Tsaro na CMC

Sodium carboxymethyl cellulose (CMC) gabaɗaya ana ɗaukarsa azaman lafiya (GRAS) don amfani da hukumomin gudanarwa kamar Hukumar Abinci da Magunguna (FDA) a Amurka da Hukumar Kare Abinci ta Turai (EFSA) a Turai lokacin amfani da ita daidai da mai kyau. Ayyukan masana'antu (GMP) da ƙa'idodin aminci da aka kafa. Anan ga bayyani na la'akarin aminci masu alaƙa da CMC:

1. Amincewa da Ka'idoji: An amince da CMC don amfani azaman ƙari na abinci a ƙasashe da yawa a duniya, gami da Amurka, Tarayyar Turai, Kanada, Ostiraliya, da Japan. An jera shi tare da hukumomin gudanarwa daban-daban azaman abin da aka ba da izini ga ƙari na abinci tare da takamaiman iyakokin amfani da ƙayyadaddun bayanai.
2. Nazarin Guba: An gudanar da bincike mai zurfi don tantance amincin CMC don amfanin ɗan adam. Waɗannan karatun sun haɗa da m, subchronic, da kuma na yau da kullun gwaje-gwaje masu guba, da kuma mutagenicity, genotoxicity, da kimar carcinogenicity. Dangane da bayanan da ake samu, ana ɗaukar CMC lafiya don amfanin ɗan adam a matakan da aka yarda.
3. Karɓar Abincin yau da kullun (ADI): Hukumomin gudanarwa sun kafa ƙimar ƙimar yau da kullun (ADI) don CMC dangane da nazarin toxicological da ƙimar aminci. ADI tana wakiltar adadin CMC wanda za'a iya cinyewa yau da kullun a tsawon rayuwa ba tare da haɗari ga lafiya ba. Ƙimar ADI ta bambanta tsakanin hukumomin gudanarwa kuma an bayyana su cikin sharuddan milligrams kowace kilogram na nauyin jiki kowace rana (mg/kg bw/day).
4. Allergenicity: CMC an samo shi ne daga cellulose, polysaccharide da ke faruwa a dabi'a da aka samu a cikin ganuwar tantanin halitta. Ba a san ya haifar da rashin lafiyan halayen a cikin yawan jama'a ba. Koyaya, mutanen da ke da masaniyar alerji ko hankali ga abubuwan da suka samo asali na cellulose yakamata suyi taka tsantsan da tuntubar kwararrun kiwon lafiya kafin cinye samfuran da ke ɗauke da CMC.
5. Tsaron narkewar abinci: CMC ba ya shiga tsarin tsarin narkewar ɗan adam kuma yana wucewa ta gastrointestinal tract ba tare da an daidaita shi ba. An yi la'akari da shi ba mai guba ba kuma ba shi da fushi ga mucosa mai narkewa. Koyaya, yawan amfani da CMC ko wasu abubuwan da ake samu na cellulose na iya haifar da rashin jin daɗi na ciki, kumburin ciki, ko gudawa a wasu mutane.
6. Yin hulɗa tare da Magunguna: Ba a san CMC don yin hulɗa tare da magunguna ba ko kuma rinjayar shayar da su a cikin gastrointestinal tract. Ana la'akari da shi dacewa da mafi yawan magungunan magunguna kuma ana amfani da shi azaman ƙari a cikin nau'ikan nau'ikan sashi na baka kamar allunan, capsules, da dakatarwa.
7. Tsaron Muhalli: CMC abu ne mai lalacewa kuma yana da alaƙa da muhalli, saboda an samo shi daga tushen sabuntawa kamar ɓangaren itace ko cellulose na auduga. Yana rushewa ta dabi'a a cikin muhalli ta hanyar aikin ƙwayoyin cuta kuma baya tarawa a cikin ƙasa ko tsarin ruwa.

A taƙaice, ana ɗaukar sodium carboxymethyl cellulose (CMC) mai lafiya don amfani idan aka yi amfani da shi daidai da ƙa'idodin tsari da ƙa'idodin aminci. An yi nazari sosai game da gubarsa, rashin lafiyar sa, lafiyar narkewar abinci, da tasirin muhalli, kuma an amince da shi don amfani da shi azaman ƙari na abinci da kayan haɓaka magunguna a ƙasashe da yawa a duniya. Kamar yadda yake tare da kowane kayan abinci ko ƙari, daidaikun mutane yakamata su cinye samfuran da ke ɗauke da CMC a matsakaici a matsayin wani ɓangare na daidaitaccen abinci kuma tuntuɓi ƙwararrun kiwon lafiya idan suna da takamaiman ƙuntatawa na abinci ko damuwa na likita.