Ana amfani da HPMC a cikin allunan shafi

Allunan shafi An kullum amfani a cikin m tsari shiri, bisa gaAllunan shafi za a iya raba kayan zuwa fodaAllunan shafi, pelletAllunan shafi, barbashiAllunan shafi, kwamfutar hannuAllunan shafi, capsuleAllunan shafi; Bisa lafazinAllunan shafi an raba kayan zuwa sukariAllunan shafi, rabin fimAllunan shafi, fimAllunan shafi (dangane da nau'ikan kayan polymer iri-iri, gami da entericAllunan shafi), kayan aiki na musammanAllunan shafi (irin su stearic acid, paraffin, polysaccharide); Bisa lafazinAllunan shafi fasaha, ana iya raba shi zuwa feshiAllunan shafi, tsomaAllunan shafi, bushewar matsa lambaAllunan shafi, electrostaticAllunan shafi da laminatingAllunan shafi. Daga cikin su, fesaAllunan shafi ita ce aka fi amfani da ita. Ka'idarsa ita ce fesaAllunan shafi ruwa a cikin ɗigon hazo da ke rufe saman kayan (foda, barbashi, allunan). Kuma da sauri ya bushe don samar daAllunan shafi Layer: bisa gaAllunan shafi An raba manufar zuwa ruwa mai narkewaAllunan shafi, ciki mai narkewaAllunan shafi, maras narkewaAllunan shafi, Saki a hankaliAllunan shafi, cikiAllunan shafi.

MatsayinAllunan shafi ya haɗa da: (1) hana danshi, haske, warewar iska don ƙara kwanciyar hankali na miyagun ƙwayoyi; (2) Rufe wari mara kyau, rage kuzari; (3) Inganta bayyanar, sauƙin ganewa; (4) Sarrafa wurin sakin miyagun ƙwayoyi, kamar a cikin ruwan 'ya'yan itace mai sauƙi don lalacewa ta yadda za'a saki a cikin hanji: (5) sarrafa watsawar ƙwayoyi, saurin sakin: (6) shawo kan rashin daidaituwa, da dai sauransu.Allunan shafi abu ya kamata ya sami waɗannan buƙatun: mara guba, babu inertia sinadarai, barga cikin zafi, haske, ruwa, iska, kuma baya amsawa tare daAllunan shafi kwayoyi; (2) za a iya narkar da cikin ko'ina tarwatsa a cikin watsawa matsakaici dace daAllunan shafi: (3) na iya samar da ci gaba, m, m Layer, tsattsauran juriya kuma yana da kyakkyawan keɓewar ruwa, keɓancewar danshi, shading, haɓakar iska;④Solubility ya kamata ya dace da buƙatun - ƙayyadaddun, wani lokacin ba buƙatar PH ya shafa ba, wani lokacin kawai zai iya narke a cikin kewayon PH na musamman. Wani nau'in kayan da ke da halayen sama a lokaci guda ba a gani da yawa, dalili yana so ya yi amfani da gaurayeAllunan shafi abu mafi, domin koyi da juna.

TabletAllunan shafi ita ce aka fi amfani da ita, tana yawan amfani da tukunyaAllunan shafi da bututu da aka binneAllunan shafi (high inganciAllunan shafi injiAllunan shafi), na ƙarshe ya fi kyau ga fimAllunan shafi. Gado mai ruwaAllunan shafi ya fi dacewa da kayan da ƙananan ƙwayar ƙwayar ƙwayar cuta kamar pellets da foda. Idan aka kwatanta da sukariAllunan shafi, fimAllunan shafi yana da fa'idodi da yawa 1) Gajarta lokaci kuma rage farashin kayan; (2) babu wani gagarumin karuwa a nauyi: (3) babu bukatar kasa Layer: (4) karfi, murkushe da fatattaka juriya: (5) za a iya buga, kuma ba ya shafar guntu haruffa;6) Zai iya kare samfurin yadda ya kamata daga tasirin haske, iska da ruwa; (7) Babu wani mummunan tasiri akan lokacin rushewa 8) kayan ado 9) yana ba da damar amfani da ruwan da ba ruwa baAllunan shafi; Ana iya daidaita matakai da kayan aiki. Yanzu ci gaban sabon samfurinAllunan shafi shiri gabaɗaya ya ɗauki fimAllunan shafi, fimAllunan shafi rubutun asali na asali ya haɗa da wakilin shirya fim (Allunan shafi abu), sauran ƙarfi, plasticizer, colorant, kuma iya ƙara pore-halawa wakili, insoluble filler, da dai sauransu .. A abun da ke ciki na fimAllunan shafi takardar sayan magani shine mabuɗin samun nasararAllunan shafi. A halin yanzu, fim mai narkewa da ruwaAllunan shafi Abubuwan da aka saba amfani da su sun haɗa da hydroxypropyl methyl cellulose (HPMC) da hydroxypropyl cellulose (HPC). Polyethylene glycol (PEG), polyethylene pyrrolidone (PVP), kayan aiki masu narkewa ciki har da resin-mai narkewa acrylic guduro, hydroxypropyl methyl cellulose phthalate (HPMCP). Cellulose acetate phthalate ester (CAP). Shellac, kayan da ba a iya narkewa sun haɗa da ethyl cellulose (EC), zein.

A tsawon shekaru, fimAllunan shafi ya samu ci gaba mai ban mamaki. Ma'aunin gargajiyaAllunan shafi tsarin amfaniHPMC(hydroxypropyl methylcellulose) a matsayin babban polymer, wanda har yanzu ana amfani dashi a yau. HPMC- tushenAllunan shafi Tsarin yana ba da isasshen aiki, amma har yanzu akwai sauran damar ingantawa. HPMCAllunan shafi Fim bazai manne da kwamfutar hannu da kyau ba, yawanci tsayiAllunan shafi lokaci, yana haifar da jinkirin samarwa. Gabatarwa na gabaPVA tushen Allunan shafi tsarin ya kara inganta ayyuka, yana haifar da mafi kyauAllunan shafi aiki da saurin samarwa da sauri, wanda ke nufin cewa lahani ba shi da yuwuwar faruwa a cikin allunan.

Yayin da dankowar HPMC ke ƙaruwa, ƙarfin fim ɗin da HPMC ya kirkira yana ƙaruwa daidai, kuma a ƙarshe ya kai matsakaicin ƙarfin fim ɗin baya ƙaruwa tare da haɓakar danko na HPMC.

A cikinAllunan shafi, don cimma mafi inganciAllunan shafi, sau da yawa inganta daAllunan shafi ruwa m abun ciki, wanda zai kai gaAllunan shafi ruwa danko ne ma high, zabi low danko HPMC iya yadda ya kamata warware wannan matsala, amma kai ga fim ƙarfi ya shafi. Don daidaita waɗannan matsalolin tagwaye, hada polymers ya zama kayan aiki na kowa.

Kamar yaddaHPMCE15 abun ciki a hankali yana ƙaruwa, danko na cakudaHPMCE5 daHPMCE15 kuma a hankali yana ƙaruwa.

A cikin sukariAllunan shafi, mun kuma tashi daga fasaha zuwa kimiyya. Kayayyakin da aka lulluɓe da sukari suna da daɗi sosai saboda suna da santsi, mai sheki, gamawa mai daɗi wanda ke rufe ɗanɗano da ɗaci. Amma babban kalubale a cikin sukariAllunan shafi kwanta a cikin yawan aiki da kuma reproducibility. SugarAllunan shafi tsari ne mai wahala sosai kuma mai ɗaukar lokaci kuma yana iya bambanta daga tsari zuwa tsari dangane da mutumin da ke yin aikin.Allunan shafi.