration. Yawan taro na kowa na HPMC shine 2% zuwa 10%.
Magungunan magunguna: Cellulose ethers suna taka muhimmiyar rawa wajen gyare-gyaren shirye-shiryen azaman abubuwan haɓaka magunguna, irin su pellet ɗin ci gaba, shirye-shiryen ci gaba da sakin kwarangwal, shirye-shiryen ci gaba mai ɗorewa, ɗorewa-sakin capsules, ci gaba-sakin-saki fina-finai na magani, sake dawo da magunguna. shirye-shiryen saki da shirye-shiryen ci gaba da fitowar ruwa.
Microcrystalline Cellulose (MCC): MCC wani nau'i ne na cellulose wanda aka yi amfani da shi sosai a cikin masana'antar harhada magunguna, musamman a cikin matsawa kai tsaye da busassun granulation matakai kamar nadi compaction don shirya matsa Allunan ko granules.
Bioadhesives: Cellulose ethers, musamman nonionic da anionic ether abubuwan da suka samo asali kamar EC (ethylcellulose), HEC (hydroxyethylcellulose), HPC (hydroxypropylcellulose), MC (methylcellulose), CMC (carboxymethylcellulose) ko HPMC (hydroxypropylcellulose). Ana iya amfani da waɗannan polymers a cikin na baka, ido, farji da transdermal bioadhesives, kadai ko a hade tare da wasu polymers.
Thickeners da Stabilizers: Ana amfani da abubuwan da suka samo asali na Cellulose don yin kauri don magance maganin miyagun ƙwayoyi da tsarin watsawa kamar emulsions da suspensions. Wadannan polymers na iya ƙara danko na maganin maganin da ba na ruwa ba kamar maganin suturar kwayoyin halitta. Ƙara danko na maganin miyagun ƙwayoyi zai iya inganta haɓakar bioavailability na shirye-shirye na Topical da mucosal.
Fillers: Cellulose da abubuwan da suka samo asali ana amfani da su azaman masu cikawa a cikin ingantaccen nau'ikan sashi kamar allunan da capsules. Sun dace da yawancin sauran abubuwan haɓakawa, marasa amfani da magunguna, kuma ba a narkar da su ta hanyar enzymes na ciki na ɗan adam.
Binders: Ana amfani da ethers na cellulose azaman masu ɗaure yayin aikin granulation don taimakawa granules su samar da kiyaye mutuncin su.
Tsire-tsire: Hakanan ana amfani da ethers na cellulose don yin capsules na shuka, madadin yanayin muhalli ga capsules na gargajiya na dabba.
Tsarin bayarwa na miyagun ƙwayoyi: Ana iya amfani da ethers na Cellulose don haɓaka tsarin isar da magunguna iri-iri, gami da tsarin sarrafawa-saki da tsarin jinkiri, da kuma tsarin takamaiman rukunin yanar gizo ko takamaiman sakin magunguna.
Aikace-aikacen ethers na cellulose a cikin masana'antar harhada magunguna yana ci gaba da haɓaka, kuma tare da haɓaka sabbin nau'ikan nau'ikan allurai da sabbin abubuwan haɓakawa, ana sa ran sikelin buƙatun kasuwar sa zai ƙara haɓaka.
Lokacin aikawa: Oktoba-31-2024