Hydroxyethyl Cellulose (HEC) da sauran cellulose ethers (irin su hydroxypropyl methylcellulose (HPMC), methylcellulose (MC), hydroxypropyl cellulose (HPC) da kuma carboxymethyl cellulose (CMC)) ne multifunctional polymers amfani da ko'ina a masana'antu, yi, magani, abinci da kullum. masana'antun sinadarai. Wadannan abubuwan da suka samo asali na cellulose an yi su ne ta hanyar gyaran gyare-gyaren sinadarai kuma suna da kyakkyawar solubility na ruwa, kauri, kwanciyar hankali da kayan aikin fim.
1. Hydroxyethyl cellulose (HEC)
1.1 Tsarin Sinadarai da Kayafai
Hydroxyethyl Cellulose (HEC) an yi shi ta hanyar hydroxyethylation na cellulose tare da ethylene oxide a ƙarƙashin yanayin alkaline. Tsarin asali na HEC shine haɗin ether da aka kafa ta hanyar maye gurbin ƙungiyar hydroxyl a cikin kwayar halitta ta cellulose ta ƙungiyar hydroxyethyl. Wannan tsarin yana ba da kaddarorin HEC na musamman:
Ruwa mai narkewa: HEC yana narkewa a cikin ruwan sanyi da ruwan zafi don samar da ingantaccen maganin colloidal.
Thickening: HEC yana da kyawawan kaddarorin kauri kuma ana amfani dashi ko'ina cikin aikace-aikacen da ke buƙatar sarrafa danko.
Kwanciyar hankali: Maganin HEC yana da babban kwanciyar hankali a cikin jeri na pH daban-daban.
Biocompatibility: HEC ba mai guba ba ne, mara fushi, da abokantaka ga jikin mutum da muhalli.
1.2 Filayen aikace-aikace
Kayan gini: ana amfani da shi azaman mai kauri da mai riƙe ruwa don turmi siminti da samfuran gypsum.
Rubutu da fenti: ana amfani da su azaman mai kauri, wakili mai dakatarwa da stabilizer.
Sinadaran yau da kullun: ana amfani da su azaman mai kauri a cikin buƙatun yau da kullun kamar wanki da shamfu.
Filin magunguna: ana amfani da shi azaman manne, mai kauri da wakili mai dakatarwa don allunan magunguna.
1.3 Fa'idodi da rashin amfani
Abũbuwan amfãni: mai kyau ruwa solubility, sinadaran kwanciyar hankali, m pH adaptability da rashin guba.
Rashin hasara: rashin ƙarfi mara ƙarfi a cikin wasu kaushi, kuma farashin na iya zama dan kadan sama da wasu ethers cellulose.
2. Kwatanta sauran ethers cellulose
2.1 Hydroxypropyl methylcellulose (HPMC)
2.1.1 Tsarin sinadaran da kaddarorin
Ana yin HPMC daga cellulose ta hanyar methylation da halayen hydroxypropylation. Tsarinsa ya ƙunshi duka methoxy (-OCH3) da hydroxypropoxy (-OCH2CH (OH) CH3).
Ruwa mai narkewa: HPMC ya narke a cikin ruwan sanyi don samar da maganin colloidal na gaskiya; yana da ƙarancin narkewa a cikin ruwan zafi.
Kauri dukiya: Yana da kyau kwarai thickening ikon.
Gelling Properties: Yana samar da gel lokacin da aka yi zafi kuma ya dawo zuwa asalinsa lokacin da aka sanyaya.
2.1.2 Yankunan aikace-aikace
Kayan gini: Ana amfani da shi azaman mai kauri da mai riƙe ruwa don tushen siminti da kayan gypsum.
Abinci: Ana amfani dashi azaman emulsifier da stabilizer.
Magani: Ana amfani da shi azaman kayan haɓaka magunguna don capsules da allunan.
2.1.3 Fa'idodi da rashin amfani
Abũbuwan amfãni: Good thickening yi da gelling Properties.
Hasara: Yana kula da zafin jiki kuma yana iya gazawa a aikace-aikacen zafin jiki mai girma.
2.2 Methyl cellulose (MC)
2.2.1 Tsarin sinadaran da kaddarorin
Ana samun MC ta hanyar methylation na cellulose kuma galibi ya ƙunshi abubuwan maye gurbin methoxy (-OCH3).
Solubility na ruwa: narke da kyau a cikin ruwan sanyi don samar da maganin colloidal na gaskiya.
Kauri: yana da tasiri mai mahimmanci.
Thermal Gelation: Yana samar da gel lokacin da mai zafi da raguwa lokacin sanyaya.
2.2.2 Yankunan aikace-aikace
Kayan gini: ana amfani da shi azaman mai kauri da mai riƙe ruwa don turmi da fenti.
Abinci: ana amfani dashi azaman emulsifier da stabilizer.
2.2.3 Fa'idodi da rashin amfani
Abũbuwan amfãni: ƙarfi mai ƙarfi mai ƙarfi, galibi ana amfani dashi a fasahar sarrafa sanyi.
Rashin hasara: zafi-m, ba za a iya amfani da a high yanayin zafi.
2.3 Hydroxypropyl cellulose (HPC)
2.3.1 Tsarin sinadaran da kaddarorin
Ana samun HPC ta hanyar hydroxypropyl cellulose. Tsarinsa ya ƙunshi hydroxypropoxy (-OCH2CH(OH)CH3).
Ruwa mai narkewa: narke cikin ruwan sanyi da kaushi na halitta.
Thicking: mai kyau thickening yi.
Abubuwan da ke ƙirƙirar fim: suna samar da fim mai ƙarfi.
2.3.2 Filayen aikace-aikacen
Magani: ana amfani dashi azaman kayan shafa da kayan aikin kwamfutar hannu don magunguna.
Abinci: ana amfani dashi azaman thickener da stabilizer.
2.3.3 Fa'idodi da rashin amfani
Abũbuwan amfãni: Multi-warkar da solubility da kyau kwarai film-kafa dukiya.
Rashin hasara: babban farashi.
2.4 Carboxymethyl cellulose (CMC)
2.4.1 Tsarin sinadaran da halaye
Ana yin CMC ta hanyar mayar da martani ga cellulose tare da acid chloroacetic, kuma ya ƙunshi ƙungiyar carboxymethyl (-CH2COOH) a cikin tsarinta.
Ruwa mai narkewa: mai narkewa a cikin ruwan sanyi da ruwan zafi.
Thickening dukiya: gagarumin thickening sakamako.
Ionicity: nasa ne na anionic cellulose ether.
2.4.2 Filayen aikace-aikacen
Abinci: ana amfani dashi azaman thickener da stabilizer.
Sinadaran yau da kullun: ana amfani da su azaman mai kauri don wanka.
Yin takarda: ana amfani dashi azaman ƙari don shafa takarda.
2.4.3 Fa'idodi da rashin amfani
Abũbuwan amfãni: mai kyau thickening da fadi da aikace-aikace filayen.
Rashin hasara: masu kula da electrolytes, ions a cikin bayani na iya rinjayar aiki.
3. Cikakken kwatance
3.1 Yin kauri
HEC da HPMC suna da irin wannan aikin yin kauri kuma duka biyun suna da tasirin kauri mai kyau. Duk da haka, HEC yana da mafi kyawun solubility na ruwa kuma ya dace da aikace-aikacen da ke buƙatar bayyana gaskiya da ƙananan fushi. HPMC ya fi amfani a aikace-aikacen da ke buƙatar dumama zuwa gel saboda abubuwan thermogel ɗin sa.
3.2 Ruwa mai narkewa
Ana iya narkar da HEC da CMC a cikin ruwan sanyi da ruwan zafi, yayin da HPMC da MC galibi ana narkar da su cikin ruwan sanyi. An fi son HPC lokacin da ake buƙatar daidaitawar abubuwa da yawa.
3.3 Farashin da kewayon aikace-aikace
HEC yawanci ana farashi matsakaici kuma ana amfani dashi ko'ina. Kodayake HPC yana da kyakkyawan aiki, yawanci ana amfani dashi a aikace-aikacen buƙatu masu girma saboda tsadar sa. CMC yana da wuri a yawancin aikace-aikace masu rahusa tare da ƙarancin farashi da kyakkyawan aiki.
Hydroxyethyl cellulose (HEC) ya zama daya daga cikin mafi yadu amfani cellulose ethers saboda da kyau ruwa solubility, kwanciyar hankali da thickening ikon. Idan aka kwatanta da sauran ethers cellulose, HEC yana da wasu abũbuwan amfãni a cikin ruwa solubility da kuma sinadaran kwanciyar hankali, kuma ya dace da aikace-aikace da bukatar m mafita da kuma m pH adaptability. HPMC ta yi fice a wasu takamaiman wurare saboda kauri da kaddarorin gelling na thermal, yayin da HPC da CMC ke da matsayi mai mahimmanci a cikin fagagen aikace-aikacen su saboda kaddarorin su na fim da fa'idodin tsada. Dangane da takamaiman buƙatun aikace-aikacen, zabar ether ɗin cellulose daidai zai iya haɓaka aikin samfur da ƙimar farashi.
Lokacin aikawa: Yuli-10-2024